Organ-on-a-chip model of vascularized human bone marrow niches

Bone marrow niches (endosteal and perivascular) play important roles in both normal bone marrow function and pathological processes such as cancer cell dormancy. Unraveling the mechanisms underlying these events in humans has been severely limited by models that cannot dissect dynamic events at the...

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Bibliographic Details
Published in:	Biomaterials Vol. 280; p. 121245
Main Authors:	Glaser, Drew E., Curtis, Matthew B., Sariano, Peter A., Rollins, Zachary A., Shergill, Bhupinder S., Anand, Aravind, Deely, Alyssa M., Shirure, Venktesh S., Anderson, Leif, Lowen, Jeremy M., Ng, Natalie R., Weilbaecher, Katherine, Link, Daniel C., George, Steven C.
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.01.2022
Subjects:	biocompatible materials Bone and Bones Bone Marrow Bone Marrow Cells Breast cancer Cell Differentiation - physiology dormancy doxorubicin Hematopoiesis Hematopoiesis - physiology Hematopoietic Stem Cells Humans Lab-On-A-Chip Devices neoplasm cells neutrophils Organ-on-a-chip Stem Cell Niche stem cells Tissue engineering Organ-on-a-chip Breast cancer Tissue engineering Hematopoiesis
ISSN:	0142-9612, 1878-5905, 1878-5905
Online Access:	Get full text
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