Organ-on-a-chip model of vascularized human bone marrow niches

Bone marrow niches (endosteal and perivascular) play important roles in both normal bone marrow function and pathological processes such as cancer cell dormancy. Unraveling the mechanisms underlying these events in humans has been severely limited by models that cannot dissect dynamic events at the...

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Vydáno v:	Biomaterials Ročník 280; s. 121245
Hlavní autoři:	Glaser, Drew E., Curtis, Matthew B., Sariano, Peter A., Rollins, Zachary A., Shergill, Bhupinder S., Anand, Aravind, Deely, Alyssa M., Shirure, Venktesh S., Anderson, Leif, Lowen, Jeremy M., Ng, Natalie R., Weilbaecher, Katherine, Link, Daniel C., George, Steven C.
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Netherlands Elsevier Ltd 01.01.2022
Témata:	biocompatible materials Bone and Bones Bone Marrow Bone Marrow Cells Breast cancer Cell Differentiation - physiology dormancy doxorubicin Hematopoiesis Hematopoiesis - physiology Hematopoietic Stem Cells Humans Lab-On-A-Chip Devices neoplasm cells neutrophils Organ-on-a-chip Stem Cell Niche stem cells Tissue engineering Organ-on-a-chip Breast cancer Tissue engineering Hematopoiesis
ISSN:	0142-9612, 1878-5905, 1878-5905
On-line přístup:	Získat plný text
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