Dietary dicarboxylic acids provide a nonstorable alternative fat source that protects mice against obesity

Dicarboxylic fatty acids are generated in the liver and kidney in a minor pathway called fatty acid ω-oxidation. The effects of consuming dicarboxylic fatty acids as an alternative source of dietary fat have not been explored. Here, we fed dodecanedioic acid, a 12-carbon dicarboxylic (DC12), to mice...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	The Journal of clinical investigation Ročník 134; číslo 12
Hlavní autoři:	Goetzman, Eric S., Zhang, Bob B., Zhang, Yuxun, Bharathi, Sivakama S., Bons, Joanna, Rose, Jacob, Shah, Samah, Solo, Keaton J., Schmidt, Alexandra V., Richert, Adam C., Mullett, Steven J., Gelhaus, Stacy L., Rao, Krithika S., Shiva, Sruti S., Pfister, Katherine E., Silva Barbosa, Anne, Sims-Lucas, Sunder, Dobrowolski, Steven F., Schilling, Birgit
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States American Society for Clinical Investigation 15.06.2024
Témata:	Acyl-CoA Oxidase - genetics Acyl-CoA Oxidase - metabolism Adipose Tissue - metabolism Amino acids Animals Carboxylic acids Care and treatment Dextrose Dicarboxylic Acids - administration & dosage Dicarboxylic Acids - metabolism Dicarboxylic Acids - pharmacology Dietary fat Dietary Fats - administration & dosage Dietary Fats - metabolism Dietary Fats - pharmacology Fatty acids Fatty Acids - metabolism Glucose Health aspects Liver Liver - metabolism Male Metabolism Mice Mice, Inbred C57BL Obesity Obesity - metabolism Obesity - prevention & control Oxidases Oxidation-Reduction Peroxisomes - metabolism Physiological aspects Testing Type 2 diabetes United States Pennsylvania Fatty acid oxidation Obesity Mitochondria Metabolism
ISSN:	1558-8238, 0021-9738, 1558-8238
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Buďte první, kdo okomentuje tento záznam!