Nanomaterial-based blood-brain-barrier (BBB) crossing strategies

Increasing attention has been paid to the diseases of central nervous system (CNS). The penetration efficiency of most CNS drugs into the brain parenchyma is rather limited due to the existence of blood-brain barrier (BBB). Thus, BBB crossing for drug delivery to CNS remains a significant challenge...

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Bibliographic Details
Published in:	Biomaterials Vol. 224; p. 119491
Main Authors:	Xie, Jinbing, Shen, Zheyu, Anraku, Yasutaka, Kataoka, Kazunori, Chen, Xiaoyuan
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.12.2019
Subjects:	Animals biocompatibility biodegradability blood-brain barrier Blood-brain barrier (BBB) Blood-Brain Barrier - metabolism brain Central nervous system (CNS) Central Nervous System Diseases - pathology Clinical Trials as Topic Disease Models, Animal drug carriers Drug Delivery Systems drugs Humans Nanomaterials Nanostructures - chemistry parenchyma (animal tissue) peptides toxicity Nanomaterials Drug delivery systems Central nervous system (CNS) Blood-brain barrier (BBB)
ISSN:	0142-9612, 1878-5905, 1878-5905
Online Access:	Get full text
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