Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD): Current Perspectives

Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease-mineral and bone disorder (CKD-MBD), most CKD patients are still affected by the consequences of abnormalities of CKD-MBD. This important clinical complication o...

Celý popis

Uloženo v:

Podrobná bibliografie
Vydáno v:	International journal of nephrology and renovascular disease Ročník 12; s. 263 - 276
Hlavní autoři:	Waziri, Bala, Duarte, Raquel, Naicker, Saraladevi
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	New Zealand Dove Medical Press Limited 01.12.2019 Taylor & Francis Ltd Dove Dove Medical Press
Témata:	Aluminum Biological markers Bone diseases Calcification Calcium phosphates chronic kidney disease-mineral and bone disorder Chronic kidney failure Clinical trials Drinking water emerging trends Endocrine system Fibroblast growth factor 23 Fibroblast growth factors Fibroblasts Fractures Growth factors Hemodialysis Hormones Hypotheses Kidney diseases management Metabolism Minerals Parathyroid Parathyroid hormone Parathyroid hormones Pathogenesis Phosphate binders Phosphates Review updated pathogenesis Vitamin D updated pathogenesis management emerging trends chronic kidney disease–mineral and bone disorder
ISSN:	1178-7058, 1178-7058
On-line přístup:	Získat plný text
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Abstract	Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease-mineral and bone disorder (CKD-MBD), most CKD patients are still affected by the consequences of abnormalities of CKD-MBD. This important clinical complication of CKD continues to be studied, in order to improve the understanding and management of CKD-MBD. Some notable discoveries include the role of fibroblast growth factor 23 (FGF23) in the pathogenesis of CKD-MBD, leading to a shift from the previous well-established classic trade-off hypothesis to the updated trade-off hypothesis. More recently, there has been a shift from the treatment of CKD-MBD based on a single level of biomarkers to serial measurements of calcium, phosphate and parathyroid hormone (PTH). Furthermore, some clinical trials have emerged after the 2009 Kidney Disease-Improving Global Outcomes (KDIGO) Guidelines, leading to the 2017 KDIGO updated recommendations. Hence, this review gives an overview of the rapidly evolving trends in CKD-MBD, linking the past and current concepts of CKD-MBD.
AbstractList	Bala Waziri,1,2 Raquel Duarte,1 Saraladevi Naicker1 1Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; 2Department of Medicine, Ibrahim Badamasi Babangida Specialist Hospital, Minna, NigeriaCorrespondence: Bala WaziriDepartment of Medicine, Ibrahim Badamasi Babangida Specialist Hospital, Km 10, Paiko Road, Minna, NigeriaEmail balawaziri@gmail.comAbstract: Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease-mineral and bone disorder (CKD-MBD), most CKD patients are still affected by the consequences of abnormalities of CKD-MBD. This important clinical complication of CKD continues to be studied, in order to improve the understanding and management of CKD-MBD. Some notable discoveries include the role of fibroblast growth factor 23 (FGF23) in the pathogenesis of CKD-MBD, leading to a shift from the previous well-established classic trade-off hypothesis to the updated trade-off hypothesis. More recently, there has been a shift from the treatment of CKD-MBD based on a single level of biomarkers to serial measurements of calcium, phosphate and parathyroid hormone (PTH). Furthermore, some clinical trials have emerged after the 2009 Kidney Disease-Improving Global Outcomes (KDIGO) Guidelines, leading to the 2017 KDIGO updated recommendations. Hence, this review gives an overview of the rapidly evolving trends in CKD-MBD, linking the past and current concepts of CKD-MBD.Keywords: chronic kidney disease-mineral and bone disorder, updated pathogenesis, emerging trends, management Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease-mineral and bone disorder (CKD-MBD), most CKD patients are still affected by the consequences of abnormalities of CKD-MBD. This important clinical complication of CKD continues to be studied, in order to improve the understanding and management of CKD-MBD. Some notable discoveries include the role of fibroblast growth factor 23 (FGF23) in the pathogenesis of CKD-MBD, leading to a shift from the previous well-established classic trade-off hypothesis to the updated trade-off hypothesis. More recently, there has been a shift from the treatment of CKD-MBD based on a single level of biomarkers to serial measurements of calcium, phosphate and parathyroid hormone (PTH). Furthermore, some clinical trials have emerged after the 2009 Kidney Disease-Improving Global Outcomes (KDIGO) Guidelines, leading to the 2017 KDIGO updated recommendations. Hence, this review gives an overview of the rapidly evolving trends in CKD-MBD, linking the past and current concepts of CKD-MBD.Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease-mineral and bone disorder (CKD-MBD), most CKD patients are still affected by the consequences of abnormalities of CKD-MBD. This important clinical complication of CKD continues to be studied, in order to improve the understanding and management of CKD-MBD. Some notable discoveries include the role of fibroblast growth factor 23 (FGF23) in the pathogenesis of CKD-MBD, leading to a shift from the previous well-established classic trade-off hypothesis to the updated trade-off hypothesis. More recently, there has been a shift from the treatment of CKD-MBD based on a single level of biomarkers to serial measurements of calcium, phosphate and parathyroid hormone (PTH). Furthermore, some clinical trials have emerged after the 2009 Kidney Disease-Improving Global Outcomes (KDIGO) Guidelines, leading to the 2017 KDIGO updated recommendations. Hence, this review gives an overview of the rapidly evolving trends in CKD-MBD, linking the past and current concepts of CKD-MBD. Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease--mineral and bone disorder (CKDMBD), most CKD patients are still affected by the consequences of abnormalities of CKDMBD. This important clinical complication of CKD continues to be studied, in order to improve the understanding and management of CKD-MBD. Some notable discoveries include the role of fibroblast growth factor 23 (FGF23) in the pathogenesis of CKDMBD, leading to a shift from the previous well-established classic trade-off hypothesis to the updated trade-off hypothesis. More recently, there has been a shift from the treatment of CKD-MBD based on a single level of biomarkers to serial measurements of calcium, phosphate and parathyroid hormone (PTH). Furthermore, some clinical trials have emerged after the 2009 Kidney Disease-Improving Global Outcomes (KDIGO) Guidelines, leading to the 2017 KDIGO updated recommendations. Hence, this review gives an overview of the rapidly evolving trends in CKD-MBD, linking the past and current concepts of CKD-MBD. Keywords: chronic kidney disease-mineral and bone disorder, updated pathogenesis, emerging trends, management Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease–mineral and bone disorder (CKD-MBD), most CKD patients are still affected by the consequences of abnormalities of CKD-MBD. This important clinical complication of CKD continues to be studied, in order to improve the understanding and management of CKD-MBD. Some notable discoveries include the role of fibroblast growth factor 23 (FGF23) in the pathogenesis of CKD-MBD, leading to a shift from the previous well-established classic trade-off hypothesis to the updated trade-off hypothesis. More recently, there has been a shift from the treatment of CKD-MBD based on a single level of biomarkers to serial measurements of calcium, phosphate and parathyroid hormone (PTH). Furthermore, some clinical trials have emerged after the 2009 Kidney Disease-Improving Global Outcomes (KDIGO) Guidelines, leading to the 2017 KDIGO updated recommendations. Hence, this review gives an overview of the rapidly evolving trends in CKD-MBD, linking the past and current concepts of CKD-MBD. Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease--mineral and bone disorder (CKDMBD), most CKD patients are still affected by the consequences of abnormalities of CKDMBD. This important clinical complication of CKD continues to be studied, in order to improve the understanding and management of CKD-MBD. Some notable discoveries include the role of fibroblast growth factor 23 (FGF23) in the pathogenesis of CKDMBD, leading to a shift from the previous well-established classic trade-off hypothesis to the updated trade-off hypothesis. More recently, there has been a shift from the treatment of CKD-MBD based on a single level of biomarkers to serial measurements of calcium, phosphate and parathyroid hormone (PTH). Furthermore, some clinical trials have emerged after the 2009 Kidney Disease-Improving Global Outcomes (KDIGO) Guidelines, leading to the 2017 KDIGO updated recommendations. Hence, this review gives an overview of the rapidly evolving trends in CKD-MBD, linking the past and current concepts of CKD-MBD.
Audience	Academic
Author	Waziri, Bala Naicker, Saraladevi Duarte, Raquel
Author_xml	– sequence: 1 givenname: Bala orcidid: 0000-0001-6291-6610 surname: Waziri fullname: Waziri, Bala – sequence: 2 givenname: Raquel orcidid: 0000-0003-2750-2062 surname: Duarte fullname: Duarte, Raquel – sequence: 3 givenname: Saraladevi orcidid: 0000-0002-7058-9725 surname: Naicker fullname: Naicker, Saraladevi
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/31920363$$D View this record in MEDLINE/PubMed
BookMark	eNptkk1v0zAYgC00xEbZkSuKhITGIcMfievsgLS1fJRtgAacLdd-07pK7WInk3bjP_AP-SU4awfttOSQyH7ex34_nqI95x0g9JzgY0qK4ZvJp89X4-NvpCKk5I_QASFDkQ9xKfa2_vfRYYwLnB5WcU7pE7TPSEUx4-wAXY3mwTurs3NrHNxkYxtBRfjz6_eldRBUkylnsrN0bL_lg4GQHY3Ox_nl2fj1STbqQgDXZl8hxBXo1l5DfIYe16qJcLj5DtCP9---jz7mF18-TEanF7nmRdnmUJRlCYQQhQkzeMpLUxZTxoiqSlpoqrGgyhhcM2B6WGMmaC0EJobVhvMEDtBk7TVeLeQq2KUKN9IrK28XfJhJFVqrG5AVF0VpqAGBWQFsOIWhFhUTFTYCgyqS6-3ateqmSzA65ZRy35Hu7jg7lzN_LXnFSpqsA3S0EQT_s4PYyqWNGppGOfBdlJQxTsuC8P7eL--hC98Fl0qVqCK1SdBK_KdmKiVgXe3TubqXylOe2l2IvoUDdPwAlV4DS6tT12qb1ncCXm0FzEE17Tz6pmutd3EXfLFdkX-luBudBLA1oIOPMUAttW1V70lXsI0kWPYzKm9nVG5mNEXl96LuxA_zfwELLuMW
CitedBy_id	crossref_primary_10_1055_a_1951_1398 crossref_primary_10_1080_0886022X_2024_2449572 crossref_primary_10_3390_jcm13154378 crossref_primary_10_7759_cureus_52253 crossref_primary_10_1007_s11255_021_02820_y crossref_primary_10_2215_CJN_0000000000000538 crossref_primary_10_3390_app13053212 crossref_primary_10_1016_j_bone_2022_116581 crossref_primary_10_1111_sdi_13253 crossref_primary_10_3390_app15031164 crossref_primary_10_3390_nu12113289 crossref_primary_10_1016_j_clnu_2022_04_017 crossref_primary_10_1111_hdi_13265 crossref_primary_10_3390_nu13062065 crossref_primary_10_1186_s40842_024_00183_8 crossref_primary_10_1016_j_arr_2025_102776 crossref_primary_10_3390_biomedicines12112464 crossref_primary_10_34067_KID_0000000773 crossref_primary_10_4102_ajlm_v14i1_2700 crossref_primary_10_3389_fendo_2023_1226917 crossref_primary_10_1002_ccr3_70205 crossref_primary_10_1111_hdi_13268 crossref_primary_10_1159_000541076 crossref_primary_10_25259_IJN_66_2024 crossref_primary_10_3390_diagnostics13193158 crossref_primary_10_1055_a_1655_4362 crossref_primary_10_1113_EP092401 crossref_primary_10_3390_diagnostics12092221 crossref_primary_10_3390_nu14194082 crossref_primary_10_1177_1098612X241234984 crossref_primary_10_3390_healthcare11030313 crossref_primary_10_3390_jcm12196306 crossref_primary_10_1039_D1FO03867B crossref_primary_10_3390_nu15163623 crossref_primary_10_1016_j_xkme_2025_101080 crossref_primary_10_7759_cureus_67349 crossref_primary_10_1007_s42399_025_01854_y crossref_primary_10_1016_j_bonr_2020_100298 crossref_primary_10_1080_0886022X_2021_1931318 crossref_primary_10_1111_jvim_15949 crossref_primary_10_3389_fendo_2024_1489676 crossref_primary_10_1111_hdi_13138 crossref_primary_10_3389_fmed_2023_1155426 crossref_primary_10_1007_s00774_021_01248_9 crossref_primary_10_1053_j_jrn_2024_03_011 crossref_primary_10_5114_amsad_192427 crossref_primary_10_3389_fendo_2023_1274669 crossref_primary_10_1515_cclm_2022_0635 crossref_primary_10_3390_ijms22136875 crossref_primary_10_1007_s10722_025_02528_3 crossref_primary_10_33086_ijmlst_v6i2_5864 crossref_primary_10_3889_oamjms_2023_10631 crossref_primary_10_1016_j_radcr_2024_08_142 crossref_primary_10_1016_j_jmbbm_2024_106506 crossref_primary_10_2186_jpr_JPR_D_23_00016 crossref_primary_10_1681_ASN_2020101398 crossref_primary_10_1038_s41598_021_94264_8 crossref_primary_10_1161_ATVBAHA_122_318834 crossref_primary_10_3390_biomedicines12040911 crossref_primary_10_1080_0886022X_2025_2530162 crossref_primary_10_3390_diagnostics12040880 crossref_primary_10_1002_adhm_202500550 crossref_primary_10_1007_s10157_021_02104_w crossref_primary_10_1080_15376516_2023_2195488 crossref_primary_10_1177_2399369320951579 crossref_primary_10_1186_s12872_022_02879_0 crossref_primary_10_5527_wjn_v14_i3_108406 crossref_primary_10_4330_wjc_v15_i3_76 crossref_primary_10_1038_s41598_024_55326_9 crossref_primary_10_1186_s12882_024_03771_z crossref_primary_10_5435_JAAOSGlobal_D_23_00043 crossref_primary_10_1007_s11154_021_09693_7 crossref_primary_10_1159_000539030 crossref_primary_10_1007_s00423_024_03539_x crossref_primary_10_1186_s41100_025_00634_7 crossref_primary_10_3389_fphys_2023_1083725 crossref_primary_10_1007_s00467_021_05146_0 crossref_primary_10_1016_j_cca_2021_06_004 crossref_primary_10_3390_app131910938 crossref_primary_10_1186_s12911_024_02421_6
ContentType	Journal Article
Copyright	2019 Waziri et al. COPYRIGHT 2019 Dove Medical Press Limited 2019. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2019 Waziri et al. 2019 Waziri et al.
Copyright_xml	– notice: 2019 Waziri et al. – notice: COPYRIGHT 2019 Dove Medical Press Limited – notice: 2019. This work is licensed under https://creativecommons.org/licenses/by-nc/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2019 Waziri et al. 2019 Waziri et al.
DBID	AAYXX CITATION NPM 3V. 7X7 7XB 8FE 8FH 8FI 8FJ 8FK 8G5 ABUWG AFKRA AZQEC BBNVY BENPR BHPHI CCPQU DWQXO FYUFA GHDGH GNUQQ GUQSH HCIFZ K9. LK8 M0S M2O M7P MBDVC PHGZM PHGZT PIMPY PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS Q9U 7X8 5PM DOA
DOI	10.2147/IJNRD.S191156
DatabaseName	CrossRef PubMed ProQuest Central (Corporate) Health & Medical Collection ProQuest Central (purchase pre-March 2016) ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) Research Library (Alumni) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Collection ProQuest Central Natural Science Collection ProQuest One ProQuest Central Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest Research Library SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Biological Sciences ProQuest Health & Medical Collection Research Library Biological Science Database Research Library (Corporate) ProQuest Central Premium ProQuest One Academic (New) Publicly Available Content Database ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) One Applied & Life Sciences ProQuest One Academic (retired) ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals
DatabaseTitle	CrossRef PubMed Publicly Available Content Database Research Library Prep ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College Research Library (Alumni Edition) ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Biological Science Collection ProQuest Research Library ProQuest Central (New) ProQuest Biological Science Collection ProQuest Central Basic ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest One Academic UKI Edition ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic
DatabaseTitleList	MEDLINE - Academic Publicly Available Content Database PubMed
Database_xml	– sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: PIMPY name: Publicly Available Content Database url: http://search.proquest.com/publiccontent sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine
DocumentTitleAlternate	Waziri et al
EISSN	1178-7058
EndPage	276
ExternalDocumentID	oai_doaj_org_article_96845d2de8034e37be7c893890d80ea4 PMC6935280 A611548920 31920363 10_2147_IJNRD_S191156
Genre	Journal Article Review
GroupedDBID	--- 0YH 29J 2WC 53G 5VS 7X7 8FE 8FH 8FI 8FJ 8G5 AAYXX ABUWG ADBBV ADRAZ AFFHD AFKRA ALMA_UNASSIGNED_HOLDINGS AOIJS AQTUD AZQEC BAWUL BBNVY BCNDV BENPR BHPHI BPHCQ BVXVI CCPQU CITATION DIK DWQXO E3Z EBD FYUFA GNUQQ GROUPED_DOAJ GUQSH GX1 HCIFZ HMCUK HYE IAO IHR IHW IPNFZ ITC KQ8 LK8 M2O M48 M7P M~E O5R O5S OK1 P2P PGMZT PHGZM PHGZT PIMPY PQGLB PQQKQ PROAC RIG RPM TDBHL TR2 UKHRP VDV ALIPV NPM 3V. 7XB 8FK K9. MBDVC PJZUB PKEHL PPXIY PQEST PQUKI PRINS Q9U 7X8 PUEGO 5PM
ID	FETCH-LOGICAL-c645t-e4555e111a013d0b65d54b331a9524c2c082add0f3e3c7f0382f8801d3fd66b33
IEDL.DBID	DOA
ISICitedReferencesCount	95
ISICitedReferencesURI	http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000504220800001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
ISSN	1178-7058
IngestDate	Tue Oct 14 19:05:56 EDT 2025 Tue Nov 04 01:34:52 EST 2025 Thu Oct 02 07:47:35 EDT 2025 Tue Oct 07 07:11:31 EDT 2025 Tue Nov 11 10:02:33 EST 2025 Tue Nov 04 18:05:41 EST 2025 Thu May 22 21:23:48 EDT 2025 Thu Apr 03 06:59:41 EDT 2025 Sat Nov 29 05:58:41 EST 2025 Tue Nov 18 21:30:59 EST 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Keywords	updated pathogenesis management emerging trends chronic kidney disease–mineral and bone disorder
Language	English
License	http://creativecommons.org/licenses/by-nc/3.0 2019 Waziri et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c645t-e4555e111a013d0b65d54b331a9524c2c082add0f3e3c7f0382f8801d3fd66b33
Notes	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23
ORCID	0000-0003-2750-2062 0000-0001-6291-6610 0000-0002-7058-9725
OpenAccessLink	https://doaj.org/article/96845d2de8034e37be7c893890d80ea4
PMID	31920363
PQID	2340008298
PQPubID	3933143
PageCount	14
ParticipantIDs	doaj_primary_oai_doaj_org_article_96845d2de8034e37be7c893890d80ea4 pubmedcentral_primary_oai_pubmedcentral_nih_gov_6935280 proquest_miscellaneous_2336254163 proquest_journals_2340008298 gale_infotracmisc_A611548920 gale_infotracacademiconefile_A611548920 gale_healthsolutions_A611548920 pubmed_primary_31920363 crossref_citationtrail_10_2147_IJNRD_S191156 crossref_primary_10_2147_IJNRD_S191156
PublicationCentury	2000
PublicationDate	2019-12
PublicationDateYYYYMMDD	2019-12-01
PublicationDate_xml	– month: 12 year: 2019 text: 2019-12
PublicationDecade	2010
PublicationPlace	New Zealand
PublicationPlace_xml	– name: New Zealand – name: Macclesfield
PublicationTitle	International journal of nephrology and renovascular disease
PublicationTitleAlternate	Int J Nephrol Renovasc Dis
PublicationYear	2019
Publisher	Dove Medical Press Limited Taylor & Francis Ltd Dove Dove Medical Press
Publisher_xml	– name: Dove Medical Press Limited – name: Taylor & Francis Ltd – name: Dove – name: Dove Medical Press
SSID	ssj0000396622
Score	2.4837477
SecondaryResourceType	review_article
Snippet	Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease-mineral and bone... Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease--mineral and bone... Despite the availability of global and regional guidelines to curtail the adverse clinical outcomes associated with chronic kidney disease–mineral and bone... Bala Waziri,1,2 Raquel Duarte,1 Saraladevi Naicker1 1Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand,...
SourceID	doaj pubmedcentral proquest gale pubmed crossref
SourceType	Open Website Open Access Repository Aggregation Database Index Database Enrichment Source
StartPage	263
SubjectTerms	Aluminum Biological markers Bone diseases Calcification Calcium phosphates chronic kidney disease-mineral and bone disorder Chronic kidney failure Clinical trials Drinking water emerging trends Endocrine system Fibroblast growth factor 23 Fibroblast growth factors Fibroblasts Fractures Growth factors Hemodialysis Hormones Hypotheses Kidney diseases management Metabolism Minerals Parathyroid Parathyroid hormone Parathyroid hormones Pathogenesis Phosphate binders Phosphates Review updated pathogenesis Vitamin D
SummonAdditionalLinks	– databaseName: Biological Science Database dbid: M7P link: http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3bbhMxELWgIMQL98tCASMhLhJLHdvr9fKCmoYKKImqFqS-Wbu2FyKhTUlSJN74B_6QL2HG62yzQvDCazwr2Znx8bE9PkPIIwEkpMqVTZmVLJVawZSqSpdqWwpWDUpYsYPO7Pt8MtFHR8V-PHBbxLTKFSYGoHYzi2fkW1zI9iGofnX8NcWqUXi7GktonCXnUCWBh9S9_e6MhQkg85y30ppYkGfr7bvJwejFIWxSBliyem0pCor9f-Ly2sLUT5pcW4V2L_9v_6-QS5F_0u02YK6SM765Ri6M4w37dXIQ1XLp3tQ1_jsdtRc4v378HE-DQDUtG0eHs8bTlXAnfbqzN0rHw9GzlzTKPdH90zecixvk4-7rDztv0lh3IbVKZsvUyyzLPIBgCfzQsUplLpOVEIOyyLi03MIwABZZLbywec2E5jXAwMCJ2ikFhjfJRgP9uE0oZw74h7UVV17WnlfAd0TO6tzCPiX3NiHPVy4wNoqSY22MLwY2J-gxEzxmoscS8rgzP27VOP5mOER_dkYooh1-mM0_mTgnTaG0zBx3XjMhvcgrn1ugb7pgTjNfyoQ8wGgw7YvUDgrMtkINI11wlpAnwQLBALpty_imAQaPslo9y82eJUxi229eRY2JILIwpyGTkIddM36JiXGNn52gDTCQDFl1Qm61AdoNGtAVr5mhJe-Fbu9f6bc0089BYlwVqPrD7vy7W3fJReCPRZvds0k2lvMTf4-ct9-W08X8fpiLvwH-XDq7 priority: 102 providerName: ProQuest
Title	Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD): Current Perspectives
URI	https://www.ncbi.nlm.nih.gov/pubmed/31920363 https://www.proquest.com/docview/2340008298 https://www.proquest.com/docview/2336254163 https://pubmed.ncbi.nlm.nih.gov/PMC6935280 https://doaj.org/article/96845d2de8034e37be7c893890d80ea4
Volume	12
WOSCitedRecordID	wos000504220800001&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
journalDatabaseRights	– providerCode: PRVAON databaseName: DOAJ Directory of Open Access Journals customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: DOA dateStart: 20080101 isFulltext: true titleUrlDefault: https://www.doaj.org/ providerName: Directory of Open Access Journals – providerCode: PRVHPJ databaseName: ROAD: Directory of Open Access Scholarly Resources customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: M~E dateStart: 20080101 isFulltext: true titleUrlDefault: https://road.issn.org providerName: ISSN International Centre – providerCode: PRVPQU databaseName: Biological Science Database customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: M7P dateStart: 20080101 isFulltext: true titleUrlDefault: http://search.proquest.com/biologicalscijournals providerName: ProQuest – providerCode: PRVPQU databaseName: Health & Medical Collection customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: 7X7 dateStart: 20080101 isFulltext: true titleUrlDefault: https://search.proquest.com/healthcomplete providerName: ProQuest – providerCode: PRVPQU databaseName: ProQuest Central customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: BENPR dateStart: 20080101 isFulltext: true titleUrlDefault: https://www.proquest.com/central providerName: ProQuest – providerCode: PRVPQU databaseName: Publicly Available Content Database customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: PIMPY dateStart: 20080101 isFulltext: true titleUrlDefault: http://search.proquest.com/publiccontent providerName: ProQuest – providerCode: PRVPQU databaseName: Research Library customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: M2O dateStart: 20080101 isFulltext: true titleUrlDefault: https://search.proquest.com/pqrl providerName: ProQuest – providerCode: PRVAWR databaseName: Taylor & Francis Open Access customDbUrl: eissn: 1178-7058 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0000396622 issn: 1178-7058 databaseCode: 0YH dateStart: 20081201 isFulltext: true titleUrlDefault: https://www.tandfonline.com providerName: Taylor & Francis
link	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3di9QwEB_0FPFF_LZ6rhXED7BcmrRJ6tvt7R2e567l9GB9Km2SYkV6srsn-N87Sbq1RcQXX_LQmUIymU-S_AbgGcMkpBJcRUQlJEokR5OqSh1JVTJSxSVGbIcz-14sFnK5zPJBqy97J8zDA3vB7WVcJqmm2kjCEsNEZYTCGCszoiUxpUMCJSIbFFPOBzNM490RQhxjmSRIKj3Apm3Ls9d8bVfonLBUiW3j6kFAcrj9f3rnQXgaX50cxKKjm3CjSyLDfT_5W3DJtLfh2rw7Jr8DeQd5G540ujU_w5k_hYnmjcOYDstWh9Pz1oRb7M3w5cHJLJpPZ6_ehB1iU5j_foa5vgtnR4efDt5GXeuESPEk3UQmSdPUoB8rMcXTpOKpTpOKsbjMUpooqjDyo2cjNTNMiZowSWu05FizWnOOjPdgp8V5PICQEo0phFIV5SapDa0wZWGC1EJhqSGMCuD1Vn6F6nDFbXuLbwXWF1bcxfG7xems-OjFHcDznv27B9T4G-PUbkbPZHGw3QfUjqLTjuJf2hHAE7uVhX9U2ltzsc8tDJHMKAngheOw9ozTVmX3LAEXb5GxRpy7I060QzUmb9Wl6PzAuqAs8c-XZQBPe7L9095ta835heXBJCK1iXEA97129YtGB2lPipEiRno3ksqY0jZfHEo4zyxwD3n4P8T4CK5jopj5azy7sLNZXZjHcFX92DTr1QQui6Vwo5zAlenhIj-dOHPEcU4_2FHkSMmP5_nnX9e3NBk
linkProvider	Directory of Open Access Journals
linkToHtml	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V1bb9MwFLamDgEv3C-BwYLEZUgLc23nhoTQujKt9KJqDGl7MontQCWUjrYD7Y3_wP_gR_FLOCdxskYI3vbAa32i2sl3brbPdwh5zCEIScNAeVQJ6okoAJVKE-1FKuE0bSfgsQue2UE4GkWHh_F4hfysamHwWmVlEwtDracK98i3GBdlIWj0-viLh12j8HS1aqFRwqJvTr9ByjZ_1evC933C2O6bg509z3YV8FQg_IVnhO_7BlQ8gehH0zTwtS9SzttJ7DOhmII_AaWnGTdchRnlEcsA5G3NMx0EKW6AgslfFQj2Flkd94bjo3pXh3JIHxgryTyxBdBW7-1ov_viHaRFbWySveT8ih4Bf3qCJVfYvKa55Pd2r_5vb-wauWIjbHe7VInrZMXkN8jFob1DcJPsWz5gtz_RuTl1u-UR1a_vP4aTgoLbTXLtdqa5cStqUndjp9_1hp3u85euJbRyx2dVqvNb5P25rOg2aeUwj7vEZVRDhKVUygIjMsNSiOh4SLNQQSYWGuWQzeqTS2Vp17H7x2cJ6RciRBYIkRYhDnlaix-XfCN_E-wgfmohpAkvfpjOPkprdWQcRMLXTJuIcmF4mJpQQYAaxVRH1CTCIeuIPlnW3NbGTm4HyNIUxYw65FkhgeYOpq0SW7UBi0fisIbkWkMSzJRqDlcoldZMzuUZRB3yqB7GJ_HqX26mJygDMZaPeYND7pQKUS8a_AcepMNI2FCVxltpjuSTTwWJehAjrxG99-9prZNLewfDgRz0Rv375DJEy3F5l2mNtBazE_OAXFBfF5P57KG1BC75cN6q9Buj3pdc
linkToPdf	http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMw1V3bbtNAEB1VLap44X4xFGokrhImm931DQmhpiYipImiFqTytNi7a4iEnJKkoL7xD_wNn8OXMGuv3VgI3vrAa3as7NozZ2Z2Z88A3GcYhGRhID0iOfF4FKBJZanyIpkyknVT9Nglz-xeOB5Hh4fxZA1-1ndhTFlljYklUKuZNHvkHcp4dRE06uS2LGKS9F8effFMBylz0lq306hUZKhPvmH6tngxSPBbP6C0_-rt7mvPdhjwZMD9pae57_sazT3FSEiRLPCVzzPGumnsUy6pxD9EACA500yGOWERzVHhu4rlKggysxmK8L-BITmn67AxGYwm75sdHsIwlaC0IvY07YA6gzfj_eTZAaZIXdMwe8URlv0C_vQKK26xXbK54gP7F__nt3cJLtjI292pTOUyrOniCmyObG3BVdi3PMHucKoKfeIm1dHVr-8_RtOSmttNC-X2ZoV2a8pS9_HuMPFGveTJc9cSXbmT09uri2vw7kxWdB3WC5zHTXApURh5SZnRQPNc0wwjPRaSPJSYoYVaOvC0_vxCWjp20xXks8C0zGiLKLVFWG1x4GEjflTxkPxNsGd0qREy9OHlD7P5R2HRSMRBxH1FlY4I45qFmQ4lBq5RTFREdMod2DaaKKq7uA0Iip3AsDdFMSUOPColDAzitGVqb3Pg4g2hWEtyqyWJ8CXbw7XGCgufC3Gqrg7ca4bNk6YksNCzYyODsZdv8gkHblTG0Swa_Yo5YMeRsGU2rbfSHimmn0py9SA2fEfk1r-ntQ2baD9ibzAe3obzGETHVYnTFqwv58f6DpyTX5fTxfyuBQUXPpy1Jf0GCzugHA
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Chronic+Kidney+Disease-Mineral+and+Bone+Disorder+%28CKD-MBD%29%3A+Current+Perspectives&rft.jtitle=International+journal+of+nephrology+and+renovascular+disease&rft.au=Waziri+B&rft.au=Duarte+R&rft.au=Naicker+S&rft.date=2019-12-01&rft.pub=Dove+Medical+Press&rft.issn=1178-7058&rft.eissn=1178-7058&rft.volume=12&rft.spage=263&rft.epage=276&rft_id=info:doi/10.2147%2Fijnrd.s191156&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_96845d2de8034e37be7c893890d80ea4
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1178-7058&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1178-7058&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1178-7058&client=summon