Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine
Purpose To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. Methods A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed...
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| Published in: | Intensive care medicine Vol. 47; no. 12; pp. 1368 - 1392 |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , |
| Format: | Journal Article |
| Language: | English |
| Published: |
Berlin/Heidelberg
Springer Berlin Heidelberg
01.12.2021
Springer Springer Nature B.V |
| Subjects: | |
| ISSN: | 0342-4642, 1432-1238, 1432-1238 |
| Online Access: | Get full text |
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| Abstract | Purpose
To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.
Methods
A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format.
Results
The taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation.
Conclusions
This clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed. |
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| AbstractList | PurposeTo develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.MethodsA taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format.ResultsThe taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation.ConclusionsThis clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed. Purpose To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. Methods A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. Results The taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation. Conclusions This clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed. Purpose To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. Methods A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. Results The taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation. Conclusions This clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed. To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. The taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation. This clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed. To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format. The taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation. This clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed. To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.PURPOSETo develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.A taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format.METHODSA taskforce involving 15 international experts and 2 methodologists used the GRADE approach to guideline development. The taskforce addressed three main topics: transfusion support in massively and non-massively bleeding critically ill patients (transfusion ratios, blood products, and point of care testing) and the use of tranexamic acid. The panel developed and answered structured guideline questions using population, intervention, comparison, and outcomes (PICO) format.The taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation.RESULTSThe taskforce generated 26 clinical practice recommendations (2 strong recommendations, 13 conditional recommendations, 11 no recommendation), and identified 10 PICOs with insufficient evidence to make a recommendation.This clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed.CONCLUSIONSThis clinical practice guideline provides evidence-based recommendations for the management of massively and non-massively bleeding critically ill adult patients and identifies areas where further research is needed. |
| Audience | Academic |
| Author | Aubron, Cecile Vlaar, Alexander P. J. Juffermans, Nicole P. Hunt, Beverley J. Schöchl, Herbert Nielsen, Nathan D. Dionne, Joanna C. Duranteau, Jacques Müller, Marcella C. A. Cecconi, Maurizio de Bruin, Sanne Oczkowski, Simon Wijnberge, Marije van Baarle, Frank E. H. P. Murphy, Gavin J. Raasveld, S. Jorinde Antonelli, Massimo Meier, Jens Abbasciano, Riccardo Lance, Marcus |
| Author_xml | – sequence: 1 givenname: Alexander P. J. orcidid: 0000-0002-3453-7186 surname: Vlaar fullname: Vlaar, Alexander P. J. email: a.p.vlaar@amsterdamumc.nl organization: Department of Intensive Care Medicine, Amsterdam UMC, Location AMC – sequence: 2 givenname: Joanna C. surname: Dionne fullname: Dionne, Joanna C. organization: Department of Medicine, McMaster University, The Guidelines in Intensive Care Development and Evaluation (GUIDE) Group, He Research Institute St. Joseph’s Healthcare Hamilton, Department of Health Research Methods, Evidence, and Impact, McMaster University, Division of Gastroenterology, McMaster University – sequence: 3 givenname: Sanne surname: de Bruin fullname: de Bruin, Sanne organization: Department of Intensive Care Medicine, Amsterdam UMC, Location AMC – sequence: 4 givenname: Marije surname: Wijnberge fullname: Wijnberge, Marije organization: Department of Intensive Care Medicine, Amsterdam UMC, Location AMC, Department of Anaesthesiology, Amsterdam UMC, Location AMC – sequence: 5 givenname: S. Jorinde surname: Raasveld fullname: Raasveld, S. Jorinde organization: Department of Intensive Care Medicine, Amsterdam UMC, Location AMC – sequence: 6 givenname: Frank E. H. P. surname: van Baarle fullname: van Baarle, Frank E. H. P. organization: Department of Intensive Care Medicine, Amsterdam UMC, Location AMC – sequence: 7 givenname: Massimo surname: Antonelli fullname: Antonelli, Massimo organization: Department of Anaesthesiology and Intensive Care Medicine, Fondazione Policlinico Universitario A.Gemelli IRCCS, Istituto di Anaesthesiology e Rianimazione Università Cattolica del Sacro Cuore – sequence: 8 givenname: Cecile surname: Aubron fullname: Aubron, Cecile organization: Department of Intensive Care Medicine, Centre Hospitalier Régional et Universitaire de Brest, site La Cavale Blanche, Université de Bretagne Occidentale – sequence: 9 givenname: Jacques surname: Duranteau fullname: Duranteau, Jacques organization: Department of Anaesthesia and Intensive Care, Hôpitaux Universitaires Paris Sud (HUPS) – sequence: 10 givenname: Nicole P. surname: Juffermans fullname: Juffermans, Nicole P. organization: Laboratory of Experimental Intensive Care and Anesthesiology, Amsterdam University Medical Center, OLVG Hospital – sequence: 11 givenname: Jens surname: Meier fullname: Meier, Jens organization: Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Kepler University – sequence: 12 givenname: Gavin J. surname: Murphy fullname: Murphy, Gavin J. organization: NIHR Leicester Biomedical Research Centre–Cardiovascular, Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester – sequence: 13 givenname: Riccardo surname: Abbasciano fullname: Abbasciano, Riccardo organization: NIHR Leicester Biomedical Research Centre–Cardiovascular, Department of Cardiovascular Sciences, College of Life Sciences, University of Leicester – sequence: 14 givenname: Marcella C. A. surname: Müller fullname: Müller, Marcella C. A. organization: Department of Intensive Care Medicine, Amsterdam UMC, Location AMC – sequence: 15 givenname: Marcus surname: Lance fullname: Lance, Marcus organization: Department of Anesthesiology, Intensive Care and Perioperative Medicine, Hamad Medical Corporation – sequence: 16 givenname: Nathan D. surname: Nielsen fullname: Nielsen, Nathan D. organization: Division of Pulmonary, Critical Care, and Sleep Medicine, University of New Mexico School of Medicine – sequence: 17 givenname: Herbert surname: Schöchl fullname: Schöchl, Herbert organization: Department of Anaesthesiology and Intensive Care Medicine, AUVA Trauma Centre Salzburg, Academic Teaching Hospital of the Paracelsus Medical University, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, AUVA Trauma Research Centre – sequence: 18 givenname: Beverley J. surname: Hunt fullname: Hunt, Beverley J. organization: Thrombosis and Haemophilia Centre, Guys & St Thomas’ NHS Foundation Trust – sequence: 19 givenname: Maurizio surname: Cecconi fullname: Cecconi, Maurizio organization: Department of Anaesthesia and Intensive Care Medicine, Humanitas Clinical and Research Centre-IRCCS, Humanitas University – sequence: 20 givenname: Simon surname: Oczkowski fullname: Oczkowski, Simon organization: Department of Medicine, McMaster University, The Guidelines in Intensive Care Development and Evaluation (GUIDE) Group, He Research Institute St. Joseph’s Healthcare Hamilton, Department of Health Research Methods, Evidence, and Impact, McMaster University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/34677620$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1007/s00134-019-05884-8 10.3310/pgfar05170 10.1007/s00134-020-06279-w 10.1001/jama.2019.17312 10.1111/jth.12078 10.1016/j.clineuro.2015.06.007 10.1056/NEJMoa1211801 10.1161/JAHA.115.002066 10.1093/icvts/ivs224 10.1016/j.jclinepi.2010.09.012 10.1136/bmj.1.6118.945 10.3109/00365527909181413 10.1016/j.jclinepi.2011.01.012 10.1016/S0140-6736(10)61479-1 10.1093/bja/aew169 10.1001/jama.2016.21037 10.1056/NEJMoa1606424 10.1111/trf.15917 10.1016/j.bja.2018.02.017 10.1016/j.jamcollsurg.2012.10.017 10.1016/S0140-6736(11)60317-6 10.2741/1715 10.1136/bmj.a744 10.1016/j.ajem.2018.02.018 10.1016/S0140-6736(73)90525-4 10.1016/S1474-4422(20)30369-0 10.1001/jama.2020.8958 10.1016/S2352-3026(17)30077-7 10.1016/S0140-6736(19)32233-0 10.1053/j.jvca.2019.06.030 10.1093/bja/aew343 10.1016/j.bja.2020.04.087 10.1111/tme.12022 10.1016/S0140-6736(18)31033-X 10.1097/CCM.0000000000002498 10.1186/cc10143 10.1186/s13054-018-2086-x 10.1016/S0140-6736(14)61999-1 10.1007/BF01402177 10.1016/j.jstrokecerebrovasdis.2013.11.007 10.1097/ALN.0b013e3182715d4d 10.1002/ana.410020311 10.1136/bmj.39489.470347.AD 10.1016/S0140-6736(16)30392-0 10.1016/j.ijoa.2018.08.001 10.1093/bja/aex100 10.1016/j.injury.2010.11.003 10.1186/s13643-016-0384-4 10.1097/SLA.0000000000001608 10.1016/j.jclinepi.2011.03.017 10.1213/ANE.0000000000001926 10.3171/jns.2002.97.4.0771 10.1111/trf.12248 10.1111/1471-0528.12531 10.1007/s00134-013-3044-3 10.1136/tsaco-2016-000056 10.1002/9781119536604 10.1097/DCR.0000000000000943 10.1001/jama.2015.12 10.1371/journal.pone.0018987 10.1001/jamasurg.2017.0098 10.1016/j.tmrv.2017.06.003 10.1055/s-0037-1599103 10.1186/cc13798 10.1089/neu.2014.3728 10.1177/2050640617714940 10.1186/s13054-019-2591-6 10.1016/j.jclinepi.2010.07.017 10.1056/NEJM198408163110703 10.1002/ana.410030607 10.1097/MBC.0000000000000777 10.1002/hep.30794 10.3109/03009738009179185 10.1182/blood-2018-10-877530 10.1186/s13613-017-0341-y 10.1111/trf.15177 10.1111/j.1423-0410.2011.01575.x 10.1016/S0140-6736(20)32518-6 10.1016/j.hlc.2018.10.025 10.1227/00006123-198102000-00004 10.1161/01.STR.10.5.519 10.1136/bmj.294.6563.7 10.1093/bja/aet376 10.1213/ANE.0000000000000689 10.1097/SHK.0000000000000918 10.1056/NEJM198306303082606 10.1097/ALN.0000000000003550 10.1016/S0140-6736(20)30848-5 10.1111/anae.14495 10.5604/01.3001.0010.5283 10.1503/cmaj.121986 10.1186/s13054-015-1172-6 10.1016/S0140-6736(17)30638-4 10.1186/s13054-017-1745-7 10.1002/bjs.1800731007 10.1016/j.jclinepi.2011.04.014 10.1097/MCG.0000000000001214 |
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| ISSN | 0342-4642 1432-1238 |
| IngestDate | Tue Nov 04 01:46:29 EST 2025 Fri Sep 05 14:32:48 EDT 2025 Wed Nov 05 03:11:02 EST 2025 Sat Nov 29 13:22:54 EST 2025 Sat Nov 29 11:17:13 EST 2025 Sat Nov 29 10:02:11 EST 2025 Mon Jul 21 06:03:15 EDT 2025 Sat Nov 29 05:59:46 EST 2025 Tue Nov 18 22:18:57 EST 2025 Fri Feb 21 02:47:06 EST 2025 |
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| Issue | 12 |
| Keywords | Plasma Intensive care Transfusion Red blood cells Critically ill Point of care Tranexamic acid Guideline Platelets Coagulopathy Bleeding |
| Language | English |
| License | 2021. The Author(s). Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/. |
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| OpenAccessLink | https://link.springer.com/10.1007/s00134-021-06531-x |
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| PublicationPlace | Berlin/Heidelberg |
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| PublicationTitle | Intensive care medicine |
| PublicationTitleAbbrev | Intensive Care Med |
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| PublicationYear | 2021 |
| Publisher | Springer Berlin Heidelberg Springer Springer Nature B.V |
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| References | Inaba, Karamanos, Lustenberger, Schöchl, Shulman, Nelson, Rhee, Talving, Lam, Demetriades (CR41) 2013; 216 Guyatt, Oxman, Vist, Kunz, Falck-Ytter, Alonso-Coello, Schunemann (CR7) 2008; 336 Jairath, Kahan, Gray, Doré, Mora, James, Stanley, Everett, Bailey, Dallal, Greenaway, Le Jeune, Darwent, Church, Reckless, Hodge, Dyer, Meredith, Llewelyn, Palmer, Logan, Travis, Walsh, Murphy (CR50) 2015; 386 van Rossum, Wintzen, Endtz, Schoen, de Jonge (CR93) 1977; 2 Roman, Abbasciano, Pathak, Oo, Yusoff, Wozniak, Qureshi, Lai, Kumar, Richards, Yao, Estcourt, Murphy (CR76) 2021; 126 Post, Germans, Tjerkstra, Vergouwen, Jellema, Koot, Kruyt, Willems, Wolfs, de Beer, Kieft, Nanda, van der Pol, Roks, de Beer, Halkes, Reichman, Brouwers, van den Berg-Vos, Kwa, van der Ree, Bronner, van de Vlekkert, Bienfait, Boogaarts, Klijn, van den Berg, Coert, Horn, Majoie, Rinkel, Roos, Vandertop, Verbaan, Post, Germans, Tjerkstra, Vergouwen, Jellema, Koot, Kruyt, Willems, Wolfs, de Beer, Kieft, Nanda, van der Pol, Roks, de Beer, Halkes, Reichman, Brouwers, van den Berg-Vos, Kwa, van der Ree, Bronner, Bienfait, Boogaarts, Klijn, van Bilzen, Dieks, de Gans, ten Holter, de Kruijk, Leijzer, Molenaar, van Oostenbrugge, van Pamelen, Spaander, Vermeer, van de Vlekkert, Voorend, van den Berg, Coert, Horn, Majoie, Rinkel, Roos, Vandertop, Verbaan (CR90) 2021; 397 Jaeschke, Guyatt, Dellinger, Schunemann, Levy, Kunz, Norris, Bion (CR18) 2008; 337 Chang, Holcomb, Johansson, Pati, Schreiber, Wade (CR66) 2018; 49 Sprigg, Flaherty, Appleton, Al-Shahi Salman, Bereczki, Beridze, Christensen, Ciccone, Collins, Czlonkowska, Dineen, Duley, Egea-Guerrero, England, Krishnan, Laska, Law, Ozturk, Pocock, Roberts, Robinson, Roffe, Seiffge, Scutt, Thanabalan, Werring, Whynes, Bath, Investigators (CR97) 2018; 391 Murphy, Mumford, Rogers, Wordsworth, Stokes, Verheyden, Kumar, Harris, Clayton, Ellis, Plummer, Dott, Serraino, Wozniak, Morris, Nath, Sterne, Angelini, Reeves (CR75) 2017 Collaborators (CR98) 2020; 395 Baharoglu, Cordonnier, Salman, de Gans, Koopman, Brand, Majoie, Beenen, Marquering, Vermeulen, Nederkoorn, de Haan, Roos (CR53) 2016; 387 Prick, Jansen, Steegers, Hop, Essink-Bot, Uyl-de Groot, Akerboom, van Alphen, Bloemenkamp, Boers, Bremer, Kwee, van Loon, Metz, Papatsonis, van der Post, Porath, Rijnders, Roumen, Scheepers, Schippers, Schuitemaker, Stigter, Woiski, Mol, van Rhenen, Duvekot (CR45) 2014; 121 Holcomb, Tilley, Baraniuk, Fox, Wade, Podbielski, del Junco, Brasel, Bulger, Callcut, Cohen, Cotton, Fabian, Inaba, Kerby, Muskat, Keeffe, Rizoli, Robinson, Scalea, Schreiber, Stein, Weinberg, Callum, Hess, Matijevic, Miller, Pittet, Hoyt, Pearson, Leroux, van Belle (CR20) 2015; 313 (CR107) 2017; 389 Chandra (CR85) 1978; 3 Nascimento, Callum, Tien, Rubenfeld, Pinto, Lin, Rizoli (CR21) 2013; 185 Consunji, Elseed, El-Menyar, Sathian, Rizoli, Al-Thani, Peralta (CR28) 2020; 18 Cormack, Jouhar (CR103) 1973; 1 Roberts, Shakur, Afolabi, Brohi, Coats, Dewan, Gando, Guyatt, Hunt, Morales, Perel, Prieto-Merino, Woolley (CR81) 2011; 377 Tsementzis, Hitchcock, Meyer (CR92) 1990; 102 Vlaar, Oczkowski, de Bruin, Wijnberge, Antonelli, Aubron, Aries, Duranteau, Juffermans, Meier, Murphy, Abbasciano, Muller, Shah, Perner, Rygaard, Walsh, Guyatt, Dionne, Cecconi (CR6) 2020 Lance, Ninivaggi, Schols, Feijge, Oehrl, Kuiper, Nikiforou, Marcus, Hamulyak, van Pampus, ten Cate, Heemskerk (CR63) 2012; 103 Lisman, Weeterings, de Groot (CR55) 2005; 10 Arnekian, Camous, Fattal, Rezaiguia-Delclaux, Nottin, Stephan (CR31) 2012; 15 Curry, Foley, Wong, Mora, Curnow, Zarankaite, Hodge, Hopkins, Deary, Ray, Moss, Reed, Kellett, Davenport, Stanworth (CR37) 2018; 22 Tanaka, Egan, Szlam, Ogawa, Roback, Sreeram, Guyton, Chen (CR62) 2014; 54 Maurice-Williams (CR89) 1978; 1 Russell, Holst, Kjeldsen, Stensballe, Perner (CR3) 2017; 7 Biancari, Ruggieri, Perrotti, Gherli, Demal, Franzese, Dalen, Santarpino, Rubino, Maselli, Salsano, Nicolini, Saccocci, Gatti, Rosato, D'Errigo, Kinnunen, De Feo, Tauriainen, Onorati, Mariscalco (CR32) 2019; 28 von Holstein, Eriksson, Kallen (CR102) 1987; 294 Mesar, Larentzakis, Dzik, Chang, Velmahos, Yeh (CR23) 2017; 152 Russell, Haase, Perner (CR2) 2018; 29 Guyatt, Oxman, Kunz, Atkins, Brozek, Vist, Alderson, Glasziou, Falck-Ytter, Schunemann (CR8) 2011; 64 Torres, Chung, Salgado, Dubick, Torres Filho (CR65) 2017; 21 Barer, Ogilvie, Henry, Dronfield, Coggon, French, Ellis, Atkinson, Langman (CR99) 1983; 308 Wirtz, Schalkers, Goslings, Juffermans (CR43) 2020; 60 Dutta, Poole, Behnia, Dunn, Clark, Pacheco, Saade, Hankins (CR26) 2017; 34 Bergqvist, Dahlgren, Hessman (CR104) 1980; 85 Weiniger, Yakirevich-Amir, Sela, Gural, Ioscovich, Einav (CR27) 2018; 36 Guyatt, Oxman, Vist, Kunz, Brozek, Alonso-Coello, Montori, Akl, Djulbegovic, Falck-Ytter, Norris, Williams, Atkins, Meerpohl, Schunemann (CR14) 2011; 64 Pham, Shaz (CR4) 2013; 111 Fodstad, Forssell, Liliequist, Schannong (CR86) 1981; 8 Bohonek, Kutac, Landova, Koranova, Sladkova, Staskova, Voldrich, Tyll (CR29) 2019; 59 (CR78) 2019; 394 Ducloy-Bouthors, Jude, Duhamel, Broisin, Huissoud, Keita-Meyer, Mandelbrot, Tillouche, Fontaine, Le Goueff, Depret-Mosser, Vallet, Susen (CR108) 2011; 15 Raza, Davenport, Rourke, Platton, Manson, Spoors, Khan, De'Ath, Allard, Hart, Pasi, Hunt, Stanworth, MacCallum, Brohi (CR80) 2013; 11 Strandenes, Sivertsen, Bjerkvig, Fosse, Cap, Del Junco, Kristoffersen, Haaverstad, Kvalheim, Braathen, Lunde, Hervig, Hufthammer, Spinella, Apelseth (CR30) 2020; 133 Mavrides, Allard, Chandraharan, Collins, Green, Hunt, Riris, Thompson (CR47) 2017 Smart, Mumtaz, Scharpf, Gray, Traetow, Black, Michaels, Elkhammas, Kirkpatrick, Hanje (CR70) 2017; 16 Kumar, Ahmad, Maiwall, Choudhury, Bajpai, Mitra, Saluja, Mohan Agarwal, Bihari, Shasthry, Jindal, Bhardwaj, Kumar, Sarin (CR67) 2020; 71 Villanueva, Colomo, Bosch, Concepcion, Hernandez-Gea, Aracil, Graupera, Poca, Alvarez-Urturi, Gordillo, Guarner-Argente, Santalo, Muniz, Guarner (CR48) 2013; 368 McQuilten, Crighton, Brunskill, Morison, Richter, Waters, Murphy, Wood (CR19) 2018; 32 Lawati, Sharif, Maqbali, Rimawi, Petrosoniak, Belley-Cote, Sharma, Morgenstern, Fernando, Owen, Zeller, Quinlan, Alhazzani, Rochwerg (CR83) 2020 Rahe-Meyer, Solomon, Hanke, Schmidt, Knoerzer, Hochleitner, Sorensen, Hagl, Pichlmaier (CR59) 2013; 118 Lauzier, Arnold, Rabbat, Heels-Ansdell, Zarychanski, Dodek, Ashley, Albert, Khwaja, Ostermann, Skrobik, Fowler, McIntyre, Nates, Karachi, Lopes, Zytaruk, Finfer, Crowther, Cook (CR1) 2013; 39 de Bruin, Scheeren, Bakker, van Bruggen, Vlaar (CR5) 2019; 23 Ouzzani, Hammady, Fedorowicz, Elmagarmid (CR9) 2016; 5 Blair, Janvrin, Mccollum, Greenhalgh (CR49) 1986; 73 Villarejo, Rizzolo, Lopez, Domeniconi, Atro, Apezteguia (CR51) 1999; 29 Nascimento, Callum, Tien, Peng, Rizoli, Karanicolas, Alam, Xiong, Selby, Garzon, Colavecchia, Howald, Nathens, Beckett (CR39) 2016; 117 Napolitano (CR82) 2017; 2 Fitzgerald, Lenihan, Callum, McCluskey, Srinivas, van Rensburg, Karkouti (CR34) 2018; 120 Meco, Montisci, Giustiniano, Greco, Pappalardo, Mammana, Panisi, Roscitano, Cirri, Donatelli, Albano (CR72) 2020; 34 Buscher, Zhang, Nair (CR74) 2017; 19 Engel-Haber, Horev, Chablani, Bornstein, Jadhav, Jovin, Reddy, Hammer (CR52) 2015; 137 Rowell, Meier, McKnight, Kannas, May, Sheehan, Bulger, Idris, Christenson, Morrison, Frascone, Bosarge, Colella, Johannigman, Cotton, Callum, McMullan, Dries, Tibbs, Richmond, Weisfeldt, Tallon, Garrett, Zielinski, Aufderheide, Gandhi, Schlamp, Robinson, Jui, Klein, Rizoli, Gamber, Fleming, Hwang, Vincent, Williams, Hendrickson, Simonson, Klotz, Sopko, Witham, Ferrara, Schreiber (CR84) 2020; 324 Myles, Smith, Painter (CR109) 2017; 376 Tavakoli, Mokhtare, Agah, Azizi, Masoodi, Amiri, Sheikhvatan, Syedsalehi, Behnam, Arabahmadi, Mehrazi (CR101) 2018; 6 Esmaeelzadeh, Amini, Soltani, Abbasi Tashnizi, Azami (CR57) 2016; 4 Sprigg, Renton, Dineen, Kwong, Bath (CR96) 2014; 23 Innerhofer, Fries, Mittermayr, Innerhofer, von Langen, Hell, Gruber, Schmid, Friesenecker, Lorenz, Ströhle, Rastner, Trübsbach, Raab, Treml, Wally, Treichl, Mayr, Kranewitter, Oswald (CR38) 2017; 4 Moller, Nielsen, Wetterslev, Pedersen, Hellemann, Winkel, Marcussen, Ramsing, Mortensen, Jakobsen, Shahidi (CR44) 2019; 133 Sinha, Roxby, Bersten (CR24) 2013; 23 Peterson, Welch, Losos, Tugwell (CR11) 2011 Roos, Rinkel, Vermeulen, Algra, van Gijn (CR91) 2000 Gonzalez, Moore, Moore, Chapman, Chin, Ghasabyan, Wohlauer, Barnett, Bensard, Biffl, Burlew, Johnson, Pieracci, Jurkovich, Banerjee, Silliman, Sauaia (CR71) 2016; 263 Guerriero, Cairns, Perel, Shakur, Roberts (CR79) 2011; 6 Manager (CR12) 2014 Rout, Shalimar, Mahapatra, Kedia, Garg, Nayak (CR68) 2020; 54 Cornell, Localio, Stack, Meibohm, Guallar, Goodman (CR13) 2014; 160 Hagemo, Stanworth, Juffermans, Brohi, Cohen, Johansson, Røislien, Eken, Næss, Gaarder (CR42) 2014; 18 Floccard, Rugeri, Faure, Saint Denis, Boyle, Peguet, Levrat, Guillaume, Marcotte, Vulliez (CR40) 2012; 43 Engqvist, Brostrom, von Feilitzen, Halldin, Nystrom, Ost, Reichard, Sandqvist, Torngren, Wedlund (CR100) 1979; 14 Bilecen, de Groot, Kalkman, Spanjersberg, Brandon Bravo Bruinsma, Moons, Nierich (CR56) 2017; 317 Higgins, Thomas, Chandler, Cumpston, Li, Page, Welch (CR10) 2019 Akbari, Safari, Hatamabadi (CR36) 2018; 36 Kaste, Ramsay (CR88) 1979; 10 Kim, O'Leary, Nguyen, Kaji, Bricker, Neville, Bongard, Putnam, Plurad (CR54) 2015; 32 Smith, Murray, Pockney, Bendinelli, Draganic, Carroll (CR105) 2018; 61 Delaney, Stark, Suh, Triulzi, Hess, Steiner, Stowell, Sloan (CR25) 2017; 124 Green, Connolly, Cooper, Cho, Allard (CR46) 2015 Hillman, Fridriksson, Nilsson, Yu, Saveland, Jakobsson (CR87) 2002; 97 Callum, Farkouh, Scales, Heddle, Crowther, Rao, Hucke, Carroll, Grewal, Brar, Bussieres, Grocott, Harle, Pavenski, Rochon, Saha, Shepherd, Syed, Tran, Wong, Zeller, Karkouti (CR64) 2019 Meretoja, Yassi, Wu, Churilov, Sibolt, Jeng, Kleinig, Spratt, Thijs, Wijeratne, Cho, Shah, Cloud, Phan, Bladin, Moey, Aviv, Barras, Sharma, Hsu, Ma, Campbell, Mitchell, Yan, Parsons, Tiainen, Curtze, Strbian, Tang, Harvey, Levi, Donnan, Davis (CR95) 2020; 19 Rahe- N Rahe-Meyer (6531_CR59) 2013; 118 B Floccard (6531_CR40) 2012; 43 R Post (6531_CR90) 2021; 397 M Meco (6531_CR72) 2020; 34 KA Tanaka (6531_CR62) 2014; 54 G Cappabianca (6531_CR33) 2016; 20 J Fitzgerald (6531_CR34) 2018; 120 AP Vlaar (6531_CR6) 2020 G Strandenes (6531_CR30) 2020; 133 AS Ducloy-Bouthors (6531_CR108) 2011; 15 KS Gurusamy (6531_CR69) 2011 GA Morrison (6531_CR58) 2019; 74 SA Tsementzis (6531_CR92) 1990; 102 GH Guyatt (6531_CR7) 2008; 336 I Raza (6531_CR80) 2013; 11 B Nascimento (6531_CR39) 2016; 117 R Sinha (6531_CR24) 2013; 23 MA Roman (6531_CR76) 2021; 126 SR Smith (6531_CR105) 2018; 61 ZK McQuilten (6531_CR19) 2018; 32 M Bohonek (6531_CR29) 2019; 59 F Biancari (6531_CR32) 2019; 28 E Mavrides (6531_CR47) 2017 R Chang (6531_CR66) 2018; 49 GH Guyatt (6531_CR14) 2011; 64 E Ortmann (6531_CR35) 2015; 121 A Engqvist (6531_CR100) 1979; 14 R Manager (6531_CR12) 2014 J Peterson (6531_CR11) 2011 GH Guyatt (6531_CR17) 2011; 64 S Blair (6531_CR49) 1986; 73 F Lauzier (6531_CR1) 2013; 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| References_xml | – volume: 1 start-page: 1207 year: 1973 end-page: 1208 ident: CR103 article-title: Tranexamic acid in upper gastrointestinal haemorrhage publication-title: Lancet – start-page: CD009052 year: 2011 ident: CR69 article-title: Methods to decrease blood loss and transfusion requirements for liver transplantation publication-title: Cochrane database of systematic reviews – start-page: e106 year: 2017 end-page: e149 ident: CR47 publication-title: Prevention and management of postpartum haemorrhage: green-top guideline no. 52 – volume: 23 start-page: 309 year: 2019 ident: CR5 article-title: Transfusion practice in the non-bleeding critically ill: an international online survey-the TRACE survey publication-title: Crit Care – volume: 36 start-page: 1947 year: 2018 end-page: 1950 ident: CR36 article-title: The effect of fibrinogen concentrate and fresh frozen plasma on the outcome of patients with acute traumatic coagulopathy: a quasi-experimental study publication-title: Am J Emerg Med – volume: 118 start-page: 40 year: 2013 end-page: 50 ident: CR59 article-title: Effects of fibrinogen concentrate as first-line therapy during major aortic replacement surgery: a randomized, placebo-controlled trial publication-title: Anesthesiology – volume: 133 start-page: 1173 year: 2020 end-page: 1183 ident: CR30 article-title: A pilot trial of platelets stored cold versus at room temperature for complex cardiothoracic surgery publication-title: Anesthesiology – volume: 45 start-page: 1311 year: 2017 end-page: 1316 ident: CR22 article-title: Should all massively transfused patients be treated equally? An analysis of massive transfusion ratios in the nontrauma setting publication-title: Crit Care Med – volume: 28 start-page: 1881 year: 2019 end-page: 1887 ident: CR32 article-title: Comparative analysis of prothrombin complex concentrate and fresh frozen plasma in coronary surgery publication-title: Heart Lung Circ – volume: 29 start-page: 683 year: 2018 end-page: 688 ident: CR2 article-title: Prediction of bleeding by thromboelastography in ICU patients with haematological malignancy and severe sepsis publication-title: Blood Coagul Fibrinolysis – volume: 103 start-page: 25 year: 2012 end-page: 34 ident: CR63 article-title: Perioperative dilutional coagulopathy treated with fresh frozen plasma and fibrinogen concentrate: a prospective randomized intervention trial publication-title: Vox Sang – volume: 11 start-page: 307 year: 2013 end-page: 314 ident: CR80 article-title: The incidence and magnitude of fibrinolytic activation in trauma patients publication-title: J Thromb Haemost – volume: 34 start-page: 861 year: 2017 end-page: 866 ident: CR26 article-title: Hemostatic resuscitation in peripartum hysterectomy pre- and postmassive transfusion protocol initiation publication-title: Am J Perinatol – volume: 137 start-page: 12 year: 2015 end-page: 14 ident: CR52 article-title: Aspirin response test role in platelet transfusion following intracerebral hemorrhage publication-title: Clin Neurol Neurosurg – volume: 185 start-page: E583 year: 2013 end-page: 589 ident: CR21 article-title: Effect of a fixed-ratio (1:1:1) transfusion protocol versus laboratory-results-guided transfusion in patients with severe trauma: a randomized feasibility trial publication-title: CMAJ – volume: 3 start-page: 502 year: 1978 end-page: 504 ident: CR85 article-title: Treatment of subarachnoid hemorrhage from ruptured intracranial aneurysm with tranexamic acid: a double-blind clinical trial publication-title: Ann Neurol – year: 2019 ident: CR10 publication-title: Cochrane handbook for systematic reviews of interventions – volume: 6 start-page: 46 year: 2018 end-page: 54 ident: CR101 article-title: Comparison of the efficacy of intravenous tranexamic acid with and without topical administration versus placebo in urgent endoscopy rate for acute gastrointestinal bleeding: a double-blind randomized controlled trial publication-title: United Eur Gastroenterol J – volume: 111 start-page: i71 issue: Suppl 1 year: 2013 end-page: 82 ident: CR4 article-title: Update on massive transfusion publication-title: Br J Anaesth – volume: 133 start-page: 2639 year: 2019 end-page: 2650 ident: CR44 article-title: Low vs high hemoglobin trigger for transfusion in vascular surgery: a randomized clinical feasibility trial publication-title: Blood – volume: 21 start-page: 160 year: 2017 ident: CR65 article-title: Low-volume resuscitation with normal saline is associated with microvascular endothelial dysfunction after hemorrhage in rats, compared to colloids and balanced crystalloids publication-title: Crit Care – volume: 49 start-page: 53 year: 2018 end-page: 61 ident: CR66 article-title: Plasma resuscitation improved survival in a cecal ligation and puncture rat model of sepsis publication-title: Shock – volume: 85 start-page: 173 year: 1980 end-page: 178 ident: CR104 article-title: Local inhibition of the fibrinolytic system in patients with massive upper gastrointestinal hemorrhage publication-title: Upsala J Med Sci – start-page: CD001245 year: 2000 ident: CR91 article-title: Antifibrinolytic therapy for aneurysmal subarachnoid haemorrhage publication-title: Cochrane database system reviews – volume: 395 start-page: 1927 year: 2020 end-page: 1936 ident: CR98 article-title: Effects of a high-dose 24-h infusion of tranexamic acid on death and thromboembolic events in patients with acute gastrointestinal bleeding (HALT-IT): an international randomised, double-blind, placebo-controlled trial publication-title: Lancet – volume: 376 start-page: 1893 year: 2017 ident: CR109 article-title: Tranexamic acid in patients undergoing coronary-artery surgery publication-title: N Engl J Med – volume: 308 start-page: 1571 year: 1983 end-page: 1575 ident: CR99 article-title: Cimetidine and tranexamic acid in the treatment of acute upper-gastrointestinal-tract bleeding publication-title: N Engl J Med – volume: 4 start-page: e258 year: 2017 end-page: e271 ident: CR38 article-title: Reversal of trauma-induced coagulopathy using first-line coagulation factor concentrates or fresh frozen plasma (RETIC): a single-centre, parallel-group, open-label, randomised trial publication-title: Lancet Haematol – volume: 160 start-page: 267 year: 2014 end-page: 270 ident: CR13 article-title: Random-effects meta-analysis of inconsistent effects: a time for change publication-title: Ann Intern Med – volume: 64 start-page: 1303 year: 2011 end-page: 1310 ident: CR16 article-title: GRADE guidelines: 8. Rating the quality of evidence–indirectness publication-title: J Clin Epidemiol – volume: 317 start-page: 738 year: 2017 end-page: 747 ident: CR56 article-title: Effect of fibrinogen concentrate on intraoperative blood loss among patients with intraoperative bleeding during high-risk cardiac surgery: a randomized clinical trial publication-title: JAMA – volume: 60 start-page: 1873 year: 2020 end-page: 1882 ident: CR43 article-title: The impact of blood product ratio and procoagulant therapy on the development of thromboembolic events in severely injured hemorrhaging trauma patients publication-title: Transfusion – volume: 121 start-page: 1005 year: 2014 end-page: 1014 ident: CR45 article-title: Transfusion policy after severe postpartum haemorrhage: a randomised non-inferiority trial publication-title: BJOG – volume: 4 start-page: 474 year: 2016 end-page: 479 ident: CR57 article-title: Exogenous fibrinogen pertains beneficial effects in managing post-cardiac surgery bleeding: a randomized clinical trial publication-title: J Cardio-Thorac Med – volume: 29 start-page: 261 year: 1999 end-page: 270 ident: CR51 article-title: Acute anemia in high digestive hemorrhage. Margins of secruity for their handling without transfusion of red gobules publication-title: Acta Gastroenterol Latinoam – volume: 64 start-page: 395 year: 2011 end-page: 400 ident: CR8 article-title: GRADE guidelines: 2. Framing the question and deciding on important outcomes publication-title: J Clin Epidemiol – volume: 64 start-page: 1283 year: 2011 end-page: 1293 ident: CR17 article-title: GRADE guidelines 6. Rating the quality of evidence–imprecision publication-title: J Clin Epidemiol – volume: 16 start-page: 916 year: 2017 end-page: 923 ident: CR70 article-title: Rotational thromboelastometry or conventional coagulation tests in liver transplantation: comparing blood loss, transfusions, and cost publication-title: Ann Hepatol – volume: 386 start-page: 137 year: 2015 end-page: 144 ident: CR50 article-title: Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (TRIGGER): a pragmatic, open-label, cluster randomised feasibility trial publication-title: Lancet – volume: 4 year: 2015 ident: CR61 article-title: Randomized, double-blinded, placebo-controlled trial of fibrinogen concentrate supplementation after complex cardiac surgery publication-title: J Am Heart Assoc – volume: 324 start-page: 961 year: 2020 end-page: 974 ident: CR84 article-title: Effect of out-of-hospital tranexamic acid vs placebo on 6-month functional neurologic outcomes in patients with moderate or severe traumatic brain injury publication-title: JAMA – volume: 43 start-page: 26 year: 2012 end-page: 32 ident: CR40 article-title: Early coagulopathy in trauma patients: an on-scene and hospital admission study publication-title: Injury – volume: 8 start-page: 158 year: 1981 end-page: 165 ident: CR86 article-title: Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial publication-title: Neurosurgery – volume: 7 start-page: 119 year: 2017 ident: CR3 article-title: Risks of bleeding and thrombosis in intensive care unit patients with haematological malignancies publication-title: Ann Intensive Care – volume: 32 start-page: 1815 year: 2015 end-page: 1821 ident: CR54 article-title: The effect of platelet and desmopressin administration on early radiographic progression of traumatic intracranial hemorrhage publication-title: J Neurotrauma – volume: 14 start-page: 839 year: 1979 end-page: 844 ident: CR100 article-title: Tranexamic acid in massive haemorrhage from the upper gastrointestinal tract: a double-blind study publication-title: Scand J Gastroenterol – volume: 368 start-page: 11 year: 2013 end-page: 21 ident: CR48 article-title: Transfusion strategies for acute upper gastrointestinal bleeding publication-title: N Engl J Med – volume: 54 start-page: 109 year: 2014 end-page: 118 ident: CR62 article-title: Transfusion and hematologic variables after fibrinogen or platelet transfusion in valve replacement surgery: preliminary data of purified lyophilized human fibrinogen concentrate versus conventional transfusion publication-title: Transfusion – volume: 61 start-page: 99 year: 2018 end-page: 106 ident: CR105 article-title: Tranexamic acid for lower gi hemorrhage: a randomized placebo-controlled clinical trial publication-title: Dis Colon Rectum – volume: 10 start-page: 2504 year: 2005 end-page: 2517 ident: CR55 article-title: Platelet aggregation: involvement of thrombin and fibrin (ogen) publication-title: Front Biosci – volume: 311 start-page: 432 year: 1984 end-page: 437 ident: CR94 article-title: Antifibrinolytic treatment in subarachnoid hemorrhage publication-title: N Engl J Med – year: 2015 ident: CR46 publication-title: Book blood transfusions in obstetrics – volume: 2 start-page: 238 year: 1977 end-page: 242 ident: CR93 article-title: Effect of tranexamic acid on rebleeding after subarachnoid hemorrhage: a double-blind controlled clinical trial publication-title: Ann Neurol – volume: 59 start-page: 1474 year: 2019 end-page: 1478 ident: CR29 article-title: The use of cryopreserved platelets in the treatment of polytraumatic patients and patients with massive bleeding publication-title: Transfusion – volume: 22 start-page: 164 year: 2018 ident: CR37 article-title: Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial publication-title: Crit Care – volume: 394 start-page: 1713 year: 2019 end-page: 1723 ident: CR78 article-title: Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial publication-title: Lancet – volume: 124 start-page: 1777 year: 2017 ident: CR25 article-title: Massive transfusion in cardiac surgery: the impact of blood component ratios on clinical outcomes and survival publication-title: Anesth Analg – year: 2020 ident: CR6 article-title: Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine publication-title: Intensive Care Med doi: 10.1007/s00134-019-05884-8 – volume: 10 start-page: 519 year: 1979 end-page: 522 ident: CR88 article-title: Tranexamic acid in subarachnoid hemorrhage. A double-blind study publication-title: Stroke – volume: 397 start-page: 112 year: 2021 end-page: 118 ident: CR90 article-title: Ultra-early tranexamic acid after subarachnoid haemorrhage (ULTRA): a randomised controlled trial publication-title: Lancet – volume: 2 year: 2017 ident: CR82 article-title: Prehospital tranexamic acid: what is the current evidence? publication-title: Trauma Surg Acute Care Open – volume: 117 start-page: 41 year: 2016 end-page: 51 ident: CR60 article-title: Randomized evaluation of fibrinogen vs placebo in complex cardiovascular surgery (REPLACE): a double-blind phase III study of haemostatic therapy publication-title: Br J Anaesth – volume: 294 start-page: 7 year: 1987 end-page: 10 ident: CR102 article-title: Tranexamic acid as an aid to reducing blood transfusion requirements in gastric and duodenal bleeding publication-title: Br Med J (Clin Res Ed) – volume: 19 start-page: 000 year: 2017 end-page: 000 ident: CR74 article-title: A pilot randomised controlled trial of a totational thromboelastometry-based algorithm to treat bleeding episodes in extracorporeal life support: the TEM protocol in ECLS study (TEMPEST) publication-title: Crit Care Resusc – volume: 389 start-page: 2105 year: 2017 end-page: 2116 ident: CR107 article-title: Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial publication-title: Lancet – volume: 39 start-page: 2135 year: 2013 end-page: 2143 ident: CR1 article-title: Risk factors and impact of major bleeding in critically ill patients receiving heparin thromboprophylaxis publication-title: Intensive Care Med – volume: 64 start-page: 407 year: 2011 end-page: 415 ident: CR14 article-title: GRADE guidelines: 4. Rating the quality of evidence–study limitations (risk of bias) publication-title: J Clin Epidemiol – volume: 117 start-page: 775 year: 2016 end-page: 782 ident: CR39 article-title: Fibrinogen in the initial resuscitation of severe trauma (FiiRST): a randomized feasibility trial publication-title: Br J Anaesth – volume: 216 start-page: 290 year: 2013 end-page: 297 ident: CR41 article-title: Impact of fibrinogen levels on outcomes after acute injury in patients requiring a massive transfusion publication-title: J Am Coll Surg – volume: 54 start-page: 255 year: 2020 end-page: 262 ident: CR68 article-title: Thromboelastography-guided blood product transfusion in cirrhosis patients with variceal bleeding: a randomized controlled trial publication-title: J Clin Gastroenterol – volume: 97 start-page: 771 year: 2002 end-page: 778 ident: CR87 article-title: Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: a prospective randomized study publication-title: J Neurosurg – volume: 313 start-page: 471 year: 2015 end-page: 482 ident: CR20 article-title: Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial publication-title: JAMA – volume: 73 start-page: 783 year: 1986 end-page: 785 ident: CR49 article-title: Effect of early blood transfusion on gastrointestinal hemorrhage publication-title: Br J Surg – year: 2014 ident: CR12 publication-title: Book version 5.4 – volume: 18 start-page: 434 year: 2020 end-page: 445 ident: CR28 article-title: The effect of massive transfusion protocol implementation on the survival of trauma patients: a systematic review and meta-analysis publication-title: Blood Transfus – volume: 19 start-page: 980 year: 2020 end-page: 987 ident: CR95 article-title: Tranexamic acid in patients with intracerebral haemorrhage (STOP-AUST): a multicentre, randomised, placebo-controlled, phase 2 trial publication-title: Lancet Neurol – year: 2017 ident: CR75 article-title: Diagnostic amd therapeutic medical devices for safer blood management in cardiac surgery: systematic reviews, observational studies and randomised controlled trials publication-title: Program Grants Appl Res doi: 10.3310/pgfar05170 – volume: 387 start-page: 2605 year: 2016 end-page: 2613 ident: CR53 article-title: Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial publication-title: Lancet – year: 2020 ident: CR83 article-title: Efficacy and safety of tranexamic acid in acute traumatic brain injury: a systematic review and meta-analysis of randomized-controlled trials publication-title: Intensive Care Med doi: 10.1007/s00134-020-06279-w – volume: 126 start-page: 149 year: 2021 end-page: 156 ident: CR76 article-title: Patient blood management interventions do not lead to important clinical benefits or cost-effectiveness for major surgery: a network meta-analysis publication-title: Br J Anaesth – volume: 71 start-page: 235 year: 2020 end-page: 246 ident: CR67 article-title: Thromboelastography-guided blood component use in patients with cirrhosis with nonvariceal bleeding: a randomized controlled trial publication-title: Hepatology – volume: 20 start-page: 5 year: 2016 ident: CR33 article-title: Safety and efficacy of prothrombin complex concentrate as first-line treatment in bleeding after cardiac surgery publication-title: Crit Care – volume: 120 start-page: 928 year: 2018 end-page: 934 ident: CR34 article-title: Use of prothrombin complex concentrate for management of coagulopathy after cardiac surgery: a propensity score matched comparison to plasma publication-title: Br J Anaesth – volume: 263 start-page: 1051 year: 2016 end-page: 1059 ident: CR71 article-title: Goal-directed hemostatic resuscitation of trauma-induced coagulopathy: a pragmatic randomized clinical trial comparing a viscoelastic assay to conventional coagulation assays publication-title: Ann Surg – volume: 32 start-page: 6 year: 2018 end-page: 15 ident: CR19 article-title: Optimal dose, timing and ratio of blood products in massive transfusion: results from a systematic review publication-title: Transfus Med Rev – volume: 391 start-page: 2107 year: 2018 end-page: 2115 ident: CR97 article-title: Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial publication-title: Lancet – volume: 118 start-page: 823 year: 2017 end-page: 833 ident: CR73 article-title: Routine use of viscoelastic blood tests for diagnosis and treatment of coagulopathic bleeding in cardiac surgery: updated systematic review and meta-analysis publication-title: Br J Anaesth – volume: 337 start-page: a744 year: 2008 ident: CR18 article-title: Use of GRADE grid to reach decisions on clinical practice guidelines when consensus is elusive publication-title: Br Med J – volume: 336 start-page: 924 year: 2008 end-page: 926 ident: CR7 article-title: GRADE: an emerging consensus on rating quality of evidence and strength of recommendations publication-title: BMJ – volume: 152 start-page: 574 year: 2017 end-page: 580 ident: CR23 article-title: Association between ratio of fresh frozen plasma to red blood cells during massive transfusion and survival among patients without traumatic injury publication-title: JAMA Surg – volume: 36 start-page: 34 year: 2018 end-page: 41 ident: CR27 article-title: Retrospective study to investigate fresh frozen plasma and packed cell ratios when administered for women with postpartum hemorrhage, before and after introduction of a massive transfusion protocol publication-title: Int J Obstet Anesth – year: 2019 ident: CR64 article-title: Effect of fibrinogen concentrate vs cryoprecipitate on blood component transfusion after cardiac surgery: the FIBRES randomized clinical trial publication-title: JAMA doi: 10.1001/jama.2019.17312 – volume: 377 start-page: 1096 year: 2011 end-page: 1101 ident: CR81 article-title: The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial publication-title: Lancet – volume: 102 start-page: 1 year: 1990 end-page: 10 ident: CR92 article-title: Benefits and risks of antifibrinolytic therapy in the management of ruptured intracranial aneurysms. A double-blind placebo-controlled study publication-title: Acta Neurochir (Wien) – volume: 15 start-page: 382 year: 2012 end-page: 389 ident: CR31 article-title: Use of prothrombin complex concentrate for excessive bleeding after cardiac surgery publication-title: Interact Cardiovasc Thorac Surg – year: 2011 ident: CR11 article-title: The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses publication-title: The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses – volume: 34 start-page: 119 year: 2020 end-page: 127 ident: CR72 article-title: Viscoelastic blood tests use in adult cardiac surgery: meta-analysis, meta-regression, and trial sequential analysis publication-title: J Cardiothorac Vasc Anesth – volume: 18 start-page: 1 year: 2014 end-page: 8 ident: CR42 article-title: Prevalence, predictors and outcome of hypofibrinogenaemia in trauma: a multicentre observational study publication-title: Crit Care – volume: 121 start-page: 26 year: 2015 end-page: 33 ident: CR35 article-title: An exploratory cohort study comparing prothrombin complex concentrate and fresh frozen plasma for the treatment of coagulopathy after complex cardiac surgery publication-title: Anesth Analg – volume: 1 start-page: 945 year: 1978 end-page: 947 ident: CR89 article-title: Prolonged antifibrinolysis: an effective non-surgical treatment for ruptured intracranial aneurysms? publication-title: Br Med J – volume: 23 start-page: 108 year: 2013 end-page: 113 ident: CR24 article-title: Experience with a massive transfusion protocol in the management of massive haemorrhage publication-title: Transfus Med – volume: 5 start-page: 210 year: 2016 ident: CR9 article-title: Rayyan: a web and mobile app for systematic reviews publication-title: Syst Rev – volume: 376 start-page: 23 year: 2010 end-page: 32 ident: CR77 article-title: Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial publication-title: Lancet – volume: 6 year: 2011 ident: CR79 article-title: Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial publication-title: PLoS ONE – volume: 23 start-page: 1312 year: 2014 end-page: 1318 ident: CR96 article-title: Tranexamic acid for spontaneous intracerebral hemorrhage: a randomized controlled pilot trial (ISRCTN50867461) publication-title: J Stroke Cerebrovasc Dis – volume: 15 start-page: R117 year: 2011 ident: CR108 article-title: High-dose tranexamic acid reduces blood loss in postpartum haemorrhage publication-title: Crit Care – volume: 8 start-page: 76 year: 2017 end-page: 81 ident: CR106 article-title: Role of intra-gastric tranexamic acid in management of acute upper gastrointestinal bleeding publication-title: IIOAB J – volume: 64 start-page: 1294 year: 2011 end-page: 1302 ident: CR15 article-title: GRADE guidelines: 7. Rating the quality of evidence–inconsistency publication-title: J Clin Epidemiol – volume: 74 start-page: 180 year: 2019 end-page: 189 ident: CR58 article-title: Fibrinogen concentrate vs. fresh frozen plasma for the management of coagulopathy during thoraco-abdominal aortic aneurysm surgery: a pilot randomised controlled trial publication-title: Anaesthesia – volume: 11 start-page: 307 year: 2013 ident: 6531_CR80 publication-title: J Thromb Haemost doi: 10.1111/jth.12078 – volume: 137 start-page: 12 year: 2015 ident: 6531_CR52 publication-title: Clin Neurol Neurosurg doi: 10.1016/j.clineuro.2015.06.007 – volume: 368 start-page: 11 year: 2013 ident: 6531_CR48 publication-title: N Engl J Med doi: 10.1056/NEJMoa1211801 – volume: 4 year: 2015 ident: 6531_CR61 publication-title: J Am Heart Assoc doi: 10.1161/JAHA.115.002066 – volume: 15 start-page: 382 year: 2012 ident: 6531_CR31 publication-title: Interact Cardiovasc Thorac Surg doi: 10.1093/icvts/ivs224 – volume: 64 start-page: 395 year: 2011 ident: 6531_CR8 publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2010.09.012 – volume: 1 start-page: 945 year: 1978 ident: 6531_CR89 publication-title: Br Med J doi: 10.1136/bmj.1.6118.945 – volume: 14 start-page: 839 year: 1979 ident: 6531_CR100 publication-title: Scand J Gastroenterol doi: 10.3109/00365527909181413 – volume: 64 start-page: 1283 year: 2011 ident: 6531_CR17 publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2011.01.012 – volume: 376 start-page: 23 year: 2010 ident: 6531_CR77 publication-title: Lancet doi: 10.1016/S0140-6736(10)61479-1 – volume: 117 start-page: 41 year: 2016 ident: 6531_CR60 publication-title: Br J Anaesth doi: 10.1093/bja/aew169 – volume: 317 start-page: 738 year: 2017 ident: 6531_CR56 publication-title: JAMA doi: 10.1001/jama.2016.21037 – volume: 376 start-page: 1893 year: 2017 ident: 6531_CR109 publication-title: N Engl J Med doi: 10.1056/NEJMoa1606424 – volume-title: The Newcastle-Ottawa scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses year: 2011 ident: 6531_CR11 – volume: 60 start-page: 1873 year: 2020 ident: 6531_CR43 publication-title: Transfusion doi: 10.1111/trf.15917 – volume: 120 start-page: 928 year: 2018 ident: 6531_CR34 publication-title: Br J Anaesth doi: 10.1016/j.bja.2018.02.017 – volume: 216 start-page: 290 year: 2013 ident: 6531_CR41 publication-title: J Am Coll Surg doi: 10.1016/j.jamcollsurg.2012.10.017 – volume-title: Book version 5.4 year: 2014 ident: 6531_CR12 – volume: 377 start-page: 1096 year: 2011 ident: 6531_CR81 publication-title: Lancet doi: 10.1016/S0140-6736(11)60317-6 – volume: 10 start-page: 2504 year: 2005 ident: 6531_CR55 publication-title: Front Biosci doi: 10.2741/1715 – volume: 337 start-page: a744 year: 2008 ident: 6531_CR18 publication-title: Br Med J doi: 10.1136/bmj.a744 – volume: 36 start-page: 1947 year: 2018 ident: 6531_CR36 publication-title: Am J Emerg Med doi: 10.1016/j.ajem.2018.02.018 – volume: 1 start-page: 1207 year: 1973 ident: 6531_CR103 publication-title: Lancet doi: 10.1016/S0140-6736(73)90525-4 – volume: 19 start-page: 980 year: 2020 ident: 6531_CR95 publication-title: Lancet Neurol doi: 10.1016/S1474-4422(20)30369-0 – volume-title: Book blood transfusions in obstetrics year: 2015 ident: 6531_CR46 – start-page: CD001245 volume-title: Cochrane database system reviews year: 2000 ident: 6531_CR91 – volume: 324 start-page: 961 year: 2020 ident: 6531_CR84 publication-title: JAMA doi: 10.1001/jama.2020.8958 – volume: 4 start-page: e258 year: 2017 ident: 6531_CR38 publication-title: Lancet Haematol doi: 10.1016/S2352-3026(17)30077-7 – volume: 394 start-page: 1713 year: 2019 ident: 6531_CR78 publication-title: Lancet doi: 10.1016/S0140-6736(19)32233-0 – volume: 34 start-page: 119 year: 2020 ident: 6531_CR72 publication-title: J Cardiothorac Vasc Anesth doi: 10.1053/j.jvca.2019.06.030 – volume: 117 start-page: 775 year: 2016 ident: 6531_CR39 publication-title: Br J Anaesth doi: 10.1093/bja/aew343 – volume: 126 start-page: 149 year: 2021 ident: 6531_CR76 publication-title: Br J Anaesth doi: 10.1016/j.bja.2020.04.087 – volume: 4 start-page: 474 year: 2016 ident: 6531_CR57 publication-title: J Cardio-Thorac Med – year: 2020 ident: 6531_CR83 publication-title: Intensive Care Med doi: 10.1007/s00134-020-06279-w – volume: 23 start-page: 108 year: 2013 ident: 6531_CR24 publication-title: Transfus Med doi: 10.1111/tme.12022 – volume: 391 start-page: 2107 year: 2018 ident: 6531_CR97 publication-title: Lancet doi: 10.1016/S0140-6736(18)31033-X – volume: 45 start-page: 1311 year: 2017 ident: 6531_CR22 publication-title: Crit Care Med doi: 10.1097/CCM.0000000000002498 – start-page: CD009052 volume-title: Cochrane database of systematic reviews year: 2011 ident: 6531_CR69 – volume: 15 start-page: R117 year: 2011 ident: 6531_CR108 publication-title: Crit Care doi: 10.1186/cc10143 – volume: 22 start-page: 164 year: 2018 ident: 6531_CR37 publication-title: Crit Care doi: 10.1186/s13054-018-2086-x – 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6531_CR27 publication-title: Int J Obstet Anesth doi: 10.1016/j.ijoa.2018.08.001 – volume: 118 start-page: 823 year: 2017 ident: 6531_CR73 publication-title: Br J Anaesth doi: 10.1093/bja/aex100 – year: 2019 ident: 6531_CR64 publication-title: JAMA doi: 10.1001/jama.2019.17312 – start-page: e106 volume-title: Prevention and management of postpartum haemorrhage: green-top guideline no. 52 year: 2017 ident: 6531_CR47 – volume: 43 start-page: 26 year: 2012 ident: 6531_CR40 publication-title: Injury doi: 10.1016/j.injury.2010.11.003 – volume: 5 start-page: 210 year: 2016 ident: 6531_CR9 publication-title: Syst Rev doi: 10.1186/s13643-016-0384-4 – volume: 263 start-page: 1051 year: 2016 ident: 6531_CR71 publication-title: Ann Surg doi: 10.1097/SLA.0000000000001608 – volume: 64 start-page: 1294 year: 2011 ident: 6531_CR15 publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2011.03.017 – volume: 124 start-page: 1777 year: 2017 ident: 6531_CR25 publication-title: Anesth Analg doi: 10.1213/ANE.0000000000001926 – volume: 18 start-page: 434 year: 2020 ident: 6531_CR28 publication-title: Blood Transfus – volume: 97 start-page: 771 year: 2002 ident: 6531_CR87 publication-title: J Neurosurg doi: 10.3171/jns.2002.97.4.0771 – volume: 54 start-page: 109 year: 2014 ident: 6531_CR62 publication-title: Transfusion doi: 10.1111/trf.12248 – volume: 121 start-page: 1005 year: 2014 ident: 6531_CR45 publication-title: BJOG doi: 10.1111/1471-0528.12531 – volume: 39 start-page: 2135 year: 2013 ident: 6531_CR1 publication-title: Intensive Care Med doi: 10.1007/s00134-013-3044-3 – volume: 2 year: 2017 ident: 6531_CR82 publication-title: Trauma Surg Acute Care Open doi: 10.1136/tsaco-2016-000056 – volume-title: Cochrane handbook for systematic reviews of interventions year: 2019 ident: 6531_CR10 doi: 10.1002/9781119536604 – volume: 61 start-page: 99 year: 2018 ident: 6531_CR105 publication-title: Dis Colon Rectum doi: 10.1097/DCR.0000000000000943 – volume: 313 start-page: 471 year: 2015 ident: 6531_CR20 publication-title: JAMA doi: 10.1001/jama.2015.12 – volume: 6 year: 2011 ident: 6531_CR79 publication-title: PLoS ONE doi: 10.1371/journal.pone.0018987 – volume: 152 start-page: 574 year: 2017 ident: 6531_CR23 publication-title: JAMA Surg doi: 10.1001/jamasurg.2017.0098 – volume: 8 start-page: 76 year: 2017 ident: 6531_CR106 publication-title: IIOAB J – volume: 32 start-page: 6 year: 2018 ident: 6531_CR19 publication-title: Transfus Med Rev doi: 10.1016/j.tmrv.2017.06.003 – volume: 34 start-page: 861 year: 2017 ident: 6531_CR26 publication-title: Am J Perinatol doi: 10.1055/s-0037-1599103 – year: 2020 ident: 6531_CR6 publication-title: Intensive Care Med doi: 10.1007/s00134-019-05884-8 – volume: 18 start-page: 1 year: 2014 ident: 6531_CR42 publication-title: Crit Care doi: 10.1186/cc13798 – volume: 32 start-page: 1815 year: 2015 ident: 6531_CR54 publication-title: J Neurotrauma doi: 10.1089/neu.2014.3728 – volume: 6 start-page: 46 year: 2018 ident: 6531_CR101 publication-title: United Eur Gastroenterol J doi: 10.1177/2050640617714940 – volume: 23 start-page: 309 year: 2019 ident: 6531_CR5 publication-title: Crit Care doi: 10.1186/s13054-019-2591-6 – volume: 64 start-page: 407 year: 2011 ident: 6531_CR14 publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2010.07.017 – volume: 311 start-page: 432 year: 1984 ident: 6531_CR94 publication-title: N Engl J Med doi: 10.1056/NEJM198408163110703 – volume: 3 start-page: 502 year: 1978 ident: 6531_CR85 publication-title: Ann Neurol doi: 10.1002/ana.410030607 – year: 2017 ident: 6531_CR75 publication-title: Program Grants Appl Res doi: 10.3310/pgfar05170 – volume: 29 start-page: 683 year: 2018 ident: 6531_CR2 publication-title: Blood Coagul Fibrinolysis doi: 10.1097/MBC.0000000000000777 – volume: 71 start-page: 235 year: 2020 ident: 6531_CR67 publication-title: Hepatology doi: 10.1002/hep.30794 – volume: 85 start-page: 173 year: 1980 ident: 6531_CR104 publication-title: Upsala J Med Sci doi: 10.3109/03009738009179185 – volume: 133 start-page: 2639 year: 2019 ident: 6531_CR44 publication-title: Blood doi: 10.1182/blood-2018-10-877530 – volume: 7 start-page: 119 year: 2017 ident: 6531_CR3 publication-title: Ann Intensive Care doi: 10.1186/s13613-017-0341-y – volume: 59 start-page: 1474 year: 2019 ident: 6531_CR29 publication-title: Transfusion doi: 10.1111/trf.15177 – volume: 103 start-page: 25 year: 2012 ident: 6531_CR63 publication-title: Vox Sang doi: 10.1111/j.1423-0410.2011.01575.x – volume: 29 start-page: 261 year: 1999 ident: 6531_CR51 publication-title: Acta Gastroenterol Latinoam – volume: 397 start-page: 112 year: 2021 ident: 6531_CR90 publication-title: Lancet doi: 10.1016/S0140-6736(20)32518-6 – volume: 28 start-page: 1881 year: 2019 ident: 6531_CR32 publication-title: Heart Lung Circ doi: 10.1016/j.hlc.2018.10.025 – volume: 8 start-page: 158 year: 1981 ident: 6531_CR86 publication-title: Neurosurgery doi: 10.1227/00006123-198102000-00004 – volume: 10 start-page: 519 year: 1979 ident: 6531_CR88 publication-title: Stroke doi: 10.1161/01.STR.10.5.519 – volume: 294 start-page: 7 year: 1987 ident: 6531_CR102 publication-title: Br Med J (Clin Res Ed) doi: 10.1136/bmj.294.6563.7 – volume: 111 start-page: i71 issue: Suppl 1 year: 2013 ident: 6531_CR4 publication-title: Br J Anaesth doi: 10.1093/bja/aet376 – volume: 121 start-page: 26 year: 2015 ident: 6531_CR35 publication-title: Anesth Analg doi: 10.1213/ANE.0000000000000689 – volume: 49 start-page: 53 year: 2018 ident: 6531_CR66 publication-title: Shock doi: 10.1097/SHK.0000000000000918 – volume: 308 start-page: 1571 year: 1983 ident: 6531_CR99 publication-title: N Engl J Med doi: 10.1056/NEJM198306303082606 – volume: 133 start-page: 1173 year: 2020 ident: 6531_CR30 publication-title: Anesthesiology doi: 10.1097/ALN.0000000000003550 – volume: 395 start-page: 1927 year: 2020 ident: 6531_CR98 publication-title: Lancet doi: 10.1016/S0140-6736(20)30848-5 – volume: 74 start-page: 180 year: 2019 ident: 6531_CR58 publication-title: Anaesthesia doi: 10.1111/anae.14495 – volume: 16 start-page: 916 year: 2017 ident: 6531_CR70 publication-title: Ann Hepatol doi: 10.5604/01.3001.0010.5283 – volume: 185 start-page: E583 year: 2013 ident: 6531_CR21 publication-title: CMAJ doi: 10.1503/cmaj.121986 – volume: 20 start-page: 5 year: 2016 ident: 6531_CR33 publication-title: Crit Care doi: 10.1186/s13054-015-1172-6 – volume: 389 start-page: 2105 year: 2017 ident: 6531_CR107 publication-title: Lancet doi: 10.1016/S0140-6736(17)30638-4 – volume: 21 start-page: 160 year: 2017 ident: 6531_CR65 publication-title: Crit Care doi: 10.1186/s13054-017-1745-7 – volume: 19 start-page: 000 year: 2017 ident: 6531_CR74 publication-title: Crit Care Resusc – volume: 73 start-page: 783 year: 1986 ident: 6531_CR49 publication-title: Br J Surg doi: 10.1002/bjs.1800731007 – volume: 64 start-page: 1303 year: 2011 ident: 6531_CR16 publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2011.04.014 – volume: 54 start-page: 255 year: 2020 ident: 6531_CR68 publication-title: J Clin Gastroenterol doi: 10.1097/MCG.0000000000001214 |
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To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.
Methods... To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. A taskforce... Purpose To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. Methods... To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults. A taskforce... PurposeTo develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.MethodsA... To develop evidence-based clinical practice recommendations regarding transfusion practices and transfusion in bleeding critically ill adults.PURPOSETo develop... |
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| Title | Transfusion strategies in bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine |
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