Vasoactive intestinal peptide promotes secretory differentiation and mitigates radiation-induced intestinal injury

Background Vasoactive intestinal peptide (VIP) is a neuronal peptide with prominent distribution along the enteric nervous system. While effects of VIP on intestinal motility, mucosal vasodilation, secretion, and mucosal immune cell function are well-studied, the direct impact of VIP on intestinal e...

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Bibliographic Details
Published in:	Stem cell research & therapy Vol. 15; no. 1; pp. 348 - 14
Main Authors:	Agibalova, Tatiana, Hempel, Anneke, Maurer, H. Carlo, Ragab, Mohab, Ermolova, Anastasia, Wieland, Jessica, Waldherr Ávila de Melo, Caroline, Heindl, Fabian, Giller, Maximilian, Fischer, Julius Clemens, Tschurtschenthaler, Markus, Kohnke-Ertel, Birgit, Öllinger, Rupert, Steiger, Katja, Demir, Ihsan Ekin, Saur, Dieter, Quante, Michael, Schmid, Roland M., Middelhoff, Moritz
Format:	Journal Article
Language:	English
Published:	London BioMed Central 08.10.2024 BioMed Central Ltd BMC
Subjects:	Animals Biomedical and Life Sciences Biomedical Engineering and Bioengineering Blood vessels Cell Biology Cell Differentiation Dilatation Ethylenediaminetetraacetic acid Female Flumazenil Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Intestinal Mucosa - radiation effects Intestinal progenitor cells Irradiation Life Sciences Male Mice Mice, Inbred C57BL Organoids - metabolism Radiation Radiation Injuries - metabolism Radiation Injuries - pathology Regeneration Regenerative Medicine/Tissue Engineering Scientific equipment and supplies industry Stem Cells Stem Cells - drug effects Stem Cells - metabolism Stem Cells - radiation effects Vasoactive Intestinal Peptide - metabolism Vasoactive Intestinal Peptide - pharmacology Vasoactive intestinal peptides VIP United States Irradiation Regeneration Intestinal progenitor cells VIP
ISSN:	1757-6512, 1757-6512
Online Access:	Get full text
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