Identification of hub gene for the pathogenic mechanism and diagnosis of MASLD by enhanced bioinformatics analysis and machine learning

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous disease caused by multiple etiologies. It is characterized by excessive fat accumulation in the liver. Without intervention, MASLD can progress from steatosis to metabolic dysfunction-associated steatohepatitis (MASH...

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Vydáno v:	PloS one Ročník 20; číslo 5; s. e0324972
Hlavní autoři:	Lu, Hong, Mao, Ziyong, Zheng, Mengyao, Zhang, Min, Huang, Heqing, Chen, Yiling, Lv, Long, Chen, Zutao
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 28.05.2025 Public Library of Science (PLoS)
Témata:	Bioinformatics Biology and Life Sciences Biopsy Cirrhosis Computational biology Computational Biology - methods Diagnosis Fatty liver Fatty Liver - diagnosis Fatty Liver - genetics Fatty Liver - pathology Fibrosis Gene expression Gene Expression Profiling Genes Genetic aspects Hepatocellular carcinoma Humans Inflammation Lipid metabolism Lipid Metabolism - genetics Lipids Liver Liver Cirrhosis - diagnosis Liver Cirrhosis - genetics Liver diseases Machine Learning Medical genetics Medicine and Health Sciences Metabolism Pathogenesis Proteins Ribonucleic acid RNA Software Steatosis Variables China
ISSN:	1932-6203, 1932-6203
On-line přístup:	Získat plný text
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