Predictability of clinical outcomes after external beam radiotherapy for hepatocellular carcinoma according to tumor marker dynamics

Signal changes after high dose irradiation on MRI make it difficult to assess the therapeutic response of hepatocellular carcinoma (HCC). To overcome the limitation of imaging work-up, our study predicted clinical outcomes through tumor marker dynamics in HCC after external beam radiotherapy (EBRT)....

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Bibliographic Details
Published in:	PloS one Vol. 20; no. 5; p. e0323450
Main Authors:	Park, Sunmin, Rim, Chai Hong, Jung, Young Kul, Yim, Hyung Joon, Chung, Hwan Hoon, Yoon, Won Sup
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 20.05.2025 Public Library of Science (PLoS)
Subjects:	Adult Aged alpha-Fetoproteins - metabolism Biology and Life Sciences Biomarkers Biomarkers, Tumor - blood Biomarkers, Tumor - metabolism Blood clots Carcinoma, Hepatocellular - blood Carcinoma, Hepatocellular - metabolism Carcinoma, Hepatocellular - mortality Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - radiotherapy Care and treatment Chemotherapy Clinical outcomes Female Hepatitis B Hepatocellular carcinoma Hepatoma Humans Irradiation Liver cancer Liver Neoplasms - blood Liver Neoplasms - metabolism Liver Neoplasms - mortality Liver Neoplasms - pathology Liver Neoplasms - radiotherapy Magnetic resonance imaging Male Measurement Medical prognosis Medicine and Health Sciences Metastasis Middle Aged Multivariate analysis Patient outcomes Patients Physical Sciences Portal vein Prognosis Protein Precursors Prothrombin - metabolism Radiation dosage Radiation therapy Radiotherapy Remission Research and Analysis Methods Retrospective Studies Sensitivity Simulation Thrombosis Treatment Outcome Tumor markers Tumors Slovenia United States > US
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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