Three hospitalized non-critical COVID-19 subphenotypes and change in intubation or death over time: A latent class analysis with external and longitudinal validation

There are two subphenotypes of COVID-19 acute respiratory distress syndrome with differential responses to corticosteroids, but whether similar subphenotypes of hospitalized non-critical COVID-19 patients exist remains unknown. To identify and validate non-critical COVID-19 subphenotypes at hospital...

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Bibliographic Details
Published in:	PloS one Vol. 20; no. 3; p. e0316434
Main Authors:	Stringer, William S., Labar, Amy S., Geleris, Joshua D., Sholle, Evan V., Berlin, David A., McGroder, Claire M., Cummings, Matthew J., O’Donnell, Max R., Yi, Haoyang, Yang, Xuehan, Wei, Ying, Schenck, Edward J., Baldwin, Matthew R.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 19.03.2025 Public Library of Science (PLoS)
Subjects:	Acute respiratory distress syndrome Adult Adults Aged Analysis Biology and Life Sciences Biomarkers C-reactive protein Care and treatment Clinical trials Coronaviruses Corticoids Corticosteroids COVID-19 COVID-19 - mortality COVID-19 - pathology COVID-19 - therapy COVID-19 - virology Death Emergency medical care Entropy Female Fibrinolysis Forecasts and trends Health aspects Health care facilities Health services Heterogeneity Hospitalization Hospitals Humans Inflammation Intubation Latent Class Analysis Learning algorithms Longitudinal Studies Machine Learning Male Medical research Medicine and Health Sciences Medicine, Experimental Middle Aged Mortality Patients Phenotype Physical Sciences Probability Research and Analysis Methods Respiratory distress syndrome Retrospective Studies Risk factors Rivaroxaban SARS-CoV-2 - isolation & purification Severe acute respiratory syndrome Severe acute respiratory syndrome coronavirus 2 United States Variables Vital signs United States United Kingdom
ISSN:	1932-6203, 1932-6203
Online Access:	Get full text
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