Discovery and validation of cell cycle arrest biomarkers in human acute kidney injury

Introduction Acute kidney injury (AKI) can evolve quickly and clinical measures of function often fail to detect AKI at a time when interventions are likely to provide benefit. Identifying early markers of kidney damage has been difficult due to the complex nature of human AKI, in which multiple eti...

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Bibliographic Details
Published in:	Critical care (London, England) Vol. 17; no. 1; p. R25
Main Authors:	Kashani, Kianoush, Al-Khafaji, Ali, Ardiles, Thomas, Artigas, Antonio, Bagshaw, Sean M, Bell, Max, Bihorac, Azra, Birkhahn, Robert, Cely, Cynthia M, Chawla, Lakhmir S, Davison, Danielle L, Feldkamp, Thorsten, Forni, Lui G, Gong, Michelle Ng, Gunnerson, Kyle J, Haase, Michael, Hackett, James, Honore, Patrick M, Hoste, Eric AJ, Joannes-Boyau, Olivier, Joannidis, Michael, Kim, Patrick, Koyner, Jay L, Laskowitz, Daniel T, Lissauer, Matthew E, Marx, Gernot, McCullough, Peter A, Mullaney, Scott, Ostermann, Marlies, Rimmelé, Thomas, Shapiro, Nathan I, Shaw, Andrew D, Shi, Jing, Sprague, Amy M, Vincent, Jean-Louis, Vinsonneau, Christophe, Wagner, Ludwig, Walker, Michael G, Wilkerson, R Gentry, Zacharowski, Kai, Kellum, John A
Format:	Journal Article
Language:	English
Published:	London BioMed Central 06.02.2013 BioMed Central Ltd
Subjects:	Acute Kidney Injury - diagnosis Acute Kidney Injury - urine Acute renal failure Aged Biological markers Biomarkers - urine Cell cycle Cell Cycle Checkpoints - physiology Cohort Studies Comparative analysis Critical Care Medicine Emergency Medicine Female Humans Insulin-Like Growth Factor Binding Proteins - urine Intensive Male Medical research Medicine Medicine & Public Health Medicine, Experimental Middle Aged Pharmaceutical industry Physiological aspects Protein binding Tissue Inhibitor of Metalloproteinase-2 - urine United States Integrate Discrimination Improvement Acute Kidney Injury Renal Replacement Therapy Persistent Renal Dysfunction Plasma NGAL
ISSN:	1364-8535, 1466-609X, 1364-8535, 1466-609X
Online Access:	Get full text
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