GALNT6 promotes bladder cancer malignancy and immune escape by epithelial-mesenchymal transition and CD8+ T cells

Bladder cancer (BC) ranks as the sixth cancer in males and the ninth most common cancer worldwide. Conventional treatment modalities, including surgery, radiation, chemotherapy, and immunotherapy, have limited efficacy in certain advanced instances. The involvement of GALNT6-mediated aberrant O-glyc...

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Veröffentlicht in:	Cancer cell international Jg. 24; H. 1; S. 308 - 18
Hauptverfasser:	Sun, Xiaoxin, Wu, Haotian, Tang, Ling, Al-Danakh, Abdullah, Jian, Yuli, Gong, Li, Li, Congchen, Yu, Xiao, Zeng, Guang, Chen, Qiwei, Yang, Deyong, Wang, Shujing
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 08.09.2024 Springer Nature B.V BMC
Schlagworte:	Antigens Bioinformatics Biomarkers Biomedical and Life Sciences Biomedicine Bladder cancer Cancer Research CD8 antigen Cell Biology Cell culture Chemotherapy Epithelial-mesenchymal transition GALNT6 Gene expression Genomes Glycosylation Immune evasion Immunotherapy Liver cancer Lymphocytes T Malignancy Medical prognosis Metastases Molecular modelling O-glycosylation Oncology Online data bases Polypeptides Prostate Tumor cells Tumor immune escape Tumor microenvironment Tumors GALNT6 Epithelial-mesenchymal transition O-glycosylation Tumor immune escape Bladder cancer
ISSN:	1475-2867, 1475-2867
Online-Zugang:	Volltext
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