Placental transcriptome analysis of hypertensive pregnancies identifies distinct gene expression profiles of preeclampsia superimposed on chronic hypertension

Background The pathogenesis of preeclampsia superimposed on chronic hypertension (SI) is poorly understood relative to preeclampsia (PreE) occurring in pregnant people without chronic hypertension. Placental transcriptomes in pregnancies complicated by PreE and SI have not been previously compared....

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Bibliographic Details
Published in:	BMC medical genomics Vol. 16; no. 1; pp. 91 - 11
Main Authors:	Hesson, Ashley M., Langen, Elizabeth S., Plazyo, Olesya, Gudjonsson, Johann E., Ganesh, Santhi K.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 02.05.2023 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Biomarkers Biomedical and Life Sciences Biomedicine Child Correlation analysis Development and progression Disease Female Gene Expression Gene Expression Profiling Genetic aspects Genomics Gestational age Human Genetics Humans Hypertension Hypertension - complications Hypertension - genetics Hypertension in pregnancy Infant, Newborn Inhibin Intensive care Microarrays Ontology Paraffin Pediatrics Placenta Pre-eclampsia Pre-Eclampsia - etiology Preeclampsia Pregnancy Pregnancy complications Principal components analysis Quality control Risk factors RNASeq Transcriptome Transcriptomes United States United States > US Hypertension Biomarkers RNASeq Preeclampsia Inhibin
ISSN:	1755-8794, 1755-8794
Online Access:	Get full text
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