Progress Toward Regional Measles Elimination — Worldwide, 2000–2020

In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan,* with the objective of eliminating measles in five of the six World Health Organization (WHO) regions by 2020 (1). The Immunization Agenda 2021-2030 (IA2030) uses measles incidence as an indicator of the strength of immuniza...

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Vydáno v:MMWR. Morbidity and mortality weekly report Ročník 70; číslo 45; s. 1563 - 1569
Hlavní autoři: Dixon, Meredith G., Ferrari, Matt, Antoni, Sebastien, Li, Xi, Portnoy, Allison, Lambert, Brian, Hauryski, Sarah, Hatcher, Cynthia, Nedelec, Yoann, Patel, Minal, Alexander, James P., Steulet, Claudia, Gacic-Dobo, Marta, Rota, Paul A., Mulders, Mick N., Bose, Anindya S., Rosewell, Alexander, Kretsinger, Katrina, Crowcroft, Natasha S.
Médium: Journal Article Newsletter
Jazyk:angličtina
Vydáno: United States Centers for Disease Control & Prevention (CDC) 12.11.2021
U.S. Government Printing Office
U.S. Center for Disease Control
Centers for Disease Control and Prevention
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ISSN:0149-2195, 1545-861X, 1545-861X
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Abstract In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan,* with the objective of eliminating measles in five of the six World Health Organization (WHO) regions by 2020 (1). The Immunization Agenda 2021-2030 (IA2030) uses measles incidence as an indicator of the strength of immunization systems. The Measles-Rubella Strategic Framework 2021-2030 and the Measles Outbreaks Strategic Response Plan 2021-2023** are aligned with the IA2030 and highlight robust measles surveillance systems to document immunity gaps, identify root causes of undervaccination, and develop locally tailored solutions to ensure administration of 2 doses of measles-containing vaccine (MCV) to all children. This report describes progress toward World Health Assembly milestones and measles elimination objectives during 2000-2020 and updates a previous report (2). During 2000-2010, estimated MCV first dose (MCV1) coverage increased globally from 72% to 84%, peaked at 86% in 2019, but declined to 84% in 2020 during the COVID-19 pandemic. All countries conducted measles surveillance, although fewer than one third achieved the sensitivity indicator target of ≥2 discarded cases per 100,000 population in 2020. Annual reported measles incidence decreased 88% during 2000-2016, from 145 to 18 cases per 1 million population, rebounded to 120 in 2019, before falling to 22 in 2020. During 2000-2020, the annual number of estimated measles deaths decreased 94%, from 1,072,800 to 60,700, averting an estimated 31.7 million measles deaths. To achieve regional measles elimination targets, enhanced efforts are needed to reach all children with 2 MCV doses, implement robust surveillance, and identify and close immunity gaps.
AbstractList In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan,* with the objective of eliminating measles† in five of the six World Health Organization (WHO) regions by 2020 (1). The Immunization Agenda 2021-2030 (IA2030)§ uses measles incidence as an indicator of the strength of immunization systems. The Measles-Rubella Strategic Framework 2021-2030¶ and the Measles Outbreaks Strategic Response Plan 2021-2023** are aligned with the IA2030 and highlight robust measles surveillance systems to document immunity gaps, identify root causes of undervaccination, and develop locally tailored solutions to ensure administration of 2 doses of measles-containing vaccine (MCV) to all children. This report describes progress toward World Health Assembly milestones and measles elimination objectives during 2000-2020 and updates a previous report (2). During 2000-2010, estimated MCV first dose (MCV1) coverage increased globally from 72% to 84%, peaked at 86% in 2019, but declined to 84% in 2020 during the COVID-19 pandemic. All countries conducted measles surveillance, although fewer than one third achieved the sensitivity indicator target of ≥2 discarded†† cases per 100,000 population in 2020. Annual reported measles incidence decreased 88% during 2000-2016, from 145 to 18 cases per 1 million population, rebounded to 120 in 2019, before falling to 22 in 2020. During 2000-2020, the annual number of estimated measles deaths decreased 94%, from 1,072,800 to 60,700, averting an estimated 31.7 million measles deaths. To achieve regional measles elimination targets, enhanced efforts are needed to reach all children with 2 MCV doses, implement robust surveillance, and identify and close immunity gaps.In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan,* with the objective of eliminating measles† in five of the six World Health Organization (WHO) regions by 2020 (1). The Immunization Agenda 2021-2030 (IA2030)§ uses measles incidence as an indicator of the strength of immunization systems. The Measles-Rubella Strategic Framework 2021-2030¶ and the Measles Outbreaks Strategic Response Plan 2021-2023** are aligned with the IA2030 and highlight robust measles surveillance systems to document immunity gaps, identify root causes of undervaccination, and develop locally tailored solutions to ensure administration of 2 doses of measles-containing vaccine (MCV) to all children. This report describes progress toward World Health Assembly milestones and measles elimination objectives during 2000-2020 and updates a previous report (2). During 2000-2010, estimated MCV first dose (MCV1) coverage increased globally from 72% to 84%, peaked at 86% in 2019, but declined to 84% in 2020 during the COVID-19 pandemic. All countries conducted measles surveillance, although fewer than one third achieved the sensitivity indicator target of ≥2 discarded†† cases per 100,000 population in 2020. Annual reported measles incidence decreased 88% during 2000-2016, from 145 to 18 cases per 1 million population, rebounded to 120 in 2019, before falling to 22 in 2020. During 2000-2020, the annual number of estimated measles deaths decreased 94%, from 1,072,800 to 60,700, averting an estimated 31.7 million measles deaths. To achieve regional measles elimination targets, enhanced efforts are needed to reach all children with 2 MCV doses, implement robust surveillance, and identify and close immunity gaps.
In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan,* with the objective of eliminating measles in five of the six World Health Organization (WHO) regions by 2020 (1). The Immunization Agenda 2021-2030 (IA2030) uses measles incidence as an indicator of the strength of immunization systems. The Measles-Rubella Strategic Framework 2021-2030 and the Measles Outbreaks Strategic Response Plan 2021-2023** are aligned with the IA2030 and highlight robust measles surveillance systems to document immunity gaps, identify root causes of undervaccination, and develop locally tailored solutions to ensure administration of 2 doses of measles-containing vaccine (MCV) to all children. This report describes progress toward World Health Assembly milestones and measles elimination objectives during 2000-2020 and updates a previous report (2). During 2000-2010, estimated MCV first dose (MCV1) coverage increased globally from 72% to 84%, peaked at 86% in 2019, but declined to 84% in 2020 during the COVID-19 pandemic. All countries conducted measles surveillance, although fewer than one third achieved the sensitivity indicator target of ≥2 discarded cases per 100,000 population in 2020. Annual reported measles incidence decreased 88% during 2000-2016, from 145 to 18 cases per 1 million population, rebounded to 120 in 2019, before falling to 22 in 2020. During 2000-2020, the annual number of estimated measles deaths decreased 94%, from 1,072,800 to 60,700, averting an estimated 31.7 million measles deaths. To achieve regional measles elimination targets, enhanced efforts are needed to reach all children with 2 MCV doses, implement robust surveillance, and identify and close immunity gaps.
What is already known about this topic? All six World Health Organization (WHO) regions remain committed to measles elimination. What is added by this report? Annual reported measles incidence decreased globally during 2000–2016, increased in all regions during 2017–2019, then decreased in 2020. Measles surveillance, already suboptimal, worsened in 2020. Since 2000, estimated measles deaths decreased 94%. Measles vaccination has prevented an estimated 31.7 million deaths worldwide. No WHO region has achieved and maintained measles elimination. What are the implications for public health practice? To achieve regional measles elimination targets, enhanced efforts are needed to reach all children with 2 doses of measles-containing vaccine, implement robust surveillance, and identify and close immunity gaps.
Audience Professional
Author Portnoy, Allison
Gacic-Dobo, Marta
Dixon, Meredith G.
Li, Xi
Mulders, Mick N.
Antoni, Sebastien
Alexander, James P.
Rota, Paul A.
Steulet, Claudia
Patel, Minal
Hatcher, Cynthia
Bose, Anindya S.
Kretsinger, Katrina
Ferrari, Matt
Lambert, Brian
Hauryski, Sarah
Rosewell, Alexander
Nedelec, Yoann
Crowcroft, Natasha S.
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/34758014$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1002/sim.8290
10.1093/infdis/jir100
10.1016/S2214-109X(18)30537-0
10.15585/mmwr.mm6945a6
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Copyright COPYRIGHT 2021 U.S. Government Printing Office
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Issue 45
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License All material in the MMWR Series is in the public domain and may be used and reprinted without permission; citation as to source, however, is appreciated.
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PMID 34758014
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PublicationDate 2021-11-12
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PublicationTitle MMWR. Morbidity and mortality weekly report
PublicationTitleAlternate MMWR Morb Mortal Wkly Rep
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References Patel (key-10.15585/mmwr.mm7045a1-202111100620-R2) 2020; 69
key-10.15585/mmwr.mm7045a1-202111100620-R4
Eilertson (key-10.15585/mmwr.mm7045a1-202111100620-R3) 2019; 38
World Health Organization (key-10.15585/mmwr.mm7045a1-202111100620-R6) 2011; 204
World Health Organization (key-10.15585/mmwr.mm7045a1-202111100620-R7) 2017; 92
key-10.15585/mmwr.mm7045a1-202111100620-R1
Portnoy (key-10.15585/mmwr.mm7045a1-202111100620-R5) 2019; 7
References_xml – volume: 38
  start-page: 4146
  year: 2019
  ident: key-10.15585/mmwr.mm7045a1-202111100620-R3
  article-title: Estimation and prediction for a mechanistic model of measles transmission using particle filtering and maximum likelihood estimation.
  publication-title: Stat Med
  doi: 10.1002/sim.8290
– volume: 204
  start-page: S4
  year: 2011
  ident: key-10.15585/mmwr.mm7045a1-202111100620-R6
  article-title: Proceedings of the Global Technical Consultation to assess the feasibility of measles eradication, 28-30 July 2010.
  publication-title: J Infect Dis
  doi: 10.1093/infdis/jir100
– volume: 7
  start-page: e472
  year: 2019
  ident: key-10.15585/mmwr.mm7045a1-202111100620-R5
  article-title: Estimates of case-fatality ratios of measles in low-income and middle-income countries: a systematic review and modelling analysis.
  publication-title: Lancet Glob Health
  doi: 10.1016/S2214-109X(18)30537-0
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– volume: 69
  start-page: 1700
  year: 2020
  ident: key-10.15585/mmwr.mm7045a1-202111100620-R2
  article-title: Progress toward regional measles elimination—worldwide, 2000–2019.
  publication-title: MMWR Morb Mortal Wkly Rep
  doi: 10.15585/mmwr.mm6945a6
– volume: 92
  start-page: 205
  year: 2017
  ident: key-10.15585/mmwr.mm7045a1-202111100620-R7
  article-title: Measles vaccines: WHO position paper—April 2017.
  publication-title: Wkly Epidemiol Rec
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Snippet In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan,* with the objective of eliminating measles in five of the six World Health...
In 2012, the World Health Assembly endorsed the Global Vaccine Action Plan,* with the objective of eliminating measles† in five of the six World Health...
What is already known about this topic? All six World Health Organization (WHO) regions remain committed to measles elimination. What is added by this report?...
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SubjectTerms Child
Coronaviruses
COVID-19 vaccines
Deaths
Disease Eradication
Disease transmission
Dosage
Elimination
Epidemics
Estimates
Fatalities
Full Report
Global Health - statistics & numerical data
Humans
Immunity
Immunization
Immunization Programs
Incidence
Infant
Measles
Measles - epidemiology
Measles - prevention & control
Measles Vaccine - administration & dosage
Medical laboratories
Mortality
Pandemics
Public health
Regions
Rubella
Surveillance
Vaccination
Vaccines
World Health Organization
Title Progress Toward Regional Measles Elimination — Worldwide, 2000–2020
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