Systematic evaluation of DNA methylation age estimation with common preprocessing methods and the Infinium MethylationEPIC BeadChip array

Background The capacity of technologies measuring DNA methylation (DNAm) is rapidly evolving, as are the options for applicable bioinformatics methods. The most commonly used DNAm microarray, the Illumina Infinium HumanMethylation450 (450K array), has recently been replaced by the Illumina Infinium...

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Bibliographic Details
Published in:	Clinical epigenetics Vol. 10; no. 1; pp. 123 - 9
Main Authors:	McEwen, Lisa M, Jones, Meaghan J, Lin, David Tse Shen, Edgar, Rachel D, Husquin, Lucas T, MacIsaac, Julia L, Ramadori, Katia E, Morin, Alexander M, Rider, Christopher F, Carlsten, Chris, Quintana-Murci, Lluís, Horvath, Steve, Kobor, Michael S
Format:	Journal Article
Language:	English
Published:	London BioMed Central 16.10.2018 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	450K Adult Age Age (Biology) Age determination Aging Aging - genetics Alveoli Analysis Biochemistry, Molecular Biology Bioinformatics Biomedical and Life Sciences Biomedicine Bronchoalveolar Lavage Fluid Bronchoalveolar Lavage Fluid - chemistry Bronchus Cardiovascular disease CpG Islands Data processing Deoxyribonucleic acid DNA DNA Methylation DNA methylation age DNA microarrays DNA probes EPIC Epigenesis, Genetic Epigenetic age Epigenetic clock Epigenetics Epigenomics Female Gene Function Genes Genetics Genomes Genomics Human Genetics Humans Leukocytes (mononuclear) Leukocytes, Mononuclear - chemistry Life Sciences Male Methods Methylation Middle Aged Monocytes Oligonucleotide Array Sequence Analysis Oligonucleotide Array Sequence Analysis - instrumentation Oligonucleotide Array Sequence Analysis - methods Peripheral blood mononuclear cells Short Report Young Adult Human Epigenetic clock 450K Preprocessing DNA methylation age EPIC DNA methylation Microarray Epigenetic age
ISSN:	1868-7075, 1868-7083, 1868-7083, 1868-7075
Online Access:	Get full text
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