Response of the medial temporal lobe network in amnestic mild cognitive impairment to therapeutic intervention assessed by fMRI and memory task performance

Studies of individuals with amnestic mild cognitive impairment (aMCI) have detected hyperactivity in the hippocampus during task-related functional magnetic resonance imaging (fMRI). Such elevated activation has been localized to the hippocampal dentate gyrus/CA3 (DG/CA3) during performance of a tas...

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Bibliographic Details
Published in:	NeuroImage clinical Vol. 7; no. C; pp. 688 - 698
Main Authors:	Bakker, Arnold, Albert, Marilyn S., Krauss, Gregory, Speck, Caroline L., Gallagher, Michela
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Inc 01.01.2015 Elsevier
Subjects:	Aged Anticonvulsants - therapeutic use Cognitive Dysfunction - drug therapy Cognitive Dysfunction - physiopathology Cross-Over Studies Dentate gyrus Dentate Gyrus - drug effects Dentate Gyrus - physiopathology Entorhinal cortex Female fMRI Humans Image Processing, Computer-Assisted Levetiracetam Magnetic Resonance Imaging Male Memory Memory - drug effects Memory - physiology Middle Aged Mild cognitive impairment Neuropsychological Tests Piracetam - analogs & derivatives Piracetam - therapeutic use Radiology Regular Temporal Lobe - drug effects Temporal Lobe - physiopathology fMRI Dentate gyrus Mild cognitive impairment Entorhinal cortex Memory Levetiracetam
ISSN:	2213-1582, 2213-1582
Online Access:	Get full text
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