Placental DNA methylation signatures of maternal smoking during pregnancy and potential impacts on fetal growth

Maternal smoking during pregnancy (MSDP) contributes to poor birth outcomes, in part through disrupted placental functions, which may be reflected in the placental epigenome. Here we present a meta-analysis of the associations between MSDP and placental DNA methylation (DNAm) and between DNAm and bi...

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Bibliographic Details
Published in:	Nature communications Vol. 12; no. 1; pp. 5095 - 13
Main Authors:	Everson, Todd M., Vives-Usano, Marta, Seyve, Emie, Cardenas, Andres, Lacasaña, Marina, Craig, Jeffrey M., Lesseur, Corina, Baker, Emily R., Fernandez-Jimenez, Nora, Heude, Barbara, Perron, Patrice, Gónzalez-Alzaga, Beatriz, Halliday, Jane, Deyssenroth, Maya A., Karagas, Margaret R., Íñiguez, Carmen, Bouchard, Luigi, Carmona-Sáez, Pedro, Loke, Yuk J., Hao, Ke, Belmonte, Thalia, Charles, Marie A., Martorell-Marugán, Jordi, Muggli, Evelyne, Chen, Jia, Fernández, Mariana F., Tost, Jorg, Gómez-Martín, Antonio, London, Stephanie J., Sunyer, Jordi, Marsit, Carmen J., Lepeule, Johanna, Hivert, Marie-France, Bustamante, Mariona
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 24.08.2021 Nature Publishing Group Nature Portfolio
Subjects:	49 49/61 631/208/176 631/208/177 692/499 Biochemistry, Molecular Biology Birth Children Consortia Cord blood Deoxyribonucleic acid DNA DNA Methylation Epigenesis, Genetic Epigenetics Female Fetal Development - drug effects Fetal Development - genetics Fetuses Gene expression Genetic Heterogeneity Genetics Genomics Humanities and Social Sciences Humans Life Sciences multidisciplinary Nicotiana Nucleotide Motifs Placenta Placenta - metabolism Pregnancy Science Science (multidisciplinary) Smoking Smoking - adverse effects
ISSN:	2041-1723, 2041-1723
Online Access:	Get full text
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