Performance comparison of four types of target enrichment baits for exome DNA sequencing

Background Next-generation sequencing technology is developing rapidly and target capture sequencing has become an important technique. Several different platforms for library preparation and target capture with different bait types respectively are commercially available. Here we compare the perfor...

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Bibliographic Details
Published in:	Hereditas Vol. 158; no. 1; p. 10
Main Authors:	Zhou, Juan, Zhang, Mancang, Li, Xiaoqi, Wang, Zhuo, Pan, Dun, Shi, Yongyong
Format:	Journal Article
Language:	English
Published:	London BioMed Central 17.02.2021 Nature Publishing Group BMC
Subjects:	Animal Genetics and Genomics Bait type Biomedical and Life Sciences Coverage Deoxyribonucleic acid DNA DNA sequencing Double-stranded RNA Efficiency Evolutionary Biology Exome capture efficiency GC bias genome Genomes Life Sciences mutation Next-generation sequencing Ribonucleic acid RNA Single-nucleotide polymorphism single-stranded DNA SNPs and Indels detection Bait type SNPs and Indels detection Coverage Next-generation sequencing GC bias Exome capture efficiency
ISSN:	1601-5223, 0018-0661, 1601-5223
Online Access:	Get full text
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