Investigating the causal effects of childhood and adulthood adiposity on later life mental health outcome: a Mendelian randomization study

Background Obesity particularly during childhood is considered a global public health crisis and has been linked with later life health consequences including mental health. However, there is lack of causal understanding if childhood body size has a direct effect on mental health or has an indirect...

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Bibliographic Details
Published in:	BMC medicine Vol. 23; no. 1; pp. 4 - 9
Main Authors:	Pathak, Sweta, Richardson, Tom G., Sanderson, Eleanor, Åsvold, Bjørn Olav, Bhatta, Laxmi, Brumpton, Ben M.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 06.01.2025 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Adipose tissue Adiposity - genetics Adult Adulthood Adults Analysis Anxiety Anxiety - epidemiology Biobanks Biomedicine Body mass index Body size Care and treatment Causal inference Child Child & adolescent mental health Child psychopathology Childhood Children Complications and side effects Consortia Depression Depression - epidemiology Depression - genetics Diagnosis Estimates Female Genome-wide association studies Genome-Wide Association Study Humans Male Medicine Medicine & Public Health Mendelian randomization Mendelian Randomization Analysis Mental depression Mental disorders Mental Health Obesity Observational studies Public health Randomization Research Article Risk factors Risk reduction Software United Kingdom - epidemiology United Kingdom Norway United Kingdom > UK Obesity Depression Anxiety Adulthood Mendelian randomization Childhood
ISSN:	1741-7015, 1741-7015
Online Access:	Get full text
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