Breast cancer risk factors and their effects on survival: a Mendelian randomisation study

Background Observational studies have investigated the association of risk factors with breast cancer prognosis. However, the results have been conflicting and it has been challenging to establish causality due to potential residual confounding. Using a Mendelian randomisation (MR) approach, we aime...

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Bibliographic Details
Published in:	BMC medicine Vol. 18; no. 1; pp. 327 - 10
Main Authors:	Escala-Garcia, Maria, Morra, Anna, Canisius, Sander, Chang-Claude, Jenny, Kar, Siddhartha, Zheng, Wei, Bojesen, Stig E., Easton, Doug, Pharoah, Paul D. P., Schmidt, Marjanka K.
Format:	Journal Article
Language:	English
Published:	London BioMed Central 17.11.2020 BioMed Central Ltd Springer Nature B.V BMC
Subjects:	Age Biomedicine Body mass Body mass index Body size Breast cancer Breast cancer risk factors Breast cancer survival Breast Neoplasms - genetics Breast Neoplasms - mortality Confidence intervals Consortia Datasets Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Estrogen receptors Estrogens Female Genetic aspects Genomes GWAS Catalog Health risks Humans Liability Lifestyle Mammography Medical prognosis Medicine Medicine & Public Health Menarche Mendelian randomisation Mendelian Randomization Analysis - methods Menopause Physical activity Population Prognosis Randomization Research Article Risk analysis Risk Factors Sensitivity analysis Survival Survival Analysis Womens health Europe Lifestyle GWAS Catalog Breast cancer survival Mendelian randomisation Breast cancer risk factors
ISSN:	1741-7015, 1741-7015
Online Access:	Get full text
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