Neuroprotective effects of Withania somnifera in BPA induced-cognitive dysfunction and oxidative stress in mice

Background Bisphenol A (BPA), a major endocrine disruptor and a xenobiotic compound is used abundantly in the production of polycarbonate plastics and epoxy resins. Human exposure to this compound is primarily via its leaching from the protective internal epoxy resin coatings of containers into the...

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Bibliographic Details
Published in:	Behavioral and brain functions Vol. 15; no. 1; p. 9
Main Authors:	Birla, Hareram, Keswani, Chetan, Rai, Sachchida Nand, Singh, Saumitra Sen, Zahra, Walia, Dilnashin, Hagera, Rathore, Aaina Singh, Singh, Surya Pratap
Format:	Journal Article
Language:	English
Published:	London BioMed Central 07.05.2019 Springer Nature B.V BMC
Subjects:	Aging Albinism Animal cognition Animals Antioxidants Behavior Behavior, Animal - drug effects Behavioral Therapy Benzhydryl Compounds - adverse effects Beverages Biomarkers Biomedical and Life Sciences Biomedicine Bisphenol A Brain research Catalase Cognition Disorders - chemically induced Cognitive ability Cognitive Dysfunction - drug therapy Cognitive impairment Dental prosthetics Dental restorative materials Dental sealants Drug dosages Epoxy resins Estrogens Gene expression Glutamic acid receptors (ionotropic) Hippocampus Immunohistochemistry Laboratories Leaching Male Maze Learning - drug effects Medical research Memory Memory - drug effects Memory, Short-Term - drug effects Mice N-Methyl-D-aspartic acid receptors Neurodegenerative diseases Neurology Neuroprotection Neuroprotective Agents - pharmacology Neurosciences Neurotoxicity Oxidative stress Phenols - adverse effects Physiology Plant Extracts - pharmacology Polycarbonate Potassium Psychiatry Reactive oxygen species Receptor mechanisms Receptors, N-Methyl-D-Aspartate Short term memory Spatial discrimination learning Spatial Learning - drug effects Spatial memory Toxicology Withania - metabolism Withania somnifera United States > US India Biomarkers Oxidative stress Neurotoxicity Reactive oxygen species Cognitive impairment Spatial memory
ISSN:	1744-9081, 1744-9081
Online Access:	Get full text
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