Multiple Mechanisms of Unfolded Protein Response-Induced Cell Death

Eukaryotic cells fold and assemble membrane and secreted proteins in the endoplasmic reticulum (ER), before delivery to other cellular compartments or the extracellular environment. Correctly folded proteins are released from the ER, and poorly folded proteins are retained until they achieve stable...

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Vydáno v:	The American journal of pathology Ročník 185; číslo 7; s. 1800
Hlavní autoři:	Hiramatsu, Nobuhiko, Chiang, Wei-Chieh, Kurt, Timothy D, Sigurdson, Christina J, Lin, Jonathan H
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States 01.07.2015
Témata:	Animals Apoptosis Awards and Prizes eIF-2 Kinase - metabolism Endoplasmic Reticulum - metabolism Endoplasmic Reticulum Stress Endoribonucleases - metabolism Eukaryotic Cells - physiology Humans Mammals Models, Biological Molecular Chaperones - metabolism Pathology Protein Biosynthesis Protein Serine-Threonine Kinases - metabolism Signal Transduction Societies, Medical Unfolded Protein Response United States United States
ISSN:	1525-2191, 1525-2191
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