Prospective multicentre accuracy evaluation of the FUJIFILM SILVAMP TB LAM test for the diagnosis of tuberculosis in people living with HIV demonstrates lot-to-lot variability

There is an urgent need for rapid, non-sputum point-of-care diagnostics to detect tuberculosis. This prospective trial in seven high tuberculosis burden countries evaluated the diagnostic accuracy of the point-of-care urine-based lipoarabinomannan assay FUJIFILM SILVAMP TB LAM (FujiLAM) among inpati...

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Veröffentlicht in:	PloS one Jg. 19; H. 5; S. e0303846
Hauptverfasser:	Székely, Rita, Sossen, Bianca, Mukoka, Madalo, Muyoyeta, Monde, Nakabugo, Elizabeth, Hella, Jerry, Nguyen, Hung Van, Ubolyam, Sasiwimol, Chikamatsu, Kinuyo, Macé, Aurélien, Vermeulen, Marcia, Centner, Chad M., Nyangu, Sarah, Sanjase, Nsala, Sasamalo, Mohamed, Dinh, Huong Thi, Ngo, The Anh, Manosuthi, Weerawat, Jirajariyavej, Supunnee, Mitarai, Satoshi, Nguyen, Nhung Viet, Avihingsanon, Anchalee, Reither, Klaus, Nakiyingi, Lydia, Kerkhoff, Andrew D., MacPherson, Peter, Meintjes, Graeme, Denkinger, Claudia M., Ruhwald, Morten
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States Public Library of Science 31.05.2024 Public Library of Science (PLoS)
Schlagworte:	Accuracy Adult Analysis Antigens Biomarkers Blood Blood culture CD4 antigen Cell culture COVID-19 Decision making Diagnosis Diagnostic systems Diagnostic tests Female HIV HIV (Viruses) HIV Infections - complications HIV Infections - diagnosis HIV testing Human immunodeficiency virus Humans Lipopolysaccharides - urine Male Medical diagnosis Medical examination Microscopy Middle Aged Mycobacterium tuberculosis - isolation & purification Prospective Studies Quality control Sensitivity Sensitivity and Specificity Sputum Sputum - microbiology Trainers Tuberculosis Tuberculosis - diagnosis Urine Variability South Africa Vietnam Malawi United States > US Tanzania Uganda Zambia Thailand
ISSN:	1932-6203, 1932-6203
Online-Zugang:	Volltext
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