3D in vitro hydrogel models to study the human lung extracellular matrix and fibroblast function

The pulmonary extracellular matrix (ECM) is a macromolecular structure that provides mechanical support, stability and elastic recoil for different pulmonary cells including the lung fibroblasts. The ECM plays an important role in lung development, remodeling, repair, and the maintenance of tissue h...

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Bibliographic Details
Published in:	Respiratory research Vol. 24; no. 1; pp. 242 - 15
Main Authors:	Phogat, Sakshi, Thiam, Fama, Al Yazeedi, Safiya, Abokor, Filsan Ahmed, Osei, Emmanuel Twumasi
Format:	Journal Article
Language:	English
Published:	London BioMed Central 05.10.2023 BioMed Central Ltd Nature Publishing Group BMC
Subjects:	3D hydrogels Analysis Asthma Biomechanics Care and treatment Cell culture Chronic obstructive pulmonary disease Collagen Connective tissue Detergents Diagnosis ECM stiffness Extracellular matrix Extracellular matrix (ECM) Extracellular Matrix - metabolism Fibroblasts Fibroblasts - metabolism Fibronectin Fibrosis Gels (Pharmacy) Genotype & phenotype Health aspects Homeostasis Humans Hyaluronic acid Hydrogels Hydrogels - analysis Hydrogels - metabolism Idiopathic Pulmonary Fibrosis - metabolism Lung - metabolism Lung diseases Lung fibroblasts Macromolecules Medicine Medicine & Public Health Molecular structure Obstructive lung disease Phenotypes Pneumology/Respiratory System Polymers Proteins Repair Respiratory diseases Review Three dimensional models Canada Extracellular matrix (ECM) Lung fibroblasts ECM stiffness 3D hydrogels Fibrosis
ISSN:	1465-993X, 1465-9921, 1465-993X
Online Access:	Get full text
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