Prevention and management of CVD in LMICs: why do ethnicity, culture, and context matter?

Background Low- and middle-income countries now experience the highest prevalence and mortality rates of cardiovascular disease. Main text While improving the availability and delivery of proven, effective therapies will no doubt mitigate this burden, we posit that studies evaluating cardiovascular...

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Published in:BMC medicine Vol. 18; no. 1; pp. 7 - 5
Main Authors: Anand, Shuchi, Bradshaw, Christina, Prabhakaran, Dorairaj
Format: Journal Article
Language:English
Published: London BioMed Central 24.01.2020
BioMed Central Ltd
Springer Nature B.V
BMC
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ISSN:1741-7015, 1741-7015
Online Access:Get full text
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Summary:Background Low- and middle-income countries now experience the highest prevalence and mortality rates of cardiovascular disease. Main text While improving the availability and delivery of proven, effective therapies will no doubt mitigate this burden, we posit that studies evaluating cardiovascular disease risk factors, management strategies and service delivery, in diverse settings and diverse populations, are equally critical to improving outcomes in low- and middle-income countries. Focusing on examples drawn from four cardiovascular diseases — coronary artery disease, stroke, diabetes and kidney disease — we argue that ethnicity, culture and context matter in determining the risk factors for disease as well as the comparative effectiveness of medications and other interventions, particularly diet and lifestyle interventions. Conclusion We believe that a host of cohort studies and randomized control trials currently being conducted or planned in low- and middle-income countries, focusing on previously understudied race/ethnic groups, have the potential to increase knowledge about the cause(s) and management of cardiovascular diseases across the world.
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ISSN:1741-7015
1741-7015
DOI:10.1186/s12916-019-1480-9