ROTS: An R package for reproducibility-optimized statistical testing

Differential expression analysis is one of the most common types of analyses performed on various biological data (e.g. RNA-seq or mass spectrometry proteomics). It is the process that detects features, such as genes or proteins, showing statistically significant differences between the sample group...

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Bibliographic Details
Published in:	PLoS computational biology Vol. 13; no. 5; p. e1005562
Main Authors:	Suomi, Tomi, Seyednasrollah, Fatemeh, Jaakkola, Maria K., Faux, Thomas, Elo, Laura L.
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 01.05.2017 Public Library of Science (PLoS)
Subjects:	Bioinformatics Biology Biology and Life Sciences Biotechnology Case studies Cells, Cultured Chromatography Computational Biology - methods Computer and Information Sciences Consortia Datasets Funding Gene expression Genes Genomes Humans Internet Mass Spectrometry Mass spectroscopy Methods Models, Statistical Packages Physical Sciences Proteins Proteins - chemistry Proteomics Ranking Repositories Reproducibility Reproducibility of Results Research and Analysis Methods Ribonucleic acid RNA Scientific imaging Sequence Analysis, RNA Software State of the art Statistical analysis Statistical models Statistical tests Statistics Transcription Water analysis Finland
ISSN:	1553-7358, 1553-734X, 1553-7358
Online Access:	Get full text
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