Myostatin is associated with the presence and development of acute-on-chronic liver failure

Acute-on-chronic liver failure (ACLF) has been linked to different pathophysiological mechanisms, including systemic inflammation and mitochondrial dysfunction. Sarcopenia has also been proposed as a potential mechanism; myostatin is a key factor inducing sarcopenia. Therefore, this study aimed to e...

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Bibliographic Details
Published in:	JHEP reports Vol. 5; no. 8; p. 100761
Main Authors:	Ruiz-Margáin, Astrid, Pohlmann, Alessandra, Lanzerath, Silke, Langheinrich, Melanie, Campos-Murguía, Alejandro, Román-Calleja, Berenice M., Schierwagen, Robert, Klein, Sabine, Uschner, Frank Erhard, Brol, Maximilian Joseph, Torre-Delgadillo, Aldo, Flores-García, Nayelli C., Praktiknjo, Michael, Macías Rodríguez, Ricardo U., Trebicka, Jonel
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier B.V 01.08.2023 Elsevier
Subjects:	ACLF cirrhosis Gastroenterology and Hepatology liver failure malnutrition myostatin sarcopenia ACLF AD IL ROC PhA MAMC myostatin AUC malnutrition liver failure MELD TST HGS OF CLIF-C cirrhosis sarcopenia handgrip strength area under the ROC curve receiver-operating characteristic triceps skinfold thickness Chronic Liver Failure – consortium phase angle interleukin mid-arm muscle circumference model for end-stage liver disease acute-on-chronic liver failure organ failure acute decompensation
ISSN:	2589-5559, 2589-5559
Online Access:	Get full text
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