Polymorphism discovery and allele frequency estimation using high-throughput DNA sequencing of target-enriched pooled DNA samples

Background The central role of the somatotrophic axis in animal post-natal growth, development and fertility is well established. Therefore, the identification of genetic variants affecting quantitative traits within this axis is an attractive goal. However, large sample numbers are a pre-requisite...

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Bibliographic Details
Published in:	BMC genomics Vol. 13; no. 1; p. 16
Main Authors:	Mullen, Michael P, Creevey, Christopher J, Berry, Donagh P, McCabe, Matt S, Magee, David A, Howard, Dawn J, Killeen, Aideen P, Park, Stephen D, McGettigan, Paul A, Lucy, Matt C, MacHugh, David E, Waters, Sinead M
Format:	Journal Article
Language:	English
Published:	London BioMed Central 11.01.2012 BioMed Central Ltd BMC
Subjects:	Animal Genetics and Genomics Animals Base Sequence Binding Sites Biomedical and Life Sciences Cattle DNA sequencing Fertility - genetics Fertility, Human Gene Frequency Genetic aspects Genetic polymorphisms Genomics High-Throughput Nucleotide Sequencing Life Sciences Microarrays Microbial Genetics and Genomics MicroRNAs - metabolism Non-human and non-rodent vertebrate genomic Nucleotide sequencing Plant Genetics and Genomics Polymorphism, Single Nucleotide Proteomics Quantitative trait loci Reproducibility of Results Research Article Sequence Analysis, DNA Transcription Factors - metabolism Ireland Growth Hormone Receptor Growth Hormone Release Hormone Allele Frequency Estimation Quantitative Trait Nucleotide Genetic Merit
ISSN:	1471-2164, 1471-2164
Online Access:	Get full text
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