STED nanoscopy of actin dynamics in synapses deep inside living brain slices

It is difficult to investigate the mechanisms that mediate long-term changes in synapse function because synapses are small and deeply embedded inside brain tissue. Although recent fluorescence nanoscopy techniques afford improved resolution, they have so far been restricted to dissociated cells or...

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Bibliographic Details

Published in:	Biophysical journal Vol. 101; no. 5; p. 1277
Main Authors:	Urban, Nicolai T, Willig, Katrin I, Hell, Stefan W, Nägerl, U Valentin
Format:	Journal Article
Language:	English
Published:	United States 07.09.2011
Subjects:	Actins - metabolism Animals Brain - cytology Brain - metabolism Cell Survival Dendritic Spines - metabolism Mice Mice, Inbred C57BL Microscopy, Fluorescence - methods Nanotechnology - methods Synapses - metabolism
ISSN:	1542-0086, 1542-0086
Online Access:	Get more information
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