STED nanoscopy of actin dynamics in synapses deep inside living brain slices

It is difficult to investigate the mechanisms that mediate long-term changes in synapse function because synapses are small and deeply embedded inside brain tissue. Although recent fluorescence nanoscopy techniques afford improved resolution, they have so far been restricted to dissociated cells or...

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Vydané v:	Biophysical journal Ročník 101; číslo 5; s. 1277
Hlavní autori:	Urban, Nicolai T, Willig, Katrin I, Hell, Stefan W, Nägerl, U Valentin
Médium:	Journal Article
Jazyk:	English
Vydavateľské údaje:	United States 07.09.2011
Predmet:	Actins - metabolism Animals Brain - cytology Brain - metabolism Cell Survival Dendritic Spines - metabolism Mice Mice, Inbred C57BL Microscopy, Fluorescence - methods Nanotechnology - methods Synapses - metabolism
ISSN:	1542-0086, 1542-0086
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