Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome
Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elucidation uncovered novel resolution phase mediators in vivo...
Gespeichert in:
| Veröffentlicht in: | Biochimica et biophysica acta Jg. 1851; H. 4; S. 397 - 413 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
Netherlands
Elsevier B.V
01.04.2015
|
| Schlagworte: | |
| ISSN: | 1388-1981, 0006-3002, 1879-2618 |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Abstract | Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elucidation uncovered novel resolution phase mediators in vivo that stimulate endogenous resolution mechanisms in inflammation. Resolving inflammatory exudates and human leukocytes utilize DHA and other n−3 EFA to produce three structurally distinct families of potent di- and trihydroxy-containing products, with several stereospecific potent mediators in each family. Given their potent and stereoselective picogram actions, specific members of these new families of mediators from the DHA metabolome were named D-series resolvins (Resolvin D1 to Resolvin D6), protectins (including protectin D1–neuroprotectin D1), and maresins (MaR1 and MaR2). In this review, we focus on a) biosynthesis of protectins and maresins as anti-inflammatory–pro-resolving mediators; b) their complete stereochemical assignments and actions in vivo in disease models. Each pathway involves the biosynthesis of epoxide-containing intermediates produced from hydroperoxy-containing precursors from human leukocytes and within exudates. Also, aspirin triggers an endogenous DHA metabolome that biosynthesizes potent products in inflammatory exudates and human leukocytes, namely aspirin-triggered Neuroprotectin D1/Protectin D1 [AT-(NPD1/PD1)]. Identification and structural elucidation of these new families of bioactive mediators in resolution has opened the possibility of diverse patho-physiologic actions in several processes including infection, inflammatory pain, tissue regeneration, neuroprotection-neurodegenerative disorders, wound healing, and others. This article is part of a Special Issue entitled “Oxygenated metabolism of PUFA: analysis and biological relevance”.
•Proresolving mediators are biosynthesized during resolution phase of acute inflammation.•Resolution is a biosynthetically active process.•Protectins and maresins are two structurally distinct families of potent local mediators.•NPD1/PD1 reduces neural inflammation, stimulates resolution and reduces pain.•MaR1 stimulates tissue regeneration and resolution mechanisms, is anti-inflammatory and reduces pain. |
|---|---|
| AbstractList | Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elucidation uncovered novel resolution phase mediators in vivo that stimulate endogenous resolution mechanisms in inflammation. Resolving inflammatory exudates and human leukocytes utilize DHA and other n−3 EFA to produce three structurally distinct families of potent di- and trihydroxy-containing products, with several stereospecific potent mediators in each family. Given their potent and stereoselective picogram actions, specific members of these new families of mediators from the DHA metabolome were named D-series resolvins (Resolvin D1 to Resolvin D6), protectins (including protectin D1–neuroprotectin D1), and maresins (MaR1 and MaR2). In this review, we focus on a) biosynthesis of protectins and maresins as anti-inflammatory–pro-resolving mediators; b) their complete stereochemical assignments and actions in vivo in disease models. Each pathway involves the biosynthesis of epoxide-containing intermediates produced from hydroperoxy-containing precursors from human leukocytes and within exudates. Also, aspirin triggers an endogenous DHA metabolome that biosynthesizes potent products in inflammatory exudates and human leukocytes, namely aspirin-triggered Neuroprotectin D1/Protectin D1 [AT-(NPD1/PD1)]. Identification and structural elucidation of these new families of bioactive mediators in resolution has opened the possibility of diverse patho-physiologic actions in several processes including infection, inflammatory pain, tissue regeneration, neuroprotection-neurodegenerative disorders, wound healing, and others. This article is part of a Special Issue entitled “Oxygenated metabolism of PUFA: analysis and biological relevance”.
•Proresolving mediators are biosynthesized during resolution phase of acute inflammation.•Resolution is a biosynthetically active process.•Protectins and maresins are two structurally distinct families of potent local mediators.•NPD1/PD1 reduces neural inflammation, stimulates resolution and reduces pain.•MaR1 stimulates tissue regeneration and resolution mechanisms, is anti-inflammatory and reduces pain. Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elucidation uncovered novel resolution phase mediators in vivo that stimulate endogenous resolution mechanisms in inflammation. Resolving inflammatory exudates and human leukocytes utilize DHA and other n-3 EFA to produce three structurally distinct families of potent di- and trihydroxy-containing products, with several stereospecific potent mediators in each family. Given their potent and stereoselective picogram actions, specific members of these new families of mediators from the DHA metabolome were named D-series resolvins (Resolvin D1 to Resolvin D6), protectins (including protectin D1-neuroprotectin D1), and maresins (MaR1 and MaR2). In this review, we focus on a) biosynthesis of protectins and maresins as anti-inflammatory-pro-resolving mediators; b) their complete stereochemical assignments and actions in vivo in disease models. Each pathway involves the biosynthesis of epoxide-containing intermediates produced from hydroperoxy-containing precursors from human leukocytes and within exudates. Also, aspirin triggers an endogenous DHA metabolome that biosynthesizes potent products in inflammatory exudates and human leukocytes, namely aspirin-triggered Neuroprotectin D1/Protectin D1 [AT-(NPD1/PD1)]. Identification and structural elucidation of these new families of bioactive mediators in resolution has opened the possibility of diverse patho-physiologic actions in several processes including infection, inflammatory pain, tissue regeneration, neuroprotection-neurodegenerative disorders, wound healing, and others. This article is part of a Special Issue entitled "Oxygenated metabolism of PUFA: analysis and biological relevance".Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elucidation uncovered novel resolution phase mediators in vivo that stimulate endogenous resolution mechanisms in inflammation. Resolving inflammatory exudates and human leukocytes utilize DHA and other n-3 EFA to produce three structurally distinct families of potent di- and trihydroxy-containing products, with several stereospecific potent mediators in each family. Given their potent and stereoselective picogram actions, specific members of these new families of mediators from the DHA metabolome were named D-series resolvins (Resolvin D1 to Resolvin D6), protectins (including protectin D1-neuroprotectin D1), and maresins (MaR1 and MaR2). In this review, we focus on a) biosynthesis of protectins and maresins as anti-inflammatory-pro-resolving mediators; b) their complete stereochemical assignments and actions in vivo in disease models. Each pathway involves the biosynthesis of epoxide-containing intermediates produced from hydroperoxy-containing precursors from human leukocytes and within exudates. Also, aspirin triggers an endogenous DHA metabolome that biosynthesizes potent products in inflammatory exudates and human leukocytes, namely aspirin-triggered Neuroprotectin D1/Protectin D1 [AT-(NPD1/PD1)]. Identification and structural elucidation of these new families of bioactive mediators in resolution has opened the possibility of diverse patho-physiologic actions in several processes including infection, inflammatory pain, tissue regeneration, neuroprotection-neurodegenerative disorders, wound healing, and others. This article is part of a Special Issue entitled "Oxygenated metabolism of PUFA: analysis and biological relevance". Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elucidation uncovered novel resolution phase mediators in vivo that stimulate endogenous resolution mechanisms in inflammation. Resolving inflammatory exudates and human leukocytes utilize DHA and other n-3 EFA to produce three structurally distinct families of potent di- and trihydroxy-containing products, with several stereospecific potent mediators in each family. Given their potent and stereoselective picogram actions, specific members of these new families of mediators from the DHA metabolome were named D-series resolvins (Resolvin D1 to Resolvin D6), protectins (including protectin D1-neuroprotectin D1), and maresins (MaR1 and MaR2). In this review, we focus on a) biosynthesis of protectins and maresins as anti-inflammatory-pro-resolving mediators; b) their complete stereochemical assignments and actions in vivo in disease models. Each pathway involves the biosynthesis of epoxide-containing intermediates produced from hydroperoxy-containing precursors from human leukocytes and within exudates. Also, aspirin triggers an endogenous DHA metabolome that biosynthesizes potent products in inflammatory exudates and human leukocytes, namely aspirin-triggered Neuroprotectin D1/Protectin D1 [AT-(NPD1/PD1)]. Identification and structural elucidation of these new families of bioactive mediators in resolution has opened the possibility of diverse patho-physiologic actions in several processes including infection, inflammatory pain, tissue regeneration, neuroprotection-neurodegenerative disorders, wound healing, and others. This article is part of a Special Issue entitled "Oxygenated metabolism of PUFA: analysis and biological relevance". Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to investigate self-limited (self-resolving) inflammatory exudates in mice and structural elucidation uncovered novel resolution phase mediators in vivo that stimulate endogenous resolution mechanisms in inflammation. Resolving inflammatory exudates and human leukocytes utilize DHA and other n−3 EFA to produce three structurally distinct families of potent di- and trihydroxy-containing products, with several stereospecific potent mediators in each family. Given their potent and stereoselective picogram actions, specific members of these new families of mediators from the DHA metabolome were named D-series resolvins (Resolvin D1 to Resolvin D6), protectins (including protectin D1–neuroprotectin D1), and maresins (MaR1 and MaR2). In this review, we focus on a) biosynthesis of protectins and maresins as anti-inflammatory–pro-resolving mediators; b) their complete stereochemical assignments and actions in vivo in disease models. Each pathway involves the biosynthesis of epoxide-containing intermediates produced from hydroperoxy-containing precursors from human leukocytes and within exudates. Also, aspirin triggers an endogenous DHA metabolome that biosynthesizes potent products in inflammatory exudates and human leukocytes, namely aspirin-triggered Neuroprotectin D1/Protectin D1 [AT-(NPD1/PD1)]. Identification and structural elucidation of these new families of bioactive mediators in resolution has opened the possibility of diverse patho-physiologic actions in several processes including infection, inflammatory pain, tissue regeneration, neuroprotection-neurodegenerative disorders, wound healing, and others. This article is part of a Special Issue entitled “Oxygenated metabolism of PUFA: analysis and biological relevance”. |
| Author | Chiang, Nan Dalli, Jesmond Winkler, Jeremy W. Serhan, Charles N. Colas, Romain A. |
| Author_xml | – sequence: 1 givenname: Charles N. surname: Serhan fullname: Serhan, Charles N. email: cnserhan@zeus.bwh.harvard.edu – sequence: 2 givenname: Jesmond surname: Dalli fullname: Dalli, Jesmond – sequence: 3 givenname: Romain A. surname: Colas fullname: Colas, Romain A. – sequence: 4 givenname: Jeremy W. surname: Winkler fullname: Winkler, Jeremy W. – sequence: 5 givenname: Nan surname: Chiang fullname: Chiang, Nan |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25139562$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkUtv3CAUhVGUKu9_UFVedmP3AjaGLCpVUV9S1HbRrhHGl4qRbaaAJ2p_fZmZZNNFs4F7pXMO4nyX5HQJCxLykkJDgYo3m2YYzOS3DQPaNiAbAHFCLqjsVc0Eladl5lLWVEl6Ti5T2gDQjvPujJyzjnLVCXZB_nyLIaPNfkmVWcZqNhFTWW6rL_hQbWOoyx6mnV9-Vs7MfvKYquCqGUdvcoip8ktl7JqxDG4y82yyD8sh6-BcD-vggymP7LAYsxnCFGa8Ji-cmRLePN5X5MeH99_vPtX3Xz9-vnt3X1vBWa5Fz62zSnC0yLm1fFQorBVOIbQdVz0b5MjlQHvunDFgpbKSKWZaJ9XIDL8ir4-55Te_VkxZzz5ZnCazYFiTZgDAOUArnpXSHgSDcuylrx6l61DK0NvoS3e_9VO1RXB7FNgYUorotPX5UE6Oxk-agt5z1Bt95Kj3HDVIXTgWc_uP-Sn_Gdvbow1LnzuPUSfrcbEFViyQ9Rj8_wP-AiGpu1E |
| CitedBy_id | crossref_primary_10_1177_0148607116640275 crossref_primary_10_2174_0113892010310578240926051158 crossref_primary_10_3390_metabo10060264 crossref_primary_10_1016_j_bbi_2015_12_009 crossref_primary_10_1073_pnas_2023285119 crossref_primary_10_3390_molecules29204821 crossref_primary_10_1038_s41467_021_22370_2 crossref_primary_10_1080_10408398_2025_2486267 crossref_primary_10_1038_srep39571 crossref_primary_10_1016_j_phymed_2019_152881 crossref_primary_10_1159_000447498 crossref_primary_10_1002_lary_29337 crossref_primary_10_1016_j_expneurol_2025_115226 crossref_primary_10_1016_j_bcp_2022_115330 crossref_primary_10_1016_j_lpm_2018_03_011 crossref_primary_10_1016_j_mam_2018_03_004 crossref_primary_10_3390_nu16223937 crossref_primary_10_1017_S0007114521002294 crossref_primary_10_1016_j_hnm_2024_200269 crossref_primary_10_1016_j_prostaglandins_2020_106426 crossref_primary_10_3390_ijms242115528 crossref_primary_10_1172_JCI76693 crossref_primary_10_3390_molecules28124728 crossref_primary_10_1186_s12974_022_02386_1 crossref_primary_10_3390_biom12010075 crossref_primary_10_3390_nu9040325 crossref_primary_10_1177_17534259211057038 crossref_primary_10_1002_ardp_202100367 crossref_primary_10_1016_j_bbalip_2015_10_001 crossref_primary_10_1016_j_isci_2023_108502 crossref_primary_10_1007_s00216_018_1222_4 crossref_primary_10_1016_j_clnu_2017_02_021 crossref_primary_10_1007_s12035_018_1136_3 crossref_primary_10_1155_2016_8239258 crossref_primary_10_3389_fonc_2019_01399 crossref_primary_10_1038_s41392_021_00658_5 crossref_primary_10_1186_s12944_019_1049_9 crossref_primary_10_1371_journal_pone_0171249 crossref_primary_10_1177_0148607115595974 crossref_primary_10_1002_jpen_2634 crossref_primary_10_3390_ijms25105408 crossref_primary_10_1016_j_biochi_2019_11_016 crossref_primary_10_1016_j_biochi_2023_04_005 crossref_primary_10_1016_j_jsps_2023_101802 crossref_primary_10_3390_ijms24021637 crossref_primary_10_1016_j_phrs_2018_10_026 crossref_primary_10_1042_EBC20200018 crossref_primary_10_3389_falgy_2025_1608202 crossref_primary_10_1007_s00011_023_01770_8 crossref_primary_10_1007_s00216_014_8369_4 crossref_primary_10_1016_j_coi_2017_10_007 crossref_primary_10_1186_s12967_023_04283_4 crossref_primary_10_1007_s11745_017_4292_8 crossref_primary_10_3892_mmr_2018_8583 crossref_primary_10_1080_16070658_2018_1465652 crossref_primary_10_1097_MOH_0000000000000822 crossref_primary_10_1016_j_jss_2020_06_062 crossref_primary_10_1002_efd2_70062 crossref_primary_10_1016_j_mce_2019_04_016 crossref_primary_10_1016_j_plipres_2021_101110 crossref_primary_10_1038_s41569_023_00984_x crossref_primary_10_1172_JCI129448 crossref_primary_10_3390_antiox13080982 crossref_primary_10_1093_advances_nmac064 crossref_primary_10_1002_lipd_12090 crossref_primary_10_3390_nu15040821 crossref_primary_10_1002_bmc_4402 crossref_primary_10_1667_RR14473_1 crossref_primary_10_1172_JCI97943 crossref_primary_10_1002_j_2040_4603_2019_tb00057_x crossref_primary_10_1016_j_jnutbio_2018_09_017 crossref_primary_10_1038_s41401_022_00944_0 crossref_primary_10_1146_annurev_food_032818_121316 crossref_primary_10_1172_JCI89429 crossref_primary_10_1016_j_bbalip_2019_158550 crossref_primary_10_1016_j_ijdevneu_2019_10_004 crossref_primary_10_1186_s11658_025_00756_0 crossref_primary_10_1007_s12013_023_01187_4 crossref_primary_10_3390_ph14111123 crossref_primary_10_4103_0366_6999_229890 crossref_primary_10_1016_j_oooo_2021_01_020 crossref_primary_10_1038_s41598_020_77386_3 crossref_primary_10_1007_s40266_022_00960_z crossref_primary_10_1186_s12950_021_00271_x crossref_primary_10_3389_fphar_2022_997403 crossref_primary_10_1016_j_biochi_2018_08_009 crossref_primary_10_1016_j_jff_2021_104465 crossref_primary_10_1016_j_prostaglandins_2023_106737 crossref_primary_10_1096_fj_201801957R crossref_primary_10_1111_jvim_16419 crossref_primary_10_1111_apha_70062 crossref_primary_10_3233_JAD_150367 crossref_primary_10_1096_fj_201700065R crossref_primary_10_1016_j_aca_2018_01_044 crossref_primary_10_1089_ars_2019_7751 crossref_primary_10_3390_jfb14040223 crossref_primary_10_3390_ani14040579 crossref_primary_10_3390_biom11070937 crossref_primary_10_1016_j_aquatox_2016_07_002 crossref_primary_10_1016_j_phymed_2021_153712 crossref_primary_10_3390_ph17040437 crossref_primary_10_1155_2018_2380319 crossref_primary_10_1021_jasms_4c00211 crossref_primary_10_1016_j_ajpath_2015_12_012 crossref_primary_10_1007_s11064_020_03050_x crossref_primary_10_3390_ijms22052465 crossref_primary_10_1016_j_jad_2023_02_016 crossref_primary_10_3389_fimmu_2022_934040 crossref_primary_10_17116_anaesthesiology202403158 crossref_primary_10_3390_toxins13120852 crossref_primary_10_3389_fcimb_2022_870398 crossref_primary_10_3389_fmicb_2018_01961 crossref_primary_10_1111_nbu_12726 crossref_primary_10_1038_s41598_017_05433_7 crossref_primary_10_1186_s12944_020_01343_2 crossref_primary_10_1016_j_biochi_2017_01_002 crossref_primary_10_1084_jem_20141904 crossref_primary_10_1186_s13063_021_05702_x crossref_primary_10_13005_bbra_3305 crossref_primary_10_1177_1744806916636386 crossref_primary_10_3389_fncel_2021_673549 crossref_primary_10_3390_biom12030353 crossref_primary_10_3390_ijms23116233 crossref_primary_10_1111_joim_12871 crossref_primary_10_1515_revneuro_2017_0074 crossref_primary_10_1096_fj_202001145R crossref_primary_10_3389_fncel_2017_00192 crossref_primary_10_1016_j_smim_2022_101597 crossref_primary_10_1016_j_ejphar_2025_177924 crossref_primary_10_1016_j_jep_2020_113146 crossref_primary_10_1002_mnfr_202400752 crossref_primary_10_1016_j_prostaglandins_2017_06_003 crossref_primary_10_1007_s12035_017_0681_5 crossref_primary_10_1186_s13054_024_04803_8 crossref_primary_10_1016_j_jlr_2025_100861 crossref_primary_10_1016_j_mam_2017_08_002 crossref_primary_10_1074_jbc_M117_801472 crossref_primary_10_1111_aej_12256 crossref_primary_10_33549_physiolres_933694 crossref_primary_10_1523_JNEUROSCI_1395_17_2017 crossref_primary_10_1016_j_preteyeres_2018_12_003 crossref_primary_10_1038_nri_2015_4 crossref_primary_10_1016_j_ejphar_2015_11_002 crossref_primary_10_1172_JCI122203 crossref_primary_10_3390_pathophysiology32020026 crossref_primary_10_3390_ijms24108838 crossref_primary_10_1002_art_41537 crossref_primary_10_1007_s12016_020_08796_4 crossref_primary_10_3390_molecules20023020 crossref_primary_10_1016_j_plipres_2022_101165 crossref_primary_10_1074_jbc_R117_783076 crossref_primary_10_1093_ajcn_nqab195 crossref_primary_10_3389_fphar_2022_816062 crossref_primary_10_3390_ijms221910370 crossref_primary_10_1007_s11357_023_00789_3 crossref_primary_10_1007_s12035_016_0138_2 crossref_primary_10_3390_nu12103198 crossref_primary_10_1002_jcp_27836 crossref_primary_10_1172_JCI77398 crossref_primary_10_1016_j_ejmech_2017_07_018 crossref_primary_10_1016_j_steroids_2015_02_003 crossref_primary_10_1016_j_biochi_2019_01_022 crossref_primary_10_1038_s41582_023_00777_3 crossref_primary_10_3389_fnins_2020_00831 crossref_primary_10_1007_s10787_023_01343_5 crossref_primary_10_1007_s11869_018_0586_0 crossref_primary_10_1155_2020_3813250 crossref_primary_10_1038_s41598_017_10382_2 crossref_primary_10_1002_jcp_25191 crossref_primary_10_1016_j_mehy_2020_110340 crossref_primary_10_1016_j_mam_2017_03_007 crossref_primary_10_1016_j_prostaglandins_2024_106944 crossref_primary_10_1016_j_mam_2017_03_005 crossref_primary_10_1016_j_molliq_2020_115206 crossref_primary_10_1146_annurev_physiol_020924_033209 crossref_primary_10_1186_s12974_016_0580_0 crossref_primary_10_1016_j_pharmthera_2020_107529 crossref_primary_10_1007_s13668_017_0215_9 crossref_primary_10_1016_j_mam_2017_03_001 crossref_primary_10_3390_nu13062061 crossref_primary_10_1073_pnas_1604029113 crossref_primary_10_1186_s12931_021_01792_y crossref_primary_10_1016_j_prostaglandins_2023_106787 crossref_primary_10_1186_s12974_022_02405_1 crossref_primary_10_5604_01_3001_0014_8986 crossref_primary_10_3389_fimmu_2023_1124774 crossref_primary_10_1016_j_plefa_2020_102185 crossref_primary_10_1152_ajpheart_00201_2017 crossref_primary_10_1016_j_jnutbio_2017_09_018 crossref_primary_10_1152_japplphysiol_01119_2016 crossref_primary_10_1016_j_freeradbiomed_2018_01_034 crossref_primary_10_1016_j_biopha_2022_113980 crossref_primary_10_1016_j_jshs_2019_12_003 crossref_primary_10_1096_fj_202100073R crossref_primary_10_1016_j_schres_2017_10_013 crossref_primary_10_1002_mnfr_201700479 crossref_primary_10_1155_2019_2309175 crossref_primary_10_1042_EBC20190082 crossref_primary_10_1096_fj_201601222R crossref_primary_10_20517_2574_1209_2025_40 crossref_primary_10_5493_wjem_v12_i1_1 crossref_primary_10_1016_j_exer_2017_06_015 crossref_primary_10_2147_NDS_S298870 crossref_primary_10_1016_j_plefa_2017_06_006 crossref_primary_10_1038_s41598_018_20108_7 crossref_primary_10_1016_j_mam_2018_09_003 crossref_primary_10_1016_j_smim_2018_09_002 crossref_primary_10_1016_j_expneurol_2020_113495 crossref_primary_10_1111_wrr_13151 crossref_primary_10_12998_wjcc_v4_i7_155 crossref_primary_10_1051_ocl_2015064 crossref_primary_10_3390_ijms242115693 crossref_primary_10_1016_j_bmcl_2017_03_079 crossref_primary_10_1093_advances_nmab013 crossref_primary_10_3390_ijms21165783 crossref_primary_10_3389_fphar_2020_00612 crossref_primary_10_3390_ijms23094635 crossref_primary_10_1002_mnfr_201801076 crossref_primary_10_1016_j_prostaglandins_2020_106483 crossref_primary_10_1155_2022_4589191 crossref_primary_10_2217_fnl_15_25 crossref_primary_10_1016_j_bcp_2023_115437 crossref_primary_10_3390_jox15040111 crossref_primary_10_1017_S0029665121003700 crossref_primary_10_1007_s00586_023_07725_1 crossref_primary_10_1016_j_ygcen_2016_07_006 crossref_primary_10_1016_j_nbd_2020_105061 crossref_primary_10_3390_nu11051076 crossref_primary_10_14814_phy2_16178 crossref_primary_10_3389_fphar_2017_00551 crossref_primary_10_1038_s41598_021_86284_1 crossref_primary_10_3389_fphys_2021_688946 crossref_primary_10_3390_ijms22094356 crossref_primary_10_3390_antiox10020313 crossref_primary_10_3390_ijms23094501 crossref_primary_10_3390_cells9112473 crossref_primary_10_3389_fimmu_2022_957518 crossref_primary_10_1016_j_cels_2016_09_009 crossref_primary_10_1016_j_biochi_2016_07_013 crossref_primary_10_1016_j_aquaculture_2024_741073 crossref_primary_10_1016_j_jlr_2023_100458 crossref_primary_10_1177_13872877251374353 crossref_primary_10_1016_j_bbalip_2025_159629 crossref_primary_10_1111_bph_14507 crossref_primary_10_1002_jpen_1759 crossref_primary_10_1002_mbo3_775 crossref_primary_10_1007_s12035_020_02118_7 crossref_primary_10_1002_jpen_1756 crossref_primary_10_3389_fphys_2020_00083 crossref_primary_10_3945_an_114_007732 crossref_primary_10_3390_nu13030824 crossref_primary_10_1051_fopen_2018008 crossref_primary_10_1093_intimm_dxz001 crossref_primary_10_3390_biomedicines12102221 crossref_primary_10_1096_fj_201802509R crossref_primary_10_1186_s40169_017_0158_1 crossref_primary_10_2174_011570159X365720250225080257 crossref_primary_10_1016_j_bbalip_2016_03_015 crossref_primary_10_1039_D0FO01445A crossref_primary_10_1080_08830185_2021_1974856 crossref_primary_10_1016_j_jfca_2019_103283 crossref_primary_10_1007_s11274_024_04032_9 crossref_primary_10_1080_10408398_2018_1544542 crossref_primary_10_1007_s11605_016_3333_6 crossref_primary_10_2754_avb201887040309 crossref_primary_10_3390_metabo14060314 crossref_primary_10_1016_j_avb_2019_101347 crossref_primary_10_4103_bc_bc_36_20 crossref_primary_10_3389_fimmu_2018_03161 crossref_primary_10_1186_s12931_022_02301_5 crossref_primary_10_1038_s41598_021_93817_1 crossref_primary_10_1002_jpen_1746 crossref_primary_10_1007_s10571_015_0206_6 crossref_primary_10_3390_cancers12082060 crossref_primary_10_1113_JP285929 crossref_primary_10_3389_fmicb_2020_587725 crossref_primary_10_1080_1028415X_2018_1500198 crossref_primary_10_1111_jphp_12744 crossref_primary_10_1002_lipd_12055 crossref_primary_10_1016_j_ejphar_2015_08_050 crossref_primary_10_1002_ncp_11278 crossref_primary_10_1016_j_plefa_2025_102682 crossref_primary_10_1007_s11894_018_0647_4 crossref_primary_10_3390_ijms23179918 crossref_primary_10_3945_an_115_009084 crossref_primary_10_1016_j_pnpbp_2017_12_008 crossref_primary_10_1038_s41583_020_0263_9 crossref_primary_10_3390_nu15040871 crossref_primary_10_3389_fphar_2021_746470 crossref_primary_10_1016_j_jlr_2024_100734 crossref_primary_10_1016_j_tetlet_2018_02_029 crossref_primary_10_1016_j_biochi_2016_12_012 crossref_primary_10_1016_j_bbalip_2017_04_001 crossref_primary_10_3390_nu15153317 crossref_primary_10_1016_j_heliyon_2024_e41152 crossref_primary_10_3390_ijms231810719 crossref_primary_10_1177_15347354241243024 crossref_primary_10_3390_nu8020099 crossref_primary_10_1002_mnfr_201900824 crossref_primary_10_1007_s10555_018_9743_z crossref_primary_10_1155_2015_830930 crossref_primary_10_3390_ijms23042121 crossref_primary_10_1016_j_mehy_2020_109813 crossref_primary_10_1186_s12944_024_02207_9 crossref_primary_10_3389_fimmu_2020_01356 crossref_primary_10_3390_ijms242417175 crossref_primary_10_1007_s40137_023_00367_8 crossref_primary_10_1089_ars_2020_8022 crossref_primary_10_1177_1535370215618462 crossref_primary_10_1016_j_jff_2024_106439 crossref_primary_10_1080_14728222_2017_1364363 crossref_primary_10_1002_jcp_29846 crossref_primary_10_1016_j_pharmthera_2017_07_007 crossref_primary_10_1080_1028415X_2024_2404782 crossref_primary_10_1007_s00784_023_05174_0 crossref_primary_10_1016_j_chemphyslip_2017_04_002 crossref_primary_10_3389_fnut_2022_998291 crossref_primary_10_1016_j_prostaglandins_2018_05_005 crossref_primary_10_1016_j_clnu_2017_07_004 crossref_primary_10_3390_nu12123615 crossref_primary_10_3389_fimmu_2022_1023999 crossref_primary_10_1111_jre_12861 crossref_primary_10_4049_jimmunol_1800806 crossref_primary_10_1080_15622975_2016_1224929 crossref_primary_10_1097_MCO_0000000000000353 crossref_primary_10_14814_phy2_14108 crossref_primary_10_1182_blood_2018886317 crossref_primary_10_3390_antiox11040611 crossref_primary_10_1016_j_gene_2015_07_073 crossref_primary_10_1016_j_pharmthera_2020_107670 crossref_primary_10_3390_molecules30102212 |
| Cites_doi | 10.1096/fj.10-178657 10.1523/JNEUROSCI.2443-11.2011 10.1096/fj.13-227728 10.1016/S0165-6147(03)00166-4 10.1038/nature05877 10.4049/jimmunol.0900327 10.1007/s11745-005-1379-z 10.1038/nature08541 10.1161/01.CIR.99.18.2452 10.1074/jbc.M300218200 10.1152/ajprenal.00224.2003 10.1073/pnas.92.21.9475 10.1038/nature01320 10.2353/ajpath.2010.100322 10.1016/j.it.2011.05.001 10.3760/cma.j.issn.0366-6999.20131104 10.1038/9550 10.1096/fj.10-161836 10.1161/01.STR.0000149620.74770.2e 10.1152/ajpgi.00106.2013 10.1074/jbc.M109.003822 10.4049/jimmunol.0900477 10.1084/jem.20081880 10.1016/0006-291X(84)90601-6 10.1038/nature01325 10.1016/j.jaci.2012.07.048 10.1074/jbc.275.9.6586 10.1016/j.clim.2007.08.012 10.1172/JCI42545 10.1194/jlr.M000059 10.1038/nm.3549 10.1016/0005-2760(89)90264-6 10.4049/jimmunol.177.9.5902 10.1074/jbc.M109.095232 10.1074/jbc.M509796200 10.1126/science.2820055 10.1073/pnas.76.5.2148 10.1074/jbc.X112.351437 10.1007/s00418-004-0695-8 10.1021/bi00076a002 10.1084/jem.183.1.137 10.4049/jimmunol.1202743 10.1016/j.tetlet.2012.01.032 10.1016/j.febslet.2009.10.004 10.1074/jbc.M410638200 10.1016/j.chembiol.2011.06.008 10.1038/nchembio.364 10.1016/j.prostaglandins.2005.04.004 10.1016/S0021-9258(18)66571-8 10.1096/fj.06-6250fje 10.1182/blood-2012-04-423525 10.1194/jlr.R001131 10.1172/JCI59643 10.1016/j.plefa.2009.10.010 10.1073/pnas.0405445101 10.1084/jem.154.4.1243 10.1038/ni1276 10.1073/pnas.0402531101 10.1371/journal.pone.0073085 10.1161/RES.0b013e31825ec26d 10.1016/j.cell.2013.02.027 10.5414/CPP42672 10.1023/B:MCBI.0000041863.11248.8d 10.1146/annurev.pharmtox.011008.145616 10.1007/s11745-001-0805-6 10.1084/jem.192.8.1197 10.1038/nm1591 10.1073/pnas.81.3.689 10.1016/j.expneurol.2012.04.007 10.1096/fj.08-112201 10.1074/jbc.M109.003988 10.1161/01.CIR.0000014682.14181.F2 10.1038/nature11042 10.1167/iovs.09-3641 10.1167/iovs.13-12152 10.3945/ajcn.110.003871 10.1007/s12035-011-8174-4 10.1021/cr100396c 10.1074/jbc.M609212200 10.1186/1465-9921-14-51 10.1038/nature01323 10.1016/0005-2760(94)90185-6 10.1016/j.bbalip.2012.07.011 10.1089/scd.2011.0220 10.1016/j.prostaglandins.2004.03.005 10.4049/jimmunol.176.3.1848 10.1074/jbc.M110.100388 10.4049/jimmunol.178.1.496 10.1016/j.plefa.2008.09.022 10.1096/fj.06-7918com 10.1016/j.plefa.2012.08.005 10.1074/jbc.M305841200 10.1146/annurev-nutr-071811-150726 10.4049/jimmunol.164.4.1663 10.1371/journal.pone.0102362 10.1038/srep01940 10.1902/jop.2010.090628 10.1146/annurev.immunol.25.022106.141647 10.1016/S0022-3565(25)12050-8 10.1016/S0021-9258(20)78281-5 10.1073/pnas.92.18.8383 10.1126/science.6301011 10.4049/jimmunol.173.2.1284 10.1074/jbc.M106577200 10.1038/nature01322 10.4049/jimmunol.174.7.4345 10.1016/j.coph.2013.05.012 10.1002/ana.23928 10.1016/S0021-9258(18)34537-X 10.1096/fj.11-201442 10.4049/jimmunol.0802064 10.1016/j.immuni.2013.10.011 10.3389/fimmu.2012.00004 10.1523/JNEUROSCI.4225-04.2005 10.1126/science.1230720 10.1016/S0140-6736(10)61543-7 10.1096/fj.08-125674 10.4049/jimmunol.0903816 10.1182/blood-2011-04-345330 10.1073/pnas.0601280103 10.1167/iovs.13-12075 10.1016/j.tins.2006.03.005 10.1093/jn/135.4.687 10.1084/jem.20020760 10.1046/j.1471-4159.1994.62062437.x 10.4049/jimmunol.171.12.6856 10.1038/nrd1383 10.4049/jimmunol.1100225 10.1038/89759 10.4049/jimmunol.1202969 10.1172/JCI25420 10.1096/fj.10-170027 10.1111/j.1528-1167.2011.03081.x 10.1136/annrheumdis-2011-200745 10.1038/ni1392 10.1016/j.cell.2010.02.043 10.2353/ajpath.2010.090678 10.1016/j.coph.2005.02.006 10.1016/S0889-857X(03)00117-0 |
| ContentType | Journal Article |
| Copyright | 2014 Elsevier B.V. Copyright © 2014 Elsevier B.V. All rights reserved. |
| Copyright_xml | – notice: 2014 Elsevier B.V. – notice: Copyright © 2014 Elsevier B.V. All rights reserved. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7S9 L.6 |
| DOI | 10.1016/j.bbalip.2014.08.006 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic AGRICOLA AGRICOLA - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE AGRICOLA |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: 7X8 name: MEDLINE - Academic url: https://search.proquest.com/medline sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology Chemistry Biology |
| EISSN | 1879-2618 |
| EndPage | 413 |
| ExternalDocumentID | 25139562 10_1016_j_bbalip_2014_08_006 S1388198114001619 |
| Genre | Review Research Support, Non-U.S. Gov't Journal Article Research Support, N.I.H., Extramural |
| GrantInformation_xml | – fundername: NIGMS NIH HHS grantid: P01 GM095467 – fundername: NIGMS NIH HHS grantid: R01 GM038765 – fundername: NIGMS NIH HHS grantid: R01GM038765 – fundername: NIGMS NIH HHS grantid: P01GM095467 |
| GroupedDBID | --- --K --M .~1 0R~ 1B1 1RT 1~. 1~5 23N 3O- 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ AACTN AAEDT AAEDW AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXUO ABEFU ABFNM ABGSF ABMAC ABUDA ABXDB ABYKQ ACDAQ ACIUM ACRLP ADBBV ADEZE ADMUD ADUVX AEBSH AEHWI AEKER AFKWA AFTJW AFXIZ AGHFR AGRDE AGUBO AGYEJ AIEXJ AIKHN AITUG AJBFU AJOXV ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC CS3 DOVZS EBS EFJIC EFLBG EJD EO8 EO9 EP2 EP3 FDB FEDTE FGOYB FIRID FNPLU FYGXN G-Q GBLVA HVGLF HZ~ IHE J1W KOM M41 MO0 N9A O-L O9- OAUVE OZT P-8 P-9 PC. Q38 R2- ROL RPZ SDF SDG SDP SES SEW SSU SSZ T5K XJT XPP ~G- 9DU AAHBH AATTM AAXKI AAYWO AAYXX ABWVN ACLOT ACRPL ADNMO AEIPS AFJKZ AGQPQ AIIUN ANKPU CITATION EFKBS ~HD -~X .55 .GJ 5RE AAYJJ ABJNI AFFNX AHHHB AI. AKRWK CGR CUY CVF ECM EIF F5P G-2 HLW H~9 K-O LX3 MVM NPM OHT RIG SBG TWZ UHS VH1 WH7 WUQ X7M Y6R YYP ZE2 ZGI ~KM 7X8 7S9 L.6 |
| ID | FETCH-LOGICAL-c632t-673cfc963ece33cc3d9e6cc6f9e0453972b8d38b173ffaa0c89c8292a4f89d2a3 |
| ISICitedReferencesCount | 396 |
| ISICitedReferencesURI | http://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=Summon&SrcAuth=ProQuest&DestLinkType=CitingArticles&DestApp=WOS_CPL&KeyUT=000350186800009&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| ISSN | 1388-1981 0006-3002 |
| IngestDate | Sun Sep 28 01:44:58 EDT 2025 Fri Sep 05 10:36:20 EDT 2025 Mon Jul 21 05:55:46 EDT 2025 Sat Nov 29 08:00:48 EST 2025 Tue Nov 18 22:41:07 EST 2025 Fri Feb 23 02:11:12 EST 2024 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 4 |
| Keywords | Resolvin LC–MS–MS-based targeted lipid mediator metabolomics Leukocyte Lipid mediator Eicosanoid |
| Language | English |
| License | Copyright © 2014 Elsevier B.V. All rights reserved. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c632t-673cfc963ece33cc3d9e6cc6f9e0453972b8d38b173ffaa0c89c8292a4f89d2a3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 ObjectType-Review-3 content type line 23 |
| OpenAccessLink | http://doi.org/10.1016/j.bbalip.2014.08.006 |
| PMID | 25139562 |
| PQID | 1706207066 |
| PQPubID | 23479 |
| PageCount | 17 |
| ParticipantIDs | proquest_miscellaneous_2000330046 proquest_miscellaneous_1706207066 pubmed_primary_25139562 crossref_citationtrail_10_1016_j_bbalip_2014_08_006 crossref_primary_10_1016_j_bbalip_2014_08_006 elsevier_sciencedirect_doi_10_1016_j_bbalip_2014_08_006 |
| PublicationCentury | 2000 |
| PublicationDate | 2015-04-01 |
| PublicationDateYYYYMMDD | 2015-04-01 |
| PublicationDate_xml | – month: 04 year: 2015 text: 2015-04-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Netherlands |
| PublicationPlace_xml | – name: Netherlands |
| PublicationTitle | Biochimica et biophysica acta |
| PublicationTitleAlternate | Biochim Biophys Acta |
| PublicationYear | 2015 |
| Publisher | Elsevier B.V |
| Publisher_xml | – name: Elsevier B.V |
| References | Li, Dalli, Chiang, Baron, Quintana, Serhan (bb0785) 2013; 39 Vane (bb0440) 1982 Leedom, Sullivan, Dong, Lau, Gronert (bb0810) 2010; 176 Van Dyke, Serhan (bb0535) 2006 White, St-Pierre, Charbonneau, Mitchell, St-Amand, Marcotte, Marette (bb0335) 2014; 20 Chan, Moore (bb0805) 2010; 184 Serhan (bb0330) 1989; 1004 Antoni, Braun (bb0500) 2002; 20 Serhan, Clish, Brannon, Colgan, Chiang, Gronert (bb0050) 2000; 192 Levy, Kohli, Gotlinger, Haworth, Hong, Kazani, Israel, Haley, Serhan (bb0685) 2007; 178 Gordon (bb0260) 2012; 110 González-Périz, Horrillo, Ferré, Gronert, Dong, Morán-Salvador, Titos, Martínez-Clemente, López-Parra, Arroyo, Clària (bb0735) 2009; 23 Morris, Stables, Hobbs, de Souza, Colville-Nash, Warner, Newson, Bellingan, Gilroy (bb0460) 2009; 183 Zhang, Spite (bb0550) 2012; 32 Serhan, Fiore, Brezinski, Lynch (bb0455) 1993; 32 González-Périz, Planagumà, Gronert, Miquel, López-Parra, Titos, Horrillo, Ferré, Deulofeu, Arroyo, Rodés, Clària (bb0715) 2006; 20 Yanes, Clark, Wong, Patti, Sánchez-Ruiz, Benton, Trauger, Desponts, Ding, Siuzdak (bb0375) 2010; 6 Oh, Pillai, Recchiuti, Yang, Serhan (bb0640) 2011; 121 Biteman, Hassan, Walker, Leedom, Dunn, Seta, Laniado-Schwartzman, Gronert (bb0795) 2007; 21 Morita, Kuba, Ichikawa, Nakayama, Katahira, Iwamoto, Watanebe, Sakabe, Daidoji, Nakamura, Kadowaki, Ohto, Nakanishi, Taguchi, Nakaya, Murakami, Yoneda, Arai, Kawaoka, Penninger, Arita, Imai (bb0765) 2013; 153 Kuhn, Brash, Wiesner, Alder (bb0310) 1988; 229 Tian, Lu, Shah, Hong (bb0610) 2011; 286 Samuelsson (bb0055) 1983; 220 Sica, Mantovani (bb0255) 2012; 122 Tian, Lu, Shah, Wang, Hong (bb0605) 2012; 21 Titos, Rius, Gonzalez-Periz, Lopez-Vicario, Moran-Salvador, Martinez-Clemente, Arroyo, Claria (bb0595) 2011; 187 Weiner, Selkoe (bb0090) 2002; 420 Gronert, Maheshwari, Khan, Hassan, Dunn, Schwartzman (bb0230) 2005; 280 Whelan (bb0395) 1988 Borgeat, Samuelsson (bb0485) 1979; 76 Calandria, Marcheselli, Mukherjee, Uddin, Winkler, Petasis, Bazan (bb0675) 2009; 284 Samuelsson (bb0095) 2012; 287 Nordgren, Heires, Wyatt, Poole, Levan, Cerutis, Romberger (bb0790) 2013; 14 Sun, Oh, Uddin, Yang, Gotlinger, Campbell, Colgan, Petasis, Serhan (bb0470) 2007; 282 Schwab, Chiang, Arita, Serhan (bb0380) 2007; 447 Yamada, Tani, Nakanishi, Taguchi, Arita, Arai (bb0700) 2011; 25 Belayev, Marcheselli, Khoutorova, Rodriguez de Turco, Busto, Ginsberg, Bazan (bb0225) 2005; 36 Serhan, Savill (bb0040) 2005; 6 Gilroy, Perretti (bb0425) 2005; 5 Lukiw, Cui, Marcheselli, Bodker, Botkjaer, Gotlinger, Serhan, Bazan (bb0710) 2005; 115 Bazan, Birkle, Reddy (bb0205) 1984; 125 Ariel, Li, Wang, Tang, Fredman, Hong, Gotlinger, Serhan (bb0240) 2005; 280 Burr, Burr (bb0165) 1929; 82 Sawazaki, Salem, Kim (bb0210) 1994; 62 Chen, Fenet, Michaud, Tomczyk, Véricel, Lagarde, Guichardant (bb0320) 2009; 583 Stables, Shah, Camon, Lovering, Newson, Bystrom, Farrow, Gilroy (bb0545) 2011; 118 Miyata, Fukunaga, Iwamoto, Isobe, Niimi, Takamiya, Takihara, Tomomatsu, Suzuki, Oguma, Sayama, Arai, Betsuyaku, Arita, Asano (bb0695) 2013; 131 Musto, Gjorstrup, Bazan (bb0750) 2011; 52 Duffield, Hong, Vaidya, Lu, Fredman, Serhan, Bonventre (bb0705) 2006; 177 Godson, Mitchell, Harvey, Petasis, Hogg, Brady (bb0135) 2000; 164 Marcheselli, Hong, Lukiw, Hua Tian, Gronert, Musto, Hardy, Gimenez, Chiang, Serhan, Bazan (bb0220) 2003; 278 Marcheselli, Mukherjee, Arita, Hong, Antony, Sheets, Petasis, Serhan, Bazan (bb0385) 2010; 82 Serhan (bb0125) 1994; 1212 Samuelsson, Dahlén, Lindgren, Rouzer, Serhan (bb0115) 1987; 237 Maddox, Serhan (bb0140) 1996; 183 Hong, Tjonahen, Morgan, Yu, Serhan, Rowley (bb0235) 2005; 78 Serhan, Chiang (bb0105) 2004; 30 Serhan, Jain, Marleau, Clish, Kantarci, Behbehani, Colgan, Stahl, Merched, Petasis, Chan, Van Dyke (bb0660) 2003; 171 Hassan, Gronert (bb0365) 2009; 182 Antony, Lukiw, Bazan (bb0760) 2010; 285 Park, Lü, Xu, Liu, Serhan, Ji (bb0350) 2011; 31 Merched, Ko, Gotlinger, Serhan, Chan (bb0665) 2008; 22 El-Sharkawy, Aboelsaad, Eliwa, Darweesh, Alshahat, Kantarci, Hasturk, Van Dyke (bb0530) 2010; 81 Xu, Liu, Berta, Park, Lu, Serhan, Ji (bb0740) 2013; 74 Bazan (bb0005) 2006; 29 Bazan, Calandria, Serhan (bb0060) 2010; 51 Yanes, Clark, Wong, Patti, Sanchez-Ruiz, Benton, Trauger, Desponts, Ding, Siuzdak (bb0650) 2010; 6 Gilroy, Lawrence, Perretti, Rossi (bb0145) 2004; 3 Giera, Ioan-Facsinay, Toes, Gao, Dalli, Deelder, Serhan, Mayboroda (bb0565) 2012; 1821 Skulas-Ray, Kris-Etherton, Harris, Vanden Heuvel, Wagner, West (bb0525) 2011; 93 Samuelsson (bb0435) 1982 Serhan, Petasis (bb0480) 2011; 111 Chiang, Fredman, Bäckhed, Oh, Vickery, Schmidt, Serhan (bb0285) 2012; 484 Wetterholm, Haeggström, Samuelsson, Yuan, Munoz, Wong (bb0515) 1995; 275 Cortina, He, Russ, Bazan, Bazan (bb0720) 2013; 54 Chiang, Fredman, Backhed, Oh, Vickery, Schmidt, Serhan (bb0630) 2012; 484 Serhan, Yang, Martinod, Kasuga, Pillai, Porter, Oh, Spite (bb0275) 2009; 206 Maas, Turk, Oates, Brash (bb0325) 1982; 257 Chen, Vericel, Lagarde, Guichardant (bb0680) 2011; 25 Serhan, Chiang (bb0390) 2013; 13 Clària, Serhan (bb0430) 1995; 92 Koltsida, Karamnov, Pyrillou, Vickery, Chairakaki, Tamvakopoulos, Sideras, Serhan, Andreakos (bb0690) 2013; 5 Serhan (bb0025) 2010; 177 Bazan (bb0200) 1990; vol. 8 Serhan, Gotlinger, Hong, Arita (bb0155) 2004; 73 Bannenberg, Chiang, Ariel, Arita, Tjonahen, Gotlinger, Hong, Serhan (bb0215) 2005; 174 Serhan, Dalli, Karamnov, Choi, Park, Xu, Ji, Zhu, Petasis (bb0270) 2012; 26 Serhan, Gotlinger, Hong, Lu, Siegelman, Baer, Yang, Colgan, Petasis (bb0250) 2006; 176 Li, Li, Liang, Bi, Chen, Dong (bb0770) 2014; 127 Bazan, Eady, Khoutorova, Atkins, Hong, Lu, Zhang, Jun, Obenaus, Fredman, Zhu, Winkler, Petasis, Serhan, Belayev (bb0775) 2012; 236 Dalli, Serhan (bb0560) 2012; 120 Lu, Tian, Hong (bb0600) 2010; 51 Rudberg, Tholander, Thunnissen, Haeggström (bb0635) 2002; 277 Serhan, Hong, Gronert, Colgan, Devchand, Mirick, Moussignac (bb0045) 2002; 196 Hong, Gronert, Devchand, Moussignac, Serhan (bb0065) 2003; 278 Deng, Wang, Arnardottir, Li, Cheng, Dalli, Serhan (bb0580) 2014; 9 Chiang, Shinohara, Dalli, Mirakaj, Kibi, Choi, Serhan (bb0670) 2013; 190 Chiang, Bermudez, Ridker, Hurwitz, Serhan (bb0450) 2004; 101 Billman, Kang, Leaf (bb0175) 1999; 99 Shimizu, Rådmark, Samuelsson (bb0510) 1984; 81 Mueller, Wetterholm, Blomster, Jornvall, Samuelsson, Haeggstrom (bb0655) 1995; 92 Kronke, Katzenbeisser, Uderhardt, Zaiss, Scholtysek, Schabbauer, Zarbock, Koenders, Axmann, Zwerina, Baenckler, van den Berg, Voll, Kuhn, Joosten, Schett (bb0800) 2009; 183 Stables, Shah, Camon, Lovering, Newson, Bystrom, Farrow, Gilroy (bb0265) 2011; 118 Lewis, Goetzl, Drazen, Soter, Austen, Corey (bb0495) 1981; 154 Blaho, Buczynski, Brown, Dennis (bb0725) 2009; 284 Marcon, Bento, Dutra, Bicca, Leite, Calixto (bb0780) 2013; 191 Carey, Sundberg (bb0490) 2007 McMahon, Godson (bb0120) 2004; 286 Serhan, Dalli, Karamnov, Choi, Park, Xu, Ji, Zhu, Petasis (bb0570) 2012; 26 Yang (bb0290) 2005 Petasis, Yang, Winkler, Zhu, Uddin, Bazan, Serhan (bb0295) 2012; 53 Dalli, Zhu, Vlasenko, Deng, Haeggstrom, Petasis, Serhan (bb0575) 2013; 27 Serhan, Nicolaou, Webber, Veale, Dahlen, Puustinen, Samuelsson (bb0305) 1986; 261 Majno, Joris (bb0075) 2004 Dalli, Colas, Serhan (bb0160) 2013; 3 Crawford, Broadhurst, Guest, Nagar, Wang, Ghebremeskel, Schmidt (bb0010) 2013; 88 Serhan (bb0150) 2004; 122 Kalish, Le, Fitzgerald, Wang, Seamon, Gura, Gronert, Puder (bb0410) 2013; 305 Camuesco, Galvez, Nieto, Comalada, Rodriguez-Cabezas, Concha, Xaus, Zarzuelo (bb0170) 2005; 135 Engler, Engler, Malloy, Chiu, Besio, Paul, Stuehlinger, Morrow, Ridker, Rifai, Mietus-Snyder (bb0190) 2004; 42 Ariel, Fredman, Sun, Kantarci, Van Dyke, Luster, Serhan (bb0345) 2006; 7 Nathan (bb0100) 2002; 420 Ariel, Serhan (bb0540) 2012; 3 Marchioli, Barzi, Bomba, Chieffo, Di Gregorio, Di Mascio, Franzosi, Geraci, Levantesi, Maggioni, Mantini, Marfisi, Mastrogiuseppe, Mininni, Nicolosi, Santini, Schweiger, Tavazzi, Tognoni, Tucci, Valagussa (bb0180) 2002; 105 Gronert, Clish, Romano, Serhan (bb0315) 1999 Ingersoll, Platt, Potteaux, Randolph (bb0585) 2011; 32 Levy, Clish, Schmidt, Gronert, Serhan (bb0110) 2001; 2 Shimizu (bb0620) 2009; 49 Majno, Cotran, Kaufman (bb0030) 1982; vol. 23 C.N. Serhan, Resolvins: biotemplates for novel therapeutic interventions, in: U.S. Patent 7,585,856 and Application Publication 2004/0116408 A1, Brigham and Women's Hospital, 2004. Serhan, Fredman, Yang, Karamnov, Belayev, Bazan, Zhu, Winkler, Petasis (bb0245) 2011; 18 Coussens, Werb (bb0080) 2002; 420 Serhan, Samuelsson (bb0300) 1988; 229 Rajasagi, Reddy, Mulik, Gjorstrup, Rouse (bb0745) 2013; 54 Hellmann, Tang, Kosuri, Bhatnagar, Spite (bb0590) 2011; 25 Mukherjee, Marcheselli, Serhan, Bazan (bb0070) 2004; 101 Tomio, Kawana, Taguchi, Isobe, Iwamoto, Yamashita, Kojima, Mori, Nagamatsu, Arimoto, Oda, Osuga, Taketani, Kang, Arai, Arita, Kozuma, Fujii (bb0820) 2013; 8 Rowlinson, Crews, Goodwin, Schneider, Gierse, Marnett (bb0445) 2000 Samuelsson (bb0615) 2012; 287 Lands (bb0015) 2005 Whelan, Reddanna, Nikolaev, Hildenbrandt, Reddy (bb0400) 1990; vol. 2 Tsikitis, Morin, Harrington, Albina, Reichner (bb0465) 2004; 173 Salem, Litman, Kim, Gawrisch (bb0020) 2001; 36 Lin, Ziring, Desai, Kim, Wong, Korin, Braun, Reed, Gjertson, Singh (bb0505) 2008; 126 Spite, Norling, Summers, Yang, Cooper, Petasis, Flower, Perretti, Serhan (bb0625) 2009; 461 Kronke, Reich, Scholtysek, Akhmetshina, Uderhardt, Zerr, Palumbo, Lang, Dees, Distler, Schett, Distler (bb0815) 2012; 71 Lim, Calon, Morihara, Yang, Teter, Ubeda, Salem, Frautschy, Cole (bb0195) 2005; 25 Hudert, Weylandt, Wang, Lu, Hong, Dignass, Serhan, Kang (bb0755) 2006; 103 Stark, Bazan (bb0360) 2011; 43 Gilroy, Colville-Nash, Willis, Chivers, Paul-Clark, Willoughby (bb0415) 1999; 5 Libby (bb0085) 2002; 420 Qin, Patil, Gronert, Sharma (bb0730) 2008; 79 Rothwell, Wilson, Elwin, Norrving, Algra, Warlow, Meade (bb0520) 2010; 376 Spite, Norling, Summers, Yang, Cooper, Petasis, Flower, Perretti, Serhan (bb0475) 2009; 461 Tabas, Glass (bb0340) 2013; 339 Holub, Holub (bb0185) 2004; 263 Dinarello (bb0035) 2010; 140 Butovich, Hamberg, Rådmark (bb0405) 2005; 40 Serhan (bb0420) 2007; 25 Serhan, Yang, Martinod, Kasuga, Pilla Sica (10.1016/j.bbalip.2014.08.006_bb0255) 2012; 122 Chan (10.1016/j.bbalip.2014.08.006_bb0805) 2010; 184 Kuhn (10.1016/j.bbalip.2014.08.006_bb0310) 1988; 229 Merched (10.1016/j.bbalip.2014.08.006_bb0665) 2008; 22 Lewis (10.1016/j.bbalip.2014.08.006_bb0495) 1981; 154 Stables (10.1016/j.bbalip.2014.08.006_bb0545) 2011; 118 Dalli (10.1016/j.bbalip.2014.08.006_bb0575) 2013; 27 Libby (10.1016/j.bbalip.2014.08.006_bb0085) 2002; 420 Spite (10.1016/j.bbalip.2014.08.006_bb0475) 2009; 461 Chiang (10.1016/j.bbalip.2014.08.006_bb0670) 2013; 190 Giera (10.1016/j.bbalip.2014.08.006_bb0565) 2012; 1821 Serhan (10.1016/j.bbalip.2014.08.006_bb0305) 1986; 261 Majno (10.1016/j.bbalip.2014.08.006_bb0075) 2004 Bazan (10.1016/j.bbalip.2014.08.006_bb0200) 1990; vol. 8 Billman (10.1016/j.bbalip.2014.08.006_bb0175) 1999; 99 Hellmann (10.1016/j.bbalip.2014.08.006_bb0590) 2011; 25 Chiang (10.1016/j.bbalip.2014.08.006_bb0450) 2004; 101 Ingersoll (10.1016/j.bbalip.2014.08.006_bb0585) 2011; 32 Serhan (10.1016/j.bbalip.2014.08.006_bb0390) 2013; 13 Whelan (10.1016/j.bbalip.2014.08.006_bb0395) 1988 Titos (10.1016/j.bbalip.2014.08.006_bb0595) 2011; 187 Clària (10.1016/j.bbalip.2014.08.006_bb0430) 1995; 92 Samuelsson (10.1016/j.bbalip.2014.08.006_bb0615) 2012; 287 Sun (10.1016/j.bbalip.2014.08.006_bb0470) 2007; 282 Hong (10.1016/j.bbalip.2014.08.006_bb0235) 2005; 78 Vane (10.1016/j.bbalip.2014.08.006_bb0440) 1982 Belayev (10.1016/j.bbalip.2014.08.006_bb0225) 2005; 36 Levy (10.1016/j.bbalip.2014.08.006_bb0110) 2001; 2 Serhan (10.1016/j.bbalip.2014.08.006_bb0275) 2009; 206 Oh (10.1016/j.bbalip.2014.08.006_bb0640) 2011; 121 Serhan (10.1016/j.bbalip.2014.08.006_bb0245) 2011; 18 Morita (10.1016/j.bbalip.2014.08.006_bb0765) 2013; 153 Kronke (10.1016/j.bbalip.2014.08.006_bb0800) 2009; 183 Bannenberg (10.1016/j.bbalip.2014.08.006_bb0215) 2005; 174 Serhan (10.1016/j.bbalip.2014.08.006_bb0150) 2004; 122 Serhan (10.1016/j.bbalip.2014.08.006_bb0155) 2004; 73 Serhan (10.1016/j.bbalip.2014.08.006_bb0040) 2005; 6 Lukiw (10.1016/j.bbalip.2014.08.006_bb0710) 2005; 115 Wallace (10.1016/j.bbalip.2014.08.006_bb0130) 2003; 24 Rudberg (10.1016/j.bbalip.2014.08.006_bb0635) 2002; 277 Chen (10.1016/j.bbalip.2014.08.006_bb0680) 2011; 25 Nathan (10.1016/j.bbalip.2014.08.006_bb0100) 2002; 420 Leedom (10.1016/j.bbalip.2014.08.006_bb0810) 2010; 176 Gronert (10.1016/j.bbalip.2014.08.006_bb0230) 2005; 280 Hudert (10.1016/j.bbalip.2014.08.006_bb0755) 2006; 103 Serhan (10.1016/j.bbalip.2014.08.006_bb0125) 1994; 1212 Van Dyke (10.1016/j.bbalip.2014.08.006_bb0535) 2006 Tian (10.1016/j.bbalip.2014.08.006_bb0605) 2012; 21 Rothwell (10.1016/j.bbalip.2014.08.006_bb0520) 2010; 376 Levy (10.1016/j.bbalip.2014.08.006_bb0685) 2007; 178 Butovich (10.1016/j.bbalip.2014.08.006_bb0405) 2005; 40 Whelan (10.1016/j.bbalip.2014.08.006_bb0400) 1990; vol. 2 Connor (10.1016/j.bbalip.2014.08.006_bb0355) 2007; 13 Shimizu (10.1016/j.bbalip.2014.08.006_bb0510) 1984; 81 Antoni (10.1016/j.bbalip.2014.08.006_bb0500) 2002; 20 Serhan (10.1016/j.bbalip.2014.08.006_bb0645) 2010 Samuelsson (10.1016/j.bbalip.2014.08.006_bb0055) 1983; 220 Xu (10.1016/j.bbalip.2014.08.006_bb0740) 2013; 74 Samuelsson (10.1016/j.bbalip.2014.08.006_bb0115) 1987; 237 Salem (10.1016/j.bbalip.2014.08.006_bb0020) 2001; 36 Serhan (10.1016/j.bbalip.2014.08.006_bb0025) 2010; 177 Yanes (10.1016/j.bbalip.2014.08.006_bb0650) 2010; 6 Tomio (10.1016/j.bbalip.2014.08.006_bb0820) 2013; 8 Godson (10.1016/j.bbalip.2014.08.006_bb0135) 2000; 164 Samuelsson (10.1016/j.bbalip.2014.08.006_bb0435) 1982 Dalli (10.1016/j.bbalip.2014.08.006_bb0560) 2012; 120 Kronke (10.1016/j.bbalip.2014.08.006_bb0815) 2012; 71 Bazan (10.1016/j.bbalip.2014.08.006_bb0775) 2012; 236 Yamada (10.1016/j.bbalip.2014.08.006_bb0700) 2011; 25 Cortina (10.1016/j.bbalip.2014.08.006_bb0720) 2013; 54 Lin (10.1016/j.bbalip.2014.08.006_bb0505) 2008; 126 Serhan (10.1016/j.bbalip.2014.08.006_bb0105) 2004; 30 Tian (10.1016/j.bbalip.2014.08.006_bb0610) 2011; 286 Shimizu (10.1016/j.bbalip.2014.08.006_bb0620) 2009; 49 Duffield (10.1016/j.bbalip.2014.08.006_bb0705) 2006; 177 Burr (10.1016/j.bbalip.2014.08.006_bb0165) 1929; 82 Petasis (10.1016/j.bbalip.2014.08.006_bb0295) 2012; 53 Hassan (10.1016/j.bbalip.2014.08.006_bb0365) 2009; 182 Crawford (10.1016/j.bbalip.2014.08.006_bb0010) 2013; 88 Weiner (10.1016/j.bbalip.2014.08.006_bb0090) 2002; 420 Gordon (10.1016/j.bbalip.2014.08.006_bb0260) 2012; 110 Chiang (10.1016/j.bbalip.2014.08.006_bb0285) 2012; 484 Zhang (10.1016/j.bbalip.2014.08.006_bb0550) 2012; 32 Lim (10.1016/j.bbalip.2014.08.006_bb0195) 2005; 25 Bazan (10.1016/j.bbalip.2014.08.006_bb0060) 2010; 51 Gilroy (10.1016/j.bbalip.2014.08.006_bb0415) 1999; 5 González-Périz (10.1016/j.bbalip.2014.08.006_bb0715) 2006; 20 Spite (10.1016/j.bbalip.2014.08.006_bb0625) 2009; 461 Rowlinson (10.1016/j.bbalip.2014.08.006_bb0445) 2000 Mukherjee (10.1016/j.bbalip.2014.08.006_bb0070) 2004; 101 Majno (10.1016/j.bbalip.2014.08.006_bb0030) 1982; vol. 23 Serhan (10.1016/j.bbalip.2014.08.006_bb0330) 1989; 1004 Gilroy (10.1016/j.bbalip.2014.08.006_bb0145) 2004; 3 Antony (10.1016/j.bbalip.2014.08.006_bb0760) 2010; 285 Serhan (10.1016/j.bbalip.2014.08.006_bb0455) 1993; 32 Schwab (10.1016/j.bbalip.2014.08.006_bb0380) 2007; 447 Samuelsson (10.1016/j.bbalip.2014.08.006_bb0095) 2012; 287 Maddox (10.1016/j.bbalip.2014.08.006_bb0140) 1996; 183 Koltsida (10.1016/j.bbalip.2014.08.006_bb0690) 2013; 5 Yang (10.1016/j.bbalip.2014.08.006_bb0290) 2005 Miyata (10.1016/j.bbalip.2014.08.006_bb0695) 2013; 131 Qin (10.1016/j.bbalip.2014.08.006_bb0730) 2008; 79 Camuesco (10.1016/j.bbalip.2014.08.006_bb0170) 2005; 135 Ariel (10.1016/j.bbalip.2014.08.006_bb0345) 2006; 7 Serhan (10.1016/j.bbalip.2014.08.006_bb0570) 2012; 26 Serhan (10.1016/j.bbalip.2014.08.006_bb0045) 2002; 196 Sawazaki (10.1016/j.bbalip.2014.08.006_bb0210) 1994; 62 Serhan (10.1016/j.bbalip.2014.08.006_bb0555) 2009; 206 Serhan (10.1016/j.bbalip.2014.08.006_bb0480) 2011; 111 González-Périz (10.1016/j.bbalip.2014.08.006_bb0735) 2009; 23 Serhan (10.1016/j.bbalip.2014.08.006_bb0050) 2000; 192 Lu (10.1016/j.bbalip.2014.08.006_bb0600) 2010; 51 Tsikitis (10.1016/j.bbalip.2014.08.006_bb0465) 2004; 173 Engler (10.1016/j.bbalip.2014.08.006_bb0190) 2004; 42 Calandria (10.1016/j.bbalip.2014.08.006_bb0675) 2009; 284 Serhan (10.1016/j.bbalip.2014.08.006_bb0270) 2012; 26 Yanes (10.1016/j.bbalip.2014.08.006_bb0375) 2010; 6 Carey (10.1016/j.bbalip.2014.08.006_bb0490) 2007 Marchioli (10.1016/j.bbalip.2014.08.006_bb0180) 2002; 105 Bazan (10.1016/j.bbalip.2014.08.006_bb0205) 1984; 125 Hong (10.1016/j.bbalip.2014.08.006_bb0065) 2003; 278 Holub (10.1016/j.bbalip.2014.08.006_bb0185) 2004; 263 Stables (10.1016/j.bbalip.2014.08.006_bb0265) 2011; 118 White (10.1016/j.bbalip.2014.08.006_bb0335) 2014; 20 Morris (10.1016/j.bbalip.2014.08.006_bb0460) 2009; 183 Kalish (10.1016/j.bbalip.2014.08.006_bb0410) 2013; 305 Li (10.1016/j.bbalip.2014.08.006_bb0770) 2014; 127 Li (10.1016/j.bbalip.2014.08.006_bb0785) 2013; 39 Gilroy (10.1016/j.bbalip.2014.08.006_bb0425) 2005; 5 McMahon (10.1016/j.bbalip.2014.08.006_bb0120) 2004; 286 Maas (10.1016/j.bbalip.2014.08.006_bb0325) 1982; 257 Wetterholm (10.1016/j.bbalip.2014.08.006_bb0515) 1995; 275 Rajasagi (10.1016/j.bbalip.2014.08.006_bb0745) 2013; 54 Park (10.1016/j.bbalip.2014.08.006_bb0350) 2011; 31 Biteman (10.1016/j.bbalip.2014.08.006_bb0795) 2007; 21 Mueller (10.1016/j.bbalip.2014.08.006_bb0655) 1995; 92 Deng (10.1016/j.bbalip.2014.08.006_bb0580) 2014; 9 Blaho (10.1016/j.bbalip.2014.08.006_bb0725) 2009; 284 Lands (10.1016/j.bbalip.2014.08.006_bb0015) 2005 10.1016/j.bbalip.2014.08.006_bb0280 Gronert (10.1016/j.bbalip.2014.08.006_bb0315) 1999 Serhan (10.1016/j.bbalip.2014.08.006_bb0250) 2006; 176 Serhan (10.1016/j.bbalip.2014.08.006_bb0660) 2003; 171 Marcon (10.1016/j.bbalip.2014.08.006_bb0780) 2013; 191 Dinarello (10.1016/j.bbalip.2014.08.006_bb0035) 2010; 140 Dalli (10.1016/j.bbalip.2014.08.006_bb0160) 2013; 3 Bazan (10.1016/j.bbalip.2014.08.006_bb0005) 2006; 29 Serhan (10.1016/j.bbalip.2014.08.006_bb0420) 2007; 25 Musto (10.1016/j.bbalip.2014.08.006_bb0750) 2011; 52 El-Sharkawy (10.1016/j.bbalip.2014.08.006_bb0530) 2010; 81 Chiang (10.1016/j.bbalip.2014.08.006_bb0630) 2012; 484 Chen (10.1016/j.bbalip.2014.08.006_bb0320) 2009; 583 Serhan (10.1016/j.bbalip.2014.08.006_bb0300) 1988; 229 Marcheselli (10.1016/j.bbalip.2014.08.006_bb0385) 2010; 82 Stark (10.1016/j.bbalip.2014.08.006_bb0360) 2011; 43 Nordgren (10.1016/j.bbalip.2014.08.006_bb0790) 2013; 14 Borgeat (10.1016/j.bbalip.2014.08.006_bb0485) 1979; 76 Marcheselli (10.1016/j.bbalip.2014.08.006_bb0220) 2003; 278 Ariel (10.1016/j.bbalip.2014.08.006_bb0240) 2005; 280 Skulas-Ray (10.1016/j.bbalip.2014.08.006_bb0525) 2011; 93 Ariel (10.1016/j.bbalip.2014.08.006_bb0540) 2012; 3 Cortina (10.1016/j.bbalip.2014.08.006_bb0370) 2010; 51 Coussens (10.1016/j.bbalip.2014.08.006_bb0080) 2002; 420 Tabas (10.1016/j.bbalip.2014.08.006_bb0340) 2013; 339 |
| References_xml | – volume: vol. 8 start-page: 1 year: 1990 end-page: 22 ident: bb0200 article-title: Supply of n publication-title: Nutrition and the Brain – volume: 21 start-page: 1187 year: 2012 end-page: 1199 ident: bb0605 article-title: 14S,21R-dihydroxy-docosahexaenoic acid treatment enhances mesenchymal stem cell amelioration of renal ischemia/reperfusion injury publication-title: Stem Cells Dev. – volume: 285 start-page: 18301 year: 2010 end-page: 18308 ident: bb0760 article-title: Neuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survival publication-title: J. Biol. Chem. – volume: 13 start-page: 868 year: 2007 end-page: 873 ident: bb0355 article-title: Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis publication-title: Nat. Med. – volume: 49 start-page: 123 year: 2009 end-page: 150 ident: bb0620 article-title: Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation publication-title: Annu. Rev. Pharmacol. Toxicol. – volume: 420 start-page: 846 year: 2002 end-page: 852 ident: bb0100 article-title: Points of control in inflammation publication-title: Nature – volume: 305 start-page: G818 year: 2013 end-page: G828 ident: bb0410 article-title: Intravenous fish oil lipid emulsion promotes a shift toward anti-inflammatory proresolving lipid mediators publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. – volume: 6 start-page: 411 year: 2010 end-page: 417 ident: bb0650 article-title: Metabolic oxidation regulates embryonic stem cell differentiation publication-title: Nat. Chem. Biol. – volume: 103 start-page: 11276 year: 2006 end-page: 11281 ident: bb0755 article-title: Transgenic mice rich in endogenous n− publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 40 start-page: 249 year: 2005 end-page: 257 ident: bb0405 article-title: Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase–10(S)-hydroxydocosahexaenoic acid and 10,20-dihydroxydocosahexaenoic acid publication-title: Lipids – start-page: 42 year: 2006 end-page: 45 ident: bb0535 article-title: A novel approach to resolving inflammation publication-title: Sci. Am. – volume: 192 start-page: 1197 year: 2000 end-page: 1204 ident: bb0050 article-title: Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing publication-title: J. Exp. Med. – volume: 282 start-page: 9323 year: 2007 end-page: 9334 ident: bb0470 article-title: Resolvin D1 and its aspirin-triggered 17 publication-title: J. Biol. Chem. – volume: 120 start-page: e60 year: 2012 end-page: e72 ident: bb0560 article-title: Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators publication-title: Blood – volume: 62 start-page: 2437 year: 1994 end-page: 2447 ident: bb0210 article-title: Lipoxygenation of docosahexaenoic acid by the rat pineal body publication-title: J. Neurochem. – volume: 177 start-page: 1576 year: 2010 end-page: 1591 ident: bb0025 article-title: Novel resolution mechanisms in acute inflammation: to resolve or not? publication-title: Am. J. Pathol. – volume: 171 start-page: 6856 year: 2003 end-page: 6865 ident: bb0660 article-title: Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators publication-title: J. Immunol. – volume: 32 start-page: 470 year: 2011 end-page: 477 ident: bb0585 article-title: Monocyte trafficking in acute and chronic inflammation publication-title: Trends Immunol. – volume: 1212 start-page: 1 year: 1994 end-page: 25 ident: bb0125 article-title: Lipoxin biosynthesis and its impact in inflammatory and vascular events publication-title: Biochim. Biophys. Acta – volume: 229 start-page: 1 year: 1988 end-page: 14 ident: bb0300 article-title: Lipoxins: a new series of eicosanoids (biosynthesis, stereochemistry, and biological activities) publication-title: Adv. Exp. Med. Biol. – volume: 27 start-page: 2573 year: 2013 end-page: 2583 ident: bb0575 article-title: The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype publication-title: FASEB J. – volume: 51 start-page: 923 year: 2010 end-page: 932 ident: bb0600 article-title: Novel 14,21-dihydroxy-docosahexaenoic acids: structures, formation pathways, and enhancement of wound healing publication-title: J. Lipid Res. – volume: 178 start-page: 496 year: 2007 end-page: 502 ident: bb0685 article-title: Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness publication-title: J. Immunol. – volume: 287 start-page: 10070 year: 2012 end-page: 10080 ident: bb0615 article-title: Role of basic science in the development of new medicines: examples from the eicosanoid field publication-title: J. Biol. Chem. – year: 2005 ident: bb0290 article-title: Synthetic study of lipid mediators; Doctoral thesis – volume: 54 start-page: 4109 year: 2013 end-page: 4116 ident: bb0720 article-title: Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery publication-title: Invest. Ophthalmol. Vis. Sci. – volume: 32 start-page: 203 year: 2012 end-page: 227 ident: bb0550 article-title: Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids publication-title: Annu. Rev. Nutr. – volume: 25 start-page: 2399 year: 2011 end-page: 2407 ident: bb0590 article-title: Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice publication-title: FASEB J. – volume: 118 start-page: e192 year: 2011 end-page: e208 ident: bb0265 article-title: Transcriptomic analyses of murine resolution-phase macrophages publication-title: Blood – volume: 53 start-page: 1695 year: 2012 end-page: 1698 ident: bb0295 article-title: Stereocontrolled total synthesis of neuroprotectin D1/protectin D1 and its aspirin-triggered stereoisomer publication-title: Tetrahedron Lett. – volume: 126 start-page: 13 year: 2008 end-page: 30 ident: bb0505 article-title: TNFalpha blockade in human diseases: an overview of efficacy and safety publication-title: Clin. Immunol. – volume: 25 start-page: 382 year: 2011 end-page: 388 ident: bb0680 article-title: Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation publication-title: FASEB J. – volume: 190 start-page: 6378 year: 2013 end-page: 6388 ident: bb0670 article-title: Inhaled carbon monoxide accelerates resolution of inflammation via unique pro-resolving mediator–heme oxygenase-1 circuits publication-title: J. Immunol. – volume: 420 start-page: 860 year: 2002 end-page: 867 ident: bb0080 article-title: Inflammation and cancer publication-title: Nature – volume: 74 start-page: 490 year: 2013 end-page: 495 ident: bb0740 article-title: Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma publication-title: Ann. Neurol. – volume: vol. 23 start-page: 242 year: 1982 ident: bb0030 article-title: Current topics in inflammation and infection publication-title: International Academy of Pathology Monograph – volume: 39 start-page: 885 year: 2013 end-page: 898 ident: bb0785 article-title: Plasticity of leukocytic exudates in resolving acute inflammation is regulated by microRNA and proresolving mediators publication-title: Immunity – volume: 5 start-page: 698 year: 1999 end-page: 701 ident: bb0415 article-title: Inducible cycloxygenase may have anti-inflammatory properties publication-title: Nat. Med. – volume: 183 start-page: 3383 year: 2009 end-page: 3389 ident: bb0800 article-title: 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis publication-title: J. Immunol. – volume: 220 start-page: 568 year: 1983 end-page: 575 ident: bb0055 article-title: Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation publication-title: Science – volume: 280 start-page: 43079 year: 2005 end-page: 43086 ident: bb0240 article-title: The docosatriene protectin D1 is produced by T publication-title: J. Biol. Chem. – volume: 154 start-page: 1243 year: 1981 end-page: 1248 ident: bb0495 article-title: Functional characterization of synthetic leukotriene B and its stereochemical isomers publication-title: J. Exp. Med. – volume: 9 start-page: e102362 year: 2014 ident: bb0580 article-title: Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages publication-title: PLoS One – volume: 484 start-page: 524 year: 2012 end-page: 528 ident: bb0630 article-title: Infection regulates pro-resolving mediators that lower antibiotic requirements publication-title: Nature – volume: 122 start-page: 305 year: 2004 end-page: 321 ident: bb0150 article-title: A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution publication-title: Histochem. Cell Biol. – volume: 21 start-page: 2257 year: 2007 end-page: 2266 ident: bb0795 article-title: Interdependence of lipoxin A4 and heme-oxygenase in counter-regulating inflammation during corneal wound healing publication-title: FASEB J. – volume: 237 start-page: 1171 year: 1987 end-page: 1176 ident: bb0115 article-title: Leukotrienes and lipoxins: structures, biosynthesis, and biological effects publication-title: Science – volume: 263 start-page: 217 year: 2004 end-page: 225 ident: bb0185 article-title: Omega-3 fatty acids from fish oils and cardiovascular disease publication-title: Mol. Cell. Biochem. – volume: 52 start-page: 1601 year: 2011 end-page: 1608 ident: bb0750 article-title: The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis publication-title: Epilepsia – volume: 20 start-page: S152 year: 2002 end-page: S157 ident: bb0500 article-title: Side effects of anti-TNF therapy: current knowledge publication-title: Clin. Exp. Rheumatol. – volume: 125 start-page: 741 year: 1984 end-page: 747 ident: bb0205 article-title: Docosahexaenoic acid (22:6, n publication-title: Biochem. Biophys. Res. Commun. – volume: 14 start-page: 51 year: 2013 ident: bb0790 article-title: Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust publication-title: Respir. Res. – volume: 173 start-page: 1284 year: 2004 end-page: 1291 ident: bb0465 article-title: The lectin-like domain of complement receptor 3 protects endothelial barrier function from activated neutrophils publication-title: J. Immunol. – volume: 115 start-page: 2774 year: 2005 end-page: 2783 ident: bb0710 article-title: A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease publication-title: J. Clin. Invest. – volume: 184 start-page: 6418 year: 2010 end-page: 6426 ident: bb0805 article-title: Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production publication-title: J. Immunol. – volume: 105 start-page: 1897 year: 2002 end-page: 1903 ident: bb0180 article-title: Early protection against sudden death by n publication-title: Circulation – volume: 78 start-page: 107 year: 2005 end-page: 116 ident: bb0235 article-title: Rainbow trout ( publication-title: Prostaglandins Lipid Mediat. – volume: 13 start-page: 632 year: 2013 end-page: 640 ident: bb0390 article-title: Resolution phase lipid mediators of inflammation: agonists of resolution publication-title: Curr. Opin. Pharmacol. – volume: 7 start-page: 1209 year: 2006 end-page: 1216 ident: bb0345 article-title: Apoptotic neutrophils and T cells sequester chemokines during immune response resolution via modulation of CCR5 expression publication-title: Nat. Immunol. – volume: 54 start-page: 6269 year: 2013 end-page: 6279 ident: bb0745 article-title: Neuroprotectin D1 reduces the severity of herpes simplex virus-induced corneal immunopathology publication-title: Invest. Ophthalmol. Vis. Sci. – volume: 118 start-page: e192 year: 2011 end-page: e208 ident: bb0545 article-title: Transcriptomic analyses of murine resolution-phase macrophages publication-title: Blood – year: 2004 ident: bb0075 article-title: Cells, Tissues, and Disease: Principles of General Pathology – start-page: 181 year: 1982 end-page: 206 ident: bb0440 article-title: Adventures and excursions in bioassay: the stepping stones to prostacyclin publication-title: Nobel Prizes, Presentations, Biographies and Lectures – volume: 3 start-page: 401 year: 2004 end-page: 416 ident: bb0145 article-title: Inflammatory resolution: new opportunities for drug discovery publication-title: Nat. Rev. Drug Discov. – volume: 82 start-page: 345 year: 1929 end-page: 367 ident: bb0165 article-title: A new deficiency disease produced by the rigid exclusion of fat from the diet publication-title: J. Biol. Chem. – volume: 275 start-page: 31 year: 1995 end-page: 37 ident: bb0515 article-title: Potent and selective inhibitors of leukotriene A publication-title: J. Pharmacol. Exp. Ther. – volume: 191 start-page: 4288 year: 2013 end-page: 4298 ident: bb0780 article-title: Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis publication-title: J. Immunol. – year: 2010 ident: bb0645 article-title: Fundamentals of Inflammation – volume: 18 start-page: 976 year: 2011 end-page: 987 ident: bb0245 article-title: Novel proresolving aspirin-triggered DHA pathway publication-title: Chem. Biol. – volume: 583 start-page: 3478 year: 2009 end-page: 3484 ident: bb0320 article-title: Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation publication-title: FEBS Lett. – volume: 26 start-page: 1755 year: 2012 end-page: 1765 ident: bb0270 article-title: Macrophage pro-resolving mediator maresin 1 stimulates tissue regeneration and controls pain publication-title: FASEB J. – volume: vol. 2 start-page: 765 year: 1990 end-page: 778 ident: bb0400 article-title: The unique characteristics of the purified 5-lipoxygenase from potato tubers and the proposed mechanism of formation of leukotrienes and lipoxins publication-title: Biological Oxidation Systems – volume: 447 start-page: 869 year: 2007 end-page: 874 ident: bb0380 article-title: Resolvin E1 and protectin D1 activate inflammation-resolution programmes publication-title: Nature – volume: 26 start-page: 1755 year: 2012 end-page: 1765 ident: bb0570 article-title: Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain publication-title: FASEB J. – volume: 164 start-page: 1663 year: 2000 end-page: 1667 ident: bb0135 article-title: Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages publication-title: J. Immunol. – year: 2005 ident: bb0015 article-title: Fish, Omega-3 and Human Health – volume: 5 start-page: 405 year: 2005 end-page: 411 ident: bb0425 article-title: Aspirin and steroids: new mechanistic findings and avenues for drug discovery publication-title: Curr. Op. Pharmacol. – volume: 2 start-page: 612 year: 2001 end-page: 619 ident: bb0110 article-title: Lipid mediator class switching during acute inflammation: signals in resolution publication-title: Nat. Immunol. – volume: 51 start-page: 804 year: 2010 end-page: 810 ident: bb0370 article-title: Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA publication-title: Invest. Ophthalmol. Vis. Sci. – volume: 277 start-page: 1398 year: 2002 end-page: 1404 ident: bb0635 article-title: Leukotriene A publication-title: J. Biol. Chem. – volume: 32 start-page: 6313 year: 1993 end-page: 6319 ident: bb0455 article-title: Lipoxin A publication-title: Biochemistry (Mosc) – volume: 127 start-page: 810 year: 2014 end-page: 814 ident: bb0770 article-title: Protectin D1 promotes resolution of inflammation in a murine model of lipopolysaccharide-induced acute lung injury via enhancing neutrophil apoptosis publication-title: Chin. Med. J. – volume: 284 start-page: 17877 year: 2009 end-page: 17882 ident: bb0675 article-title: Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1 publication-title: J. Biol. Chem. – volume: 3 start-page: 1940 year: 2013 ident: bb0160 article-title: Novel n− publication-title: Sci. Rep. – volume: 82 start-page: 27 year: 2010 end-page: 34 ident: bb0385 article-title: Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils publication-title: Prostaglandins Leukot. Essent. Fat. Acids – volume: 140 start-page: 935 year: 2010 end-page: 950 ident: bb0035 article-title: Anti-inflammatory agents: present and future publication-title: Cell – volume: 6 start-page: 411 year: 2010 end-page: 417 ident: bb0375 article-title: Metabolic oxidation regulates embryonic stem cell differentiation publication-title: Nat. Chem. Biol. – volume: 36 start-page: 118 year: 2005 end-page: 123 ident: bb0225 article-title: Docosahexaenoic acid complexed to albumin elicits high-grade ischemic neuroprotection publication-title: Stroke – volume: 121 start-page: 569 year: 2011 end-page: 581 ident: bb0640 article-title: Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation publication-title: J. Clin. Invest. – year: 1988 ident: bb0395 article-title: Arachidonic acid cascade: the 5-lipoxygenase pathway; Doctoral thesis, Department of Nutrition – volume: 22 start-page: 3595 year: 2008 end-page: 3606 ident: bb0665 article-title: Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators publication-title: FASEB J. – volume: 131 start-page: 353 year: 2013 end-page: 360 ident: bb0695 article-title: Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma publication-title: J. Allergy Clin. Immunol. – volume: 71 start-page: 1081 year: 2012 end-page: 1087 ident: bb0815 article-title: The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis publication-title: Ann. Rheum. Dis. – volume: 23 start-page: 1946 year: 2009 end-page: 1957 ident: bb0735 article-title: Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins publication-title: FASEB J. – volume: 183 start-page: 137 year: 1996 end-page: 146 ident: bb0140 article-title: Lipoxin A publication-title: J. Exp. Med. – volume: 1004 start-page: 158 year: 1989 end-page: 168 ident: bb0330 article-title: On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE publication-title: Biochim. Biophys. Acta – volume: 20 start-page: 664 year: 2014 end-page: 669 ident: bb0335 article-title: Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis publication-title: Nat. Med. – volume: 81 start-page: 689 year: 1984 end-page: 693 ident: bb0510 article-title: Enzyme with dual lipoxygenase activities catalyzes leukotriene A publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 229 start-page: 39 year: 1988 end-page: 49 ident: bb0310 article-title: Lipoxygenase catalyzed oxygenation of hydroxy fatty acids to lipoxins publication-title: Adv. Exp. Med. Biol. – volume: 25 start-page: 101 year: 2007 end-page: 137 ident: bb0420 article-title: Resolution phases of inflammation: novel endogenous anti-inflammatory and pro-resolving lipid mediators and pathways publication-title: Annu. Rev. Immunol. – volume: 101 start-page: 15178 year: 2004 end-page: 15183 ident: bb0450 article-title: Aspirin triggers anti-inflammatory 15-epi-lipoxin A publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 183 start-page: 2089 year: 2009 end-page: 2096 ident: bb0460 article-title: Effects of low-dose aspirin on acute inflammatory responses in humans publication-title: J. Immunol. – reference: C.N. Serhan, Resolvins: biotemplates for novel therapeutic interventions, in: U.S. Patent 7,585,856 and Application Publication 2004/0116408 A1, Brigham and Women's Hospital, 2004. – volume: 88 start-page: 5 year: 2013 end-page: 13 ident: bb0010 article-title: A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution publication-title: Prostaglandins Leukot. Essent. Fat. Acids – year: 2007 ident: bb0490 article-title: Advanced Organic Chemistry, Part A: Structure and Mechanisms – volume: 280 start-page: 15267 year: 2005 end-page: 15278 ident: bb0230 article-title: A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense publication-title: J. Biol. Chem. – volume: 24 start-page: 323 year: 2003 end-page: 326 ident: bb0130 article-title: A magic bullet for mucosal protection … and aspirin is the trigger! publication-title: Trends Pharmacol. Sci. – volume: 420 start-page: 868 year: 2002 end-page: 878 ident: bb0085 article-title: Inflammation in atherosclerosis publication-title: Nature – volume: 92 start-page: 9475 year: 1995 end-page: 9479 ident: bb0430 article-title: Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell–leukocyte interactions publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 51 start-page: 2018 year: 2010 end-page: 2031 ident: bb0060 article-title: Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1 publication-title: J. Lipid Res. – start-page: 119 year: 1999 end-page: 144 ident: bb0315 article-title: Transcellular regulation of eicosanoid biosynthesis publication-title: Eicosanoid Protocols – volume: 206 start-page: 15 year: 2009 end-page: 23 ident: bb0555 article-title: Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions publication-title: J. Exp. Med. – volume: 99 start-page: 2452 year: 1999 end-page: 2457 ident: bb0175 article-title: Prevention of sudden cardiac death by dietary pure w publication-title: Circulation – volume: 122 start-page: 787 year: 2012 end-page: 795 ident: bb0255 article-title: Macrophage plasticity and polarization: in vivo veritas publication-title: J. Clin. Invest. – volume: 177 start-page: 5902 year: 2006 end-page: 5911 ident: bb0705 article-title: Resolvin D series and protectin D1 mitigate acute kidney injury publication-title: J. Immunol. – start-page: 6586 year: 2000 end-page: 6591 ident: bb0445 article-title: Spatial requirements for 15-( publication-title: J. Biol. Chem. – volume: 176 start-page: 74 year: 2010 end-page: 84 ident: bb0810 article-title: Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury publication-title: Am. J. Pathol. – volume: 206 start-page: 15 year: 2009 end-page: 23 ident: bb0275 article-title: Maresins: novel macrophage mediators with potent anti-inflammatory and pro-resolving actions publication-title: J. Exp. Med. – volume: 339 start-page: 166 year: 2013 end-page: 172 ident: bb0340 article-title: Anti-inflammatory therapy in chronic disease: challenges and opportunities publication-title: Science – volume: 1821 start-page: 1415 year: 2012 end-page: 1424 ident: bb0565 article-title: Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS publication-title: Biochim. Biophys. Acta – volume: 110 start-page: 1546 year: 2012 end-page: 1548 ident: bb0260 article-title: Targeting a monocyte subset to reduce inflammation publication-title: Circ. Res. – volume: 196 start-page: 1025 year: 2002 end-page: 1037 ident: bb0045 article-title: Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter pro-inflammation signals publication-title: J. Exp. Med. – volume: 484 start-page: 524 year: 2012 end-page: 528 ident: bb0285 article-title: Infection regulates pro-resolving mediators that lower antibiotic requirements publication-title: Nature – volume: 261 start-page: 16340 year: 1986 end-page: 16345 ident: bb0305 article-title: Lipoxin A publication-title: J Biol Chem. – volume: 111 start-page: 5922 year: 2011 end-page: 5943 ident: bb0480 article-title: Resolvins and protectins in inflammation-resolution publication-title: Chem. Rev. – volume: 101 start-page: 8491 year: 2004 end-page: 8496 ident: bb0070 article-title: Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 284 start-page: 21599 year: 2009 end-page: 21612 ident: bb0725 article-title: Lipidomic analysis of dynamic eicosanoid responses during the induction and resolution of Lyme arthritis publication-title: J. Biol. Chem. – volume: 6 start-page: 1191 year: 2005 end-page: 1197 ident: bb0040 article-title: Resolution of inflammation: the beginning programs the end publication-title: Nat. Immunol. – volume: 81 start-page: 1635 year: 2010 end-page: 1643 ident: bb0530 article-title: Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 fatty acids and low-dose aspirin publication-title: J. Periodontol. – volume: 236 start-page: 122 year: 2012 end-page: 130 ident: bb0775 article-title: Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke publication-title: Exp. Neurol. – volume: 420 start-page: 879 year: 2002 end-page: 884 ident: bb0090 article-title: Inflammation and therapeutic vaccination in CNS diseases publication-title: Nature – volume: 20 start-page: 2537 year: 2006 end-page: 2539 ident: bb0715 article-title: Docosahexanenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D1 and 17 publication-title: FASEB J. – volume: 287 start-page: 10070 year: 2012 end-page: 10080 ident: bb0095 article-title: Role of basic science in the development of new medicines: examples from the eicosanoid field publication-title: J. Biol. Chem. – volume: 257 start-page: 7056 year: 1982 end-page: 7067 ident: bb0325 article-title: Formation of a novel dihydroxy acid from arachidonic acid by lipoxygenase-catalyzed double oxygenation in rat mononuclear cells and human leukocytes publication-title: J. Biol. Chem. – volume: 461 start-page: 1287 year: 2009 end-page: 1291 ident: bb0475 article-title: Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis publication-title: Nature – volume: 31 start-page: 15072 year: 2011 end-page: 15085 ident: bb0350 article-title: Resolving TRPV1 and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1 publication-title: J. Neurosci. – volume: 79 start-page: 201 year: 2008 end-page: 207 ident: bb0730 article-title: Neuroprotectin D1 inhibits retinal ganglion cell death following axotomy publication-title: Prostaglandins Leukot. Essent. Fat. Acids – volume: 376 start-page: 1713 year: 2010 end-page: 1714 ident: bb0520 article-title: Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials publication-title: Lancet – volume: 25 start-page: 3032 year: 2005 end-page: 3040 ident: bb0195 article-title: A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model publication-title: J. Neurosci. – volume: 93 start-page: 243 year: 2011 end-page: 252 ident: bb0525 article-title: Dose–response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia publication-title: Am. J. Clin. Nutr. – volume: 286 start-page: 4443 year: 2011 end-page: 4453 ident: bb0610 article-title: 14S,21R-dihydroxydocosahexaenoic acid remedies impaired healing and mesenchymal stem cell functions in diabetic wounds publication-title: J. Biol. Chem. – volume: 29 start-page: 263 year: 2006 end-page: 271 ident: bb0005 article-title: Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors publication-title: Trends Neurosci. – volume: 278 start-page: 14677 year: 2003 end-page: 14687 ident: bb0065 article-title: Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood and glial cells: autacoids in anti-inflammation publication-title: J. Biol. Chem. – start-page: 153 year: 1982 end-page: 174 ident: bb0435 article-title: From studies of biochemical mechanisms to novel biological mediators: prostaglandin endoperoxides, thromboxanes and leukotrienes publication-title: Nobel Prizes, Presentations, Biographies and Lecture – volume: 174 start-page: 4345 year: 2005 end-page: 4355 ident: bb0215 article-title: Molecular circuits of resolution: formation and actions of resolvins and protectins publication-title: J. Immunol. – volume: 278 start-page: 43807 year: 2003 end-page: 43817 ident: bb0220 article-title: Novel docosanoids inhibit brain ischemia publication-title: J. Biol. Chem. – volume: 461 start-page: 1287 year: 2009 end-page: 1291 ident: bb0625 article-title: Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis publication-title: Nature – volume: 182 start-page: 3223 year: 2009 end-page: 3232 ident: bb0365 article-title: Acute changes in dietary omega-3 and omega-6 polyunsaturated fatty acids have a pronounced impact on survival following ischemic renal injury and formation of renoprotective docosahexaenoic acid-derived protectin D1 publication-title: J. Immunol. – volume: 135 start-page: 687 year: 2005 end-page: 694 ident: bb0170 article-title: Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n publication-title: J. Nutr. – volume: 25 start-page: 561 year: 2011 end-page: 568 ident: bb0700 article-title: Eosinophils promote resolution of acute periotonitis by producing proresolving mediators in mice publication-title: FASEB J. – volume: 92 start-page: 8383 year: 1995 end-page: 8387 ident: bb0655 article-title: Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 43 start-page: 131 year: 2011 end-page: 138 ident: bb0360 article-title: Neuroprotectin D1 induces neuronal survival and downregulation of amyloidogenic processing in Alzheimer's disease cellular models publication-title: Mol. Neurobiol. – volume: 5 start-page: 762 year: 2013 end-page: 775 ident: bb0690 article-title: Toll-like receptor 7 stimulates production of specialized pro-resolving lipid mediators and promotes resolution of airway inflammation publication-title: Mol. Med. – volume: 286 start-page: F189 year: 2004 end-page: F201 ident: bb0120 article-title: Lipoxins: endogenous regulators of inflammation publication-title: Am. J. Physiol. Renal Physiol. – volume: 73 start-page: 155 year: 2004 end-page: 172 ident: bb0155 article-title: Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis publication-title: Prostaglandins Lipid Mediat. – volume: 76 start-page: 2148 year: 1979 end-page: 2152 ident: bb0485 article-title: Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187 publication-title: Proc. Natl. Acad. Sci. U. S. A. – volume: 153 start-page: 112 year: 2013 end-page: 125 ident: bb0765 article-title: The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza publication-title: Cell – volume: 8 start-page: e73085 year: 2013 ident: bb0820 article-title: Omega-3 polyunsaturated fatty acids suppress the cystic lesion formation of peritoneal endometriosis in transgenic mouse models publication-title: PLoS One – volume: 3 start-page: 4 year: 2012 ident: bb0540 article-title: New lives given by cell death: macrophage differentiation following their encounter with apoptotic leukocytes during the resolution of inflammation publication-title: Front. Immunol. – volume: 176 start-page: 1848 year: 2006 end-page: 1859 ident: bb0250 article-title: Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes publication-title: J. Immunol. – volume: 36 start-page: 945 year: 2001 end-page: 959 ident: bb0020 article-title: Mechanisms of action of docosahexaenoic acid in the nervous system publication-title: Lipids – volume: 30 start-page: 69 year: 2004 end-page: 95 ident: bb0105 article-title: Novel endogenous small molecules as the checkpoint controllers in inflammation and resolution: entrée for resoleomics publication-title: Rheum. Dis. Clin. N. Am. – volume: 42 start-page: 672 year: 2004 end-page: 679 ident: bb0190 article-title: Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study publication-title: Int. J. Clin. Pharmacol. Ther. – volume: 187 start-page: 5408 year: 2011 end-page: 5418 ident: bb0595 article-title: Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype publication-title: J. Immunol. – volume: 25 start-page: 2399 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0590 article-title: Resolvin D1 decreases adipose tissue macrophage accumulation and improves insulin sensitivity in obese-diabetic mice publication-title: FASEB J. doi: 10.1096/fj.10-178657 – volume: 31 start-page: 15072 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0350 article-title: Resolving TRPV1 and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1 publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.2443-11.2011 – volume: 27 start-page: 2573 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0575 article-title: The novel 13S,14S-epoxy-maresin is converted by human macrophages to maresin1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype publication-title: FASEB J. doi: 10.1096/fj.13-227728 – volume: 24 start-page: 323 year: 2003 ident: 10.1016/j.bbalip.2014.08.006_bb0130 article-title: A magic bullet for mucosal protection … and aspirin is the trigger! publication-title: Trends Pharmacol. Sci. doi: 10.1016/S0165-6147(03)00166-4 – volume: 447 start-page: 869 year: 2007 ident: 10.1016/j.bbalip.2014.08.006_bb0380 article-title: Resolvin E1 and protectin D1 activate inflammation-resolution programmes publication-title: Nature doi: 10.1038/nature05877 – volume: 183 start-page: 3383 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0800 article-title: 12/15-lipoxygenase counteracts inflammation and tissue damage in arthritis publication-title: J. Immunol. doi: 10.4049/jimmunol.0900327 – volume: 40 start-page: 249 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0405 article-title: Novel oxylipins formed from docosahexaenoic acid by potato lipoxygenase–10(S)-hydroxydocosahexaenoic acid and 10,20-dihydroxydocosahexaenoic acid publication-title: Lipids doi: 10.1007/s11745-005-1379-z – volume: 461 start-page: 1287 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0625 article-title: Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis publication-title: Nature doi: 10.1038/nature08541 – volume: vol. 2 start-page: 765 year: 1990 ident: 10.1016/j.bbalip.2014.08.006_bb0400 article-title: The unique characteristics of the purified 5-lipoxygenase from potato tubers and the proposed mechanism of formation of leukotrienes and lipoxins – volume: 99 start-page: 2452 year: 1999 ident: 10.1016/j.bbalip.2014.08.006_bb0175 article-title: Prevention of sudden cardiac death by dietary pure w−3 polyunsaturated fatty acids in dogs publication-title: Circulation doi: 10.1161/01.CIR.99.18.2452 – volume: 278 start-page: 14677 year: 2003 ident: 10.1016/j.bbalip.2014.08.006_bb0065 article-title: Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood and glial cells: autacoids in anti-inflammation publication-title: J. Biol. Chem. doi: 10.1074/jbc.M300218200 – volume: 286 start-page: F189 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0120 article-title: Lipoxins: endogenous regulators of inflammation publication-title: Am. J. Physiol. Renal Physiol. doi: 10.1152/ajprenal.00224.2003 – volume: 92 start-page: 9475 year: 1995 ident: 10.1016/j.bbalip.2014.08.006_bb0430 article-title: Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell–leukocyte interactions publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.92.21.9475 – volume: 420 start-page: 846 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0100 article-title: Points of control in inflammation publication-title: Nature doi: 10.1038/nature01320 – volume: 177 start-page: 1576 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0025 article-title: Novel resolution mechanisms in acute inflammation: to resolve or not? publication-title: Am. J. Pathol. doi: 10.2353/ajpath.2010.100322 – volume: 461 start-page: 1287 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0475 article-title: Resolvin D2 is a potent regulator of leukocytes and controls microbial sepsis publication-title: Nature doi: 10.1038/nature08541 – volume: 32 start-page: 470 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0585 article-title: Monocyte trafficking in acute and chronic inflammation publication-title: Trends Immunol. doi: 10.1016/j.it.2011.05.001 – volume: 127 start-page: 810 year: 2014 ident: 10.1016/j.bbalip.2014.08.006_bb0770 article-title: Protectin D1 promotes resolution of inflammation in a murine model of lipopolysaccharide-induced acute lung injury via enhancing neutrophil apoptosis publication-title: Chin. Med. J. doi: 10.3760/cma.j.issn.0366-6999.20131104 – volume: 5 start-page: 698 year: 1999 ident: 10.1016/j.bbalip.2014.08.006_bb0415 article-title: Inducible cycloxygenase may have anti-inflammatory properties publication-title: Nat. Med. doi: 10.1038/9550 – volume: 25 start-page: 382 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0680 article-title: Poxytrins, a class of oxygenated products from polyunsaturated fatty acids, potently inhibit blood platelet aggregation publication-title: FASEB J. doi: 10.1096/fj.10-161836 – volume: 36 start-page: 118 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0225 article-title: Docosahexaenoic acid complexed to albumin elicits high-grade ischemic neuroprotection publication-title: Stroke doi: 10.1161/01.STR.0000149620.74770.2e – volume: 305 start-page: G818 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0410 article-title: Intravenous fish oil lipid emulsion promotes a shift toward anti-inflammatory proresolving lipid mediators publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00106.2013 – volume: 284 start-page: 21599 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0725 article-title: Lipidomic analysis of dynamic eicosanoid responses during the induction and resolution of Lyme arthritis publication-title: J. Biol. Chem. doi: 10.1074/jbc.M109.003822 – volume: 20 start-page: S152 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0500 article-title: Side effects of anti-TNF therapy: current knowledge publication-title: Clin. Exp. Rheumatol. – volume: 183 start-page: 2089 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0460 article-title: Effects of low-dose aspirin on acute inflammatory responses in humans publication-title: J. Immunol. doi: 10.4049/jimmunol.0900477 – volume: 206 start-page: 15 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0555 article-title: Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions publication-title: J. Exp. Med. doi: 10.1084/jem.20081880 – volume: 125 start-page: 741 year: 1984 ident: 10.1016/j.bbalip.2014.08.006_bb0205 article-title: Docosahexaenoic acid (22:6, n−3) is metabolized to lipoxygenase reaction products in the retina publication-title: Biochem. Biophys. Res. Commun. doi: 10.1016/0006-291X(84)90601-6 – volume: 420 start-page: 879 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0090 article-title: Inflammation and therapeutic vaccination in CNS diseases publication-title: Nature doi: 10.1038/nature01325 – volume: 131 start-page: 353 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0695 article-title: Dysregulated synthesis of protectin D1 in eosinophils from patients with severe asthma publication-title: J. Allergy Clin. Immunol. doi: 10.1016/j.jaci.2012.07.048 – start-page: 6586 year: 2000 ident: 10.1016/j.bbalip.2014.08.006_bb0445 article-title: Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2 publication-title: J. Biol. Chem. doi: 10.1074/jbc.275.9.6586 – volume: 126 start-page: 13 year: 2008 ident: 10.1016/j.bbalip.2014.08.006_bb0505 article-title: TNFalpha blockade in human diseases: an overview of efficacy and safety publication-title: Clin. Immunol. doi: 10.1016/j.clim.2007.08.012 – volume: 121 start-page: 569 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0640 article-title: Pro-resolving actions and stereoselective biosynthesis of 18S E-series resolvins in human leukocytes and murine inflammation publication-title: J. Clin. Invest. doi: 10.1172/JCI42545 – volume: 51 start-page: 923 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0600 article-title: Novel 14,21-dihydroxy-docosahexaenoic acids: structures, formation pathways, and enhancement of wound healing publication-title: J. Lipid Res. doi: 10.1194/jlr.M000059 – volume: 20 start-page: 664 year: 2014 ident: 10.1016/j.bbalip.2014.08.006_bb0335 article-title: Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis publication-title: Nat. Med. doi: 10.1038/nm.3549 – volume: 1004 start-page: 158 year: 1989 ident: 10.1016/j.bbalip.2014.08.006_bb0330 article-title: On the relationship between leukotriene and lipoxin production by human neutrophils: evidence for differential metabolism of 15-HETE and 5-HETE publication-title: Biochim. Biophys. Acta doi: 10.1016/0005-2760(89)90264-6 – volume: 177 start-page: 5902 year: 2006 ident: 10.1016/j.bbalip.2014.08.006_bb0705 article-title: Resolvin D series and protectin D1 mitigate acute kidney injury publication-title: J. Immunol. doi: 10.4049/jimmunol.177.9.5902 – volume: 285 start-page: 18301 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0760 article-title: Neuroprotectin D1 induces dephosphorylation of Bcl-xL in a PP2A-dependent manner during oxidative stress and promotes retinal pigment epithelial cell survival publication-title: J. Biol. Chem. doi: 10.1074/jbc.M109.095232 – volume: 280 start-page: 43079 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0240 article-title: The docosatriene protectin D1 is produced by TH2 skewing and promotes human T cell apoptosis via lipid raft clustering publication-title: J. Biol. Chem. doi: 10.1074/jbc.M509796200 – volume: 237 start-page: 1171 year: 1987 ident: 10.1016/j.bbalip.2014.08.006_bb0115 article-title: Leukotrienes and lipoxins: structures, biosynthesis, and biological effects publication-title: Science doi: 10.1126/science.2820055 – volume: 76 start-page: 2148 year: 1979 ident: 10.1016/j.bbalip.2014.08.006_bb0485 article-title: Arachidonic acid metabolism in polymorphonuclear leukocytes: effects of ionophore A23187 publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.76.5.2148 – year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0015 – volume: 287 start-page: 10070 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0095 article-title: Role of basic science in the development of new medicines: examples from the eicosanoid field publication-title: J. Biol. Chem. doi: 10.1074/jbc.X112.351437 – volume: 122 start-page: 305 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0150 article-title: A search for endogenous mechanisms of anti-inflammation uncovers novel chemical mediators: missing links to resolution publication-title: Histochem. Cell Biol. doi: 10.1007/s00418-004-0695-8 – volume: 32 start-page: 6313 year: 1993 ident: 10.1016/j.bbalip.2014.08.006_bb0455 article-title: Lipoxin A4 metabolism by differentiated HL-60 cells and human monocytes: conversion to novel 15-oxo and dihydro products publication-title: Biochemistry (Mosc) doi: 10.1021/bi00076a002 – volume: 183 start-page: 137 year: 1996 ident: 10.1016/j.bbalip.2014.08.006_bb0140 article-title: Lipoxin A4 and B4 are potent stimuli for human monocyte migration and adhesion: selective inactivation by dehydrogenation and reduction publication-title: J. Exp. Med. doi: 10.1084/jem.183.1.137 – volume: 191 start-page: 4288 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0780 article-title: Maresin 1, a proresolving lipid mediator derived from omega-3 polyunsaturated fatty acids, exerts protective actions in murine models of colitis publication-title: J. Immunol. doi: 10.4049/jimmunol.1202743 – year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0290 – volume: 53 start-page: 1695 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0295 article-title: Stereocontrolled total synthesis of neuroprotectin D1/protectin D1 and its aspirin-triggered stereoisomer publication-title: Tetrahedron Lett. doi: 10.1016/j.tetlet.2012.01.032 – volume: 583 start-page: 3478 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0320 article-title: Full characterization of PDX, a neuroprotectin/protectin D1 isomer, which inhibits blood platelet aggregation publication-title: FEBS Lett. doi: 10.1016/j.febslet.2009.10.004 – volume: 280 start-page: 15267 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0230 article-title: A role for the mouse 12/15-lipoxygenase pathway in promoting epithelial wound healing and host defense publication-title: J. Biol. Chem. doi: 10.1074/jbc.M410638200 – volume: 18 start-page: 976 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0245 article-title: Novel proresolving aspirin-triggered DHA pathway publication-title: Chem. Biol. doi: 10.1016/j.chembiol.2011.06.008 – volume: 6 start-page: 411 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0375 article-title: Metabolic oxidation regulates embryonic stem cell differentiation publication-title: Nat. Chem. Biol. doi: 10.1038/nchembio.364 – year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0075 – volume: 78 start-page: 107 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0235 article-title: Rainbow trout (Oncorhynchus mykiss) brain cells biosynthesize novel docosahexaenoic acid-derived resolvins and protectins—mediator lipidomic analysis publication-title: Prostaglandins Lipid Mediat. doi: 10.1016/j.prostaglandins.2005.04.004 – volume: 261 start-page: 16340 year: 1986 ident: 10.1016/j.bbalip.2014.08.006_bb0305 article-title: Lipoxin A publication-title: J Biol Chem. doi: 10.1016/S0021-9258(18)66571-8 – volume: 20 start-page: 2537 year: 2006 ident: 10.1016/j.bbalip.2014.08.006_bb0715 article-title: Docosahexanenoic acid (DHA) blunts liver injury by conversion to protective lipid mediators: protectin D1 and 17S-hydroxy-DHA publication-title: FASEB J. doi: 10.1096/fj.06-6250fje – volume: 229 start-page: 39 year: 1988 ident: 10.1016/j.bbalip.2014.08.006_bb0310 article-title: Lipoxygenase catalyzed oxygenation of hydroxy fatty acids to lipoxins publication-title: Adv. Exp. Med. Biol. – volume: 120 start-page: e60 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0560 article-title: Specific lipid mediator signatures of human phagocytes: microparticles stimulate macrophage efferocytosis and pro-resolving mediators publication-title: Blood doi: 10.1182/blood-2012-04-423525 – volume: 51 start-page: 2018 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0060 article-title: Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1 publication-title: J. Lipid Res. doi: 10.1194/jlr.R001131 – volume: 122 start-page: 787 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0255 article-title: Macrophage plasticity and polarization: in vivo veritas publication-title: J. Clin. Invest. doi: 10.1172/JCI59643 – volume: 82 start-page: 27 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0385 article-title: Neuroprotectin D1/protectin D1 stereoselective and specific binding with human retinal pigment epithelial cells and neutrophils publication-title: Prostaglandins Leukot. Essent. Fat. Acids doi: 10.1016/j.plefa.2009.10.010 – volume: 101 start-page: 15178 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0450 article-title: Aspirin triggers anti-inflammatory 15-epi-lipoxin A4 and inhibits thromboxane in a randomized human trial publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0405445101 – volume: 154 start-page: 1243 year: 1981 ident: 10.1016/j.bbalip.2014.08.006_bb0495 article-title: Functional characterization of synthetic leukotriene B and its stereochemical isomers publication-title: J. Exp. Med. doi: 10.1084/jem.154.4.1243 – volume: 6 start-page: 1191 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0040 article-title: Resolution of inflammation: the beginning programs the end publication-title: Nat. Immunol. doi: 10.1038/ni1276 – volume: 101 start-page: 8491 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0070 article-title: Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0402531101 – volume: 5 start-page: 762 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0690 article-title: Toll-like receptor 7 stimulates production of specialized pro-resolving lipid mediators and promotes resolution of airway inflammation publication-title: Mol. Med. – volume: 8 start-page: e73085 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0820 article-title: Omega-3 polyunsaturated fatty acids suppress the cystic lesion formation of peritoneal endometriosis in transgenic mouse models publication-title: PLoS One doi: 10.1371/journal.pone.0073085 – volume: 110 start-page: 1546 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0260 article-title: Targeting a monocyte subset to reduce inflammation publication-title: Circ. Res. doi: 10.1161/RES.0b013e31825ec26d – start-page: 119 year: 1999 ident: 10.1016/j.bbalip.2014.08.006_bb0315 article-title: Transcellular regulation of eicosanoid biosynthesis – volume: 153 start-page: 112 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0765 article-title: The lipid mediator protectin D1 inhibits influenza virus replication and improves severe influenza publication-title: Cell doi: 10.1016/j.cell.2013.02.027 – volume: 42 start-page: 672 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0190 article-title: Docosahexaenoic acid restores endothelial function in children with hyperlipidemia: results from the EARLY study publication-title: Int. J. Clin. Pharmacol. Ther. doi: 10.5414/CPP42672 – volume: 263 start-page: 217 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0185 article-title: Omega-3 fatty acids from fish oils and cardiovascular disease publication-title: Mol. Cell. Biochem. doi: 10.1023/B:MCBI.0000041863.11248.8d – year: 2007 ident: 10.1016/j.bbalip.2014.08.006_bb0490 – volume: 49 start-page: 123 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0620 article-title: Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation publication-title: Annu. Rev. Pharmacol. Toxicol. doi: 10.1146/annurev.pharmtox.011008.145616 – volume: 36 start-page: 945 year: 2001 ident: 10.1016/j.bbalip.2014.08.006_bb0020 article-title: Mechanisms of action of docosahexaenoic acid in the nervous system publication-title: Lipids doi: 10.1007/s11745-001-0805-6 – volume: 192 start-page: 1197 year: 2000 ident: 10.1016/j.bbalip.2014.08.006_bb0050 article-title: Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing publication-title: J. Exp. Med. doi: 10.1084/jem.192.8.1197 – volume: 13 start-page: 868 year: 2007 ident: 10.1016/j.bbalip.2014.08.006_bb0355 article-title: Increased dietary intake of omega-3-polyunsaturated fatty acids reduces pathological retinal angiogenesis publication-title: Nat. Med. doi: 10.1038/nm1591 – volume: 81 start-page: 689 year: 1984 ident: 10.1016/j.bbalip.2014.08.006_bb0510 article-title: Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.81.3.689 – volume: 236 start-page: 122 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0775 article-title: Novel aspirin-triggered neuroprotectin D1 attenuates cerebral ischemic injury after experimental stroke publication-title: Exp. Neurol. doi: 10.1016/j.expneurol.2012.04.007 – start-page: 153 year: 1982 ident: 10.1016/j.bbalip.2014.08.006_bb0435 article-title: From studies of biochemical mechanisms to novel biological mediators: prostaglandin endoperoxides, thromboxanes and leukotrienes – volume: 22 start-page: 3595 year: 2008 ident: 10.1016/j.bbalip.2014.08.006_bb0665 article-title: Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators publication-title: FASEB J. doi: 10.1096/fj.08-112201 – volume: 284 start-page: 17877 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0675 article-title: Selective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1 publication-title: J. Biol. Chem. doi: 10.1074/jbc.M109.003988 – volume: 105 start-page: 1897 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0180 article-title: Early protection against sudden death by n−3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico (GISSI)-Prevenzione publication-title: Circulation doi: 10.1161/01.CIR.0000014682.14181.F2 – volume: 484 start-page: 524 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0285 article-title: Infection regulates pro-resolving mediators that lower antibiotic requirements publication-title: Nature doi: 10.1038/nature11042 – volume: 51 start-page: 804 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0370 article-title: Neuroprotectin D1 synthesis and corneal nerve regeneration after experimental surgery and treatment with PEDF plus DHA publication-title: Invest. Ophthalmol. Vis. Sci. doi: 10.1167/iovs.09-3641 – volume: 6 start-page: 411 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0650 article-title: Metabolic oxidation regulates embryonic stem cell differentiation publication-title: Nat. Chem. Biol. doi: 10.1038/nchembio.364 – volume: 54 start-page: 6269 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0745 article-title: Neuroprotectin D1 reduces the severity of herpes simplex virus-induced corneal immunopathology publication-title: Invest. Ophthalmol. Vis. Sci. doi: 10.1167/iovs.13-12152 – volume: 93 start-page: 243 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0525 article-title: Dose–response effects of omega-3 fatty acids on triglycerides, inflammation, and endothelial function in healthy persons with moderate hypertriglyceridemia publication-title: Am. J. Clin. Nutr. doi: 10.3945/ajcn.110.003871 – volume: 43 start-page: 131 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0360 article-title: Neuroprotectin D1 induces neuronal survival and downregulation of amyloidogenic processing in Alzheimer's disease cellular models publication-title: Mol. Neurobiol. doi: 10.1007/s12035-011-8174-4 – volume: 111 start-page: 5922 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0480 article-title: Resolvins and protectins in inflammation-resolution publication-title: Chem. Rev. doi: 10.1021/cr100396c – volume: 282 start-page: 9323 year: 2007 ident: 10.1016/j.bbalip.2014.08.006_bb0470 article-title: Resolvin D1 and its aspirin-triggered 17R epimer: stereochemical assignments, anti-inflammatory properties and enzymatic inactivation publication-title: J. Biol. Chem. doi: 10.1074/jbc.M609212200 – volume: 14 start-page: 51 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0790 article-title: Maresin-1 reduces the pro-inflammatory response of bronchial epithelial cells to organic dust publication-title: Respir. Res. doi: 10.1186/1465-9921-14-51 – volume: 420 start-page: 868 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0085 article-title: Inflammation in atherosclerosis publication-title: Nature doi: 10.1038/nature01323 – volume: 1212 start-page: 1 year: 1994 ident: 10.1016/j.bbalip.2014.08.006_bb0125 article-title: Lipoxin biosynthesis and its impact in inflammatory and vascular events publication-title: Biochim. Biophys. Acta doi: 10.1016/0005-2760(94)90185-6 – volume: 1821 start-page: 1415 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0565 article-title: Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC–MS/MS publication-title: Biochim. Biophys. Acta doi: 10.1016/j.bbalip.2012.07.011 – volume: 21 start-page: 1187 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0605 article-title: 14S,21R-dihydroxy-docosahexaenoic acid treatment enhances mesenchymal stem cell amelioration of renal ischemia/reperfusion injury publication-title: Stem Cells Dev. doi: 10.1089/scd.2011.0220 – volume: 73 start-page: 155 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0155 article-title: Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis publication-title: Prostaglandins Lipid Mediat. doi: 10.1016/j.prostaglandins.2004.03.005 – volume: vol. 8 start-page: 1 year: 1990 ident: 10.1016/j.bbalip.2014.08.006_bb0200 article-title: Supply of n−3 polyunsaturated fatty acids and their significance in the central nervous system – volume: 176 start-page: 1848 year: 2006 ident: 10.1016/j.bbalip.2014.08.006_bb0250 article-title: Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: assignments of dihydroxy-containing docosatrienes publication-title: J. Immunol. doi: 10.4049/jimmunol.176.3.1848 – volume: 286 start-page: 4443 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0610 article-title: 14S,21R-dihydroxydocosahexaenoic acid remedies impaired healing and mesenchymal stem cell functions in diabetic wounds publication-title: J. Biol. Chem. doi: 10.1074/jbc.M110.100388 – volume: 178 start-page: 496 year: 2007 ident: 10.1016/j.bbalip.2014.08.006_bb0685 article-title: Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness publication-title: J. Immunol. doi: 10.4049/jimmunol.178.1.496 – volume: 79 start-page: 201 year: 2008 ident: 10.1016/j.bbalip.2014.08.006_bb0730 article-title: Neuroprotectin D1 inhibits retinal ganglion cell death following axotomy publication-title: Prostaglandins Leukot. Essent. Fat. Acids doi: 10.1016/j.plefa.2008.09.022 – volume: 21 start-page: 2257 year: 2007 ident: 10.1016/j.bbalip.2014.08.006_bb0795 article-title: Interdependence of lipoxin A4 and heme-oxygenase in counter-regulating inflammation during corneal wound healing publication-title: FASEB J. doi: 10.1096/fj.06-7918com – volume: 88 start-page: 5 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0010 article-title: A quantum theory for the irreplaceable role of docosahexaenoic acid in neural cell signalling throughout evolution publication-title: Prostaglandins Leukot. Essent. Fat. Acids doi: 10.1016/j.plefa.2012.08.005 – volume: 278 start-page: 43807 year: 2003 ident: 10.1016/j.bbalip.2014.08.006_bb0220 article-title: Novel docosanoids inhibit brain ischemia–reperfusion-mediated leukocyte infiltration and pro-inflammatory gene expression publication-title: J. Biol. Chem. doi: 10.1074/jbc.M305841200 – volume: 32 start-page: 203 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0550 article-title: Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids publication-title: Annu. Rev. Nutr. doi: 10.1146/annurev-nutr-071811-150726 – volume: 164 start-page: 1663 year: 2000 ident: 10.1016/j.bbalip.2014.08.006_bb0135 article-title: Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages publication-title: J. Immunol. doi: 10.4049/jimmunol.164.4.1663 – volume: 9 start-page: e102362 year: 2014 ident: 10.1016/j.bbalip.2014.08.006_bb0580 article-title: Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages publication-title: PLoS One doi: 10.1371/journal.pone.0102362 – volume: 3 start-page: 1940 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0160 article-title: Novel n−3 immunoresolvents: structures and actions publication-title: Sci. Rep. doi: 10.1038/srep01940 – volume: 81 start-page: 1635 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0530 article-title: Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 fatty acids and low-dose aspirin publication-title: J. Periodontol. doi: 10.1902/jop.2010.090628 – volume: 25 start-page: 101 year: 2007 ident: 10.1016/j.bbalip.2014.08.006_bb0420 article-title: Resolution phases of inflammation: novel endogenous anti-inflammatory and pro-resolving lipid mediators and pathways publication-title: Annu. Rev. Immunol. doi: 10.1146/annurev.immunol.25.022106.141647 – volume: 275 start-page: 31 year: 1995 ident: 10.1016/j.bbalip.2014.08.006_bb0515 article-title: Potent and selective inhibitors of leukotriene A4 hydrolase: effects on purified enzyme and human polymorphonuclear leukocytes publication-title: J. Pharmacol. Exp. Ther. doi: 10.1016/S0022-3565(25)12050-8 – volume: 82 start-page: 345 year: 1929 ident: 10.1016/j.bbalip.2014.08.006_bb0165 article-title: A new deficiency disease produced by the rigid exclusion of fat from the diet publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(20)78281-5 – volume: 92 start-page: 8383 year: 1995 ident: 10.1016/j.bbalip.2014.08.006_bb0655 article-title: Leukotriene A4 hydrolase: mapping of a henicosapeptide involved in mechanism-based inactivation publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.92.18.8383 – volume: 220 start-page: 568 year: 1983 ident: 10.1016/j.bbalip.2014.08.006_bb0055 article-title: Leukotrienes: mediators of immediate hypersensitivity reactions and inflammation publication-title: Science doi: 10.1126/science.6301011 – start-page: 181 year: 1982 ident: 10.1016/j.bbalip.2014.08.006_bb0440 article-title: Adventures and excursions in bioassay: the stepping stones to prostacyclin – volume: 173 start-page: 1284 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0465 article-title: The lectin-like domain of complement receptor 3 protects endothelial barrier function from activated neutrophils publication-title: J. Immunol. doi: 10.4049/jimmunol.173.2.1284 – volume: 277 start-page: 1398 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0635 article-title: Leukotriene A4 hydrolase/aminopeptidase: glutamate 271 is a catalytic residue with specific roles in two distinct enzyme mechanisms publication-title: J. Biol. Chem. doi: 10.1074/jbc.M106577200 – volume: 420 start-page: 860 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0080 article-title: Inflammation and cancer publication-title: Nature doi: 10.1038/nature01322 – volume: 174 start-page: 4345 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0215 article-title: Molecular circuits of resolution: formation and actions of resolvins and protectins publication-title: J. Immunol. doi: 10.4049/jimmunol.174.7.4345 – volume: 13 start-page: 632 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0390 article-title: Resolution phase lipid mediators of inflammation: agonists of resolution publication-title: Curr. Opin. Pharmacol. doi: 10.1016/j.coph.2013.05.012 – volume: 74 start-page: 490 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0740 article-title: Neuroprotectin/protectin D1 protects against neuropathic pain in mice after nerve trauma publication-title: Ann. Neurol. doi: 10.1002/ana.23928 – volume: 287 start-page: 10070 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0615 article-title: Role of basic science in the development of new medicines: examples from the eicosanoid field publication-title: J. Biol. Chem. doi: 10.1074/jbc.X112.351437 – volume: 484 start-page: 524 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0630 article-title: Infection regulates pro-resolving mediators that lower antibiotic requirements publication-title: Nature doi: 10.1038/nature11042 – volume: 206 start-page: 15 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0275 article-title: Maresins: novel macrophage mediators with potent anti-inflammatory and pro-resolving actions publication-title: J. Exp. Med. doi: 10.1084/jem.20081880 – volume: 257 start-page: 7056 year: 1982 ident: 10.1016/j.bbalip.2014.08.006_bb0325 article-title: Formation of a novel dihydroxy acid from arachidonic acid by lipoxygenase-catalyzed double oxygenation in rat mononuclear cells and human leukocytes publication-title: J. Biol. Chem. doi: 10.1016/S0021-9258(18)34537-X – volume: 26 start-page: 1755 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0270 article-title: Macrophage pro-resolving mediator maresin 1 stimulates tissue regeneration and controls pain publication-title: FASEB J. doi: 10.1096/fj.11-201442 – volume: 182 start-page: 3223 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0365 article-title: Acute changes in dietary omega-3 and omega-6 polyunsaturated fatty acids have a pronounced impact on survival following ischemic renal injury and formation of renoprotective docosahexaenoic acid-derived protectin D1 publication-title: J. Immunol. doi: 10.4049/jimmunol.0802064 – volume: 39 start-page: 885 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0785 article-title: Plasticity of leukocytic exudates in resolving acute inflammation is regulated by microRNA and proresolving mediators publication-title: Immunity doi: 10.1016/j.immuni.2013.10.011 – volume: 3 start-page: 4 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0540 article-title: New lives given by cell death: macrophage differentiation following their encounter with apoptotic leukocytes during the resolution of inflammation publication-title: Front. Immunol. doi: 10.3389/fimmu.2012.00004 – volume: 25 start-page: 3032 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0195 article-title: A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.4225-04.2005 – volume: 339 start-page: 166 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0340 article-title: Anti-inflammatory therapy in chronic disease: challenges and opportunities publication-title: Science doi: 10.1126/science.1230720 – volume: 376 start-page: 1713 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0520 article-title: Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials publication-title: Lancet doi: 10.1016/S0140-6736(10)61543-7 – volume: 229 start-page: 1 year: 1988 ident: 10.1016/j.bbalip.2014.08.006_bb0300 article-title: Lipoxins: a new series of eicosanoids (biosynthesis, stereochemistry, and biological activities) publication-title: Adv. Exp. Med. Biol. – volume: 23 start-page: 1946 year: 2009 ident: 10.1016/j.bbalip.2014.08.006_bb0735 article-title: Obesity-induced insulin resistance and hepatic steatosis are alleviated by omega-3 fatty acids: a role for resolvins and protectins publication-title: FASEB J. doi: 10.1096/fj.08-125674 – volume: 184 start-page: 6418 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0805 article-title: Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production publication-title: J. Immunol. doi: 10.4049/jimmunol.0903816 – volume: 118 start-page: e192 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0265 article-title: Transcriptomic analyses of murine resolution-phase macrophages publication-title: Blood doi: 10.1182/blood-2011-04-345330 – year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0645 – volume: 103 start-page: 11276 year: 2006 ident: 10.1016/j.bbalip.2014.08.006_bb0755 article-title: Transgenic mice rich in endogenous n−3 fatty acids are protected from colitis publication-title: Proc. Natl. Acad. Sci. U. S. A. doi: 10.1073/pnas.0601280103 – volume: 54 start-page: 4109 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0720 article-title: Neuroprotectin D1 restores corneal nerve integrity and function after damage from experimental surgery publication-title: Invest. Ophthalmol. Vis. Sci. doi: 10.1167/iovs.13-12075 – volume: 29 start-page: 263 year: 2006 ident: 10.1016/j.bbalip.2014.08.006_bb0005 article-title: Cell survival matters: docosahexaenoic acid signaling, neuroprotection and photoreceptors publication-title: Trends Neurosci. doi: 10.1016/j.tins.2006.03.005 – volume: 135 start-page: 687 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0170 article-title: Dietary olive oil supplemented with fish oil, rich in EPA and DHA (n−3) polyunsaturated fatty acids, attenuates colonic inflammation in rats with DSS-induced colitis publication-title: J. Nutr. doi: 10.1093/jn/135.4.687 – volume: 196 start-page: 1025 year: 2002 ident: 10.1016/j.bbalip.2014.08.006_bb0045 article-title: Resolvins: a family of bioactive products of omega-3 fatty acid transformation circuits initiated by aspirin treatment that counter pro-inflammation signals publication-title: J. Exp. Med. doi: 10.1084/jem.20020760 – volume: 62 start-page: 2437 year: 1994 ident: 10.1016/j.bbalip.2014.08.006_bb0210 article-title: Lipoxygenation of docosahexaenoic acid by the rat pineal body publication-title: J. Neurochem. doi: 10.1046/j.1471-4159.1994.62062437.x – volume: 171 start-page: 6856 year: 2003 ident: 10.1016/j.bbalip.2014.08.006_bb0660 article-title: Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators publication-title: J. Immunol. doi: 10.4049/jimmunol.171.12.6856 – volume: 3 start-page: 401 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0145 article-title: Inflammatory resolution: new opportunities for drug discovery publication-title: Nat. Rev. Drug Discov. doi: 10.1038/nrd1383 – volume: 187 start-page: 5408 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0595 article-title: Resolvin D1 and its precursor docosahexaenoic acid promote resolution of adipose tissue inflammation by eliciting macrophage polarization toward an M2-like phenotype publication-title: J. Immunol. doi: 10.4049/jimmunol.1100225 – volume: 2 start-page: 612 year: 2001 ident: 10.1016/j.bbalip.2014.08.006_bb0110 article-title: Lipid mediator class switching during acute inflammation: signals in resolution publication-title: Nat. Immunol. doi: 10.1038/89759 – volume: 190 start-page: 6378 year: 2013 ident: 10.1016/j.bbalip.2014.08.006_bb0670 article-title: Inhaled carbon monoxide accelerates resolution of inflammation via unique pro-resolving mediator–heme oxygenase-1 circuits publication-title: J. Immunol. doi: 10.4049/jimmunol.1202969 – year: 1988 ident: 10.1016/j.bbalip.2014.08.006_bb0395 – volume: 115 start-page: 2774 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0710 article-title: A role for docosahexaenoic acid-derived neuroprotectin D1 in neural cell survival and Alzheimer disease publication-title: J. Clin. Invest. doi: 10.1172/JCI25420 – volume: 25 start-page: 561 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0700 article-title: Eosinophils promote resolution of acute periotonitis by producing proresolving mediators in mice publication-title: FASEB J. doi: 10.1096/fj.10-170027 – volume: vol. 23 start-page: 242 year: 1982 ident: 10.1016/j.bbalip.2014.08.006_bb0030 article-title: Current topics in inflammation and infection – volume: 52 start-page: 1601 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0750 article-title: The omega-3 fatty acid-derived neuroprotectin D1 limits hippocampal hyperexcitability and seizure susceptibility in kindling epileptogenesis publication-title: Epilepsia doi: 10.1111/j.1528-1167.2011.03081.x – volume: 71 start-page: 1081 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0815 article-title: The 12/15-lipoxygenase pathway counteracts fibroblast activation and experimental fibrosis publication-title: Ann. Rheum. Dis. doi: 10.1136/annrheumdis-2011-200745 – volume: 7 start-page: 1209 year: 2006 ident: 10.1016/j.bbalip.2014.08.006_bb0345 article-title: Apoptotic neutrophils and T cells sequester chemokines during immune response resolution via modulation of CCR5 expression publication-title: Nat. Immunol. doi: 10.1038/ni1392 – ident: 10.1016/j.bbalip.2014.08.006_bb0280 – volume: 118 start-page: e192 year: 2011 ident: 10.1016/j.bbalip.2014.08.006_bb0545 article-title: Transcriptomic analyses of murine resolution-phase macrophages publication-title: Blood doi: 10.1182/blood-2011-04-345330 – start-page: 42 year: 2006 ident: 10.1016/j.bbalip.2014.08.006_bb0535 article-title: A novel approach to resolving inflammation publication-title: Sci. Am. – volume: 140 start-page: 935 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0035 article-title: Anti-inflammatory agents: present and future publication-title: Cell doi: 10.1016/j.cell.2010.02.043 – volume: 176 start-page: 74 year: 2010 ident: 10.1016/j.bbalip.2014.08.006_bb0810 article-title: Endogenous LXA4 circuits are determinants of pathological angiogenesis in response to chronic injury publication-title: Am. J. Pathol. doi: 10.2353/ajpath.2010.090678 – volume: 5 start-page: 405 year: 2005 ident: 10.1016/j.bbalip.2014.08.006_bb0425 article-title: Aspirin and steroids: new mechanistic findings and avenues for drug discovery publication-title: Curr. Op. Pharmacol. doi: 10.1016/j.coph.2005.02.006 – volume: 30 start-page: 69 year: 2004 ident: 10.1016/j.bbalip.2014.08.006_bb0105 article-title: Novel endogenous small molecules as the checkpoint controllers in inflammation and resolution: entrée for resoleomics publication-title: Rheum. Dis. Clin. N. Am. doi: 10.1016/S0889-857X(03)00117-0 – volume: 26 start-page: 1755 year: 2012 ident: 10.1016/j.bbalip.2014.08.006_bb0570 article-title: Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain publication-title: FASEB J. doi: 10.1096/fj.11-201442 |
| SSID | ssj0015335 ssj0025309 |
| Score | 2.6075423 |
| SecondaryResourceType | review_article |
| Snippet | Acute inflammatory responses are protective, yet without timely resolution can lead to chronic inflammation and organ fibrosis. A systems approach to... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 397 |
| SubjectTerms | Animals Anti-Inflammatory Agents - pharmacology aspirin Aspirin - pharmacology biosynthesis disease models Docosahexaenoic Acids - chemistry Docosahexaenoic Acids - metabolism Eicosanoid fibrosis Humans inflammation Inflammation - metabolism Inflammation - prevention & control LC–MS–MS-based targeted lipid mediator metabolomics Leukocyte leukocytes Lipid mediator Lipoxygenases - metabolism Metabolome mice Molecular Structure pain polyunsaturated fatty acids Resolvin Signal Transduction - drug effects stereochemistry Structure-Activity Relationship tissue repair |
| Title | Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome |
| URI | https://dx.doi.org/10.1016/j.bbalip.2014.08.006 https://www.ncbi.nlm.nih.gov/pubmed/25139562 https://www.proquest.com/docview/1706207066 https://www.proquest.com/docview/2000330046 |
| Volume | 1851 |
| WOSCitedRecordID | wos000350186800009&url=https%3A%2F%2Fcvtisr.summon.serialssolutions.com%2F%23%21%2Fsearch%3Fho%3Df%26include.ft.matches%3Dt%26l%3Dnull%26q%3D |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| journalDatabaseRights | – providerCode: PRVESC databaseName: Elsevier SD Freedom Collection Journals 2021 customDbUrl: eissn: 1879-2618 dateEnd: 99991231 omitProxy: false ssIdentifier: ssj0015335 issn: 1388-1981 databaseCode: AIEXJ dateStart: 19981208 isFulltext: true titleUrlDefault: https://www.sciencedirect.com providerName: Elsevier |
| link | http://cvtisr.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lb9NAEF6lKQguCFoK5VEtEuolcuV448dyS0sqiELIIYXcrPV6rbokdkjSqvBn-SvM7PoRKKXlwMVynLXjeD7PzszON0PIa7Cwlc99aTksBgel7QZW1OkIK0mUH0eOKxzNW_s08IfDYDLho0bjR8mFuZj6WRZcXvL5fxU1HANhI3X2H8RdXRQOwD4IHbYgdtjeSvAjU3kBU18wKD5DghEGlcH1x2RG0JgWHMmnOpKg4xupKTyrSSS6-U6atYTEBAK4H0CMYTeaTHRV3nwrSnOhlSV2oQYoTX-re3CY5vI0xWoELbXC0SaIIrB8hzgAZVL05TXMOgwhlgWhcmRGz9O4MvdBoZ2K9eyAegHprZgagndfLeERx9WaCrjsJoiUzwTGdOoAU_alYD_21QLJNJ_XIx9tdy1hxihrBqJvc9PypdbmbnsNt50WhnV8QCFbU9PM5AQXM37x3ZXJxMQ1zg6iCFwirG3a7uhyr_YfancPP4bHJ4NBOO5Nxvvzrxa2NcPl_6LHywbZdHyXB02y2X3fm_SrhS6wtl0dEyj-Ssnu1CmIV3_4OuvpOu9IW0njh-RB4d7QroHlI9JQ2RbZ7maAq9k3uk91wrGW8ha5e1ju3Tsq2w5uk-81fikgg5b4fUMBvfQX9NISvTRPaIVemmZUo5euo1dfq0YvrdBLa_Q-JifHvfHRO6toEGJJjzkrpK3IRMIUoqRiTEoWc-VJ6SVcgacCQnaiIGZB1PZZkghhy4DLwOGO6CQBjx3BdkgzyzP1lFBbuW7MI5vLyOtEPEGFFSuPR7Edx5EvdgkrH3woi-r52MRlGpZpkmehEVeI4gqxt6vt7RKrOmtuqsfcMN4vZRoWFrCxbEPA5A1nviohEILA8K0VmcrPlyHWx3JgYvf-Mgb5egxr78GYJwY_1f2CA8Q4eEnPbnH2c3K_flFfkOZqca5ekjvyYpUuF3tkw58Ee8UbAJ-Gow8_AWrX-z4 |
| linkProvider | Elsevier |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Protectins+and+maresins%3A+New+pro-resolving+families+of+mediators+in+acute+inflammation+and+resolution+bioactive+metabolome&rft.jtitle=Biochimica+et+biophysica+acta.+Molecular+and+cell+biology+of+lipids&rft.au=Serhan%2C+Charles+N&rft.au=Dalli%2C+Jesmond&rft.au=Colas%2C+Romain+A&rft.au=Winkler%2C+Jeremy+W&rft.date=2015-04-01&rft.issn=1388-1981&rft.volume=1851&rft.issue=4+p.397-413&rft.spage=397&rft.epage=413&rft_id=info:doi/10.1016%2Fj.bbalip.2014.08.006&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1388-1981&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1388-1981&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1388-1981&client=summon |