Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery
Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the or...
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| Vydané v: | Journal of ophthalmology Ročník 2015; číslo 2015; s. 1 - 6 |
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| Hlavní autori: | , , , , , , |
| Médium: | Journal Article |
| Jazyk: | English |
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Cairo, Egypt
Hindawi Publishing Corporation
01.01.2015
John Wiley & Sons, Inc Wiley |
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| ISSN: | 2090-004X, 2090-0058 |
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| Abstract | Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the original study 12 years ago were recruited for clinical assessment. Seven out of the 36 patients were lost. In the original study, each eye with double-head pterygium was randomized to have pterygium excision with CAU on one “head” (temporal or nasal) and MMC on the other “head.” All patients were invited for clinical assessment for conjunctival bed status and the presence of pterygium recurrence in the current study. Results. There was no significant difference between the size, morphology, and type of pterygium among the two treatment groups. The recurrence rate of CAU group and MMC group 12 years after excision was 6.3% and 28.1%, respectively (P=0.020). Among eyes without recurrence, the conjunctival bed was graded higher in the MMC group than the CAU group (P=0.024). Conclusion. The use of conjunctival autograft has a significantly lower long-term recurrence rate than mitomycin C in double-head pterygium surgery. |
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| AbstractList | Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the original study 12 years ago were recruited for clinical assessment. Seven out of the 36 patients were lost. In the original study, each eye with double-head pterygium was randomized to have pterygium excision with CAU on one "head" (temporal or nasal) and MMC on the other "head." All patients were invited for clinical assessment for conjunctival bed status and the presence of pterygium recurrence in the current study. Results. There was no significant difference between the size, morphology, and type of pterygium among the two treatment groups. The recurrence rate of CAU group and MMC group 12 years after excision was 6.3% and 28.1%, respectively (P = 0.020). Among eyes without recurrence, the conjunctival bed was graded higher in the MMC group than the CAU group (P = 0.024). Conclusion. The use of conjunctival autograft has a significantly lower long-term recurrence rate than mitomycin C in double-head pterygium surgery. Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the original study 12 years ago were recruited for clinical assessment. Seven out of the 36 patients were lost. In the original study, each eye with double-head pterygium was randomized to have pterygium excision with CAU on one "head" (temporal or nasal) and MMC on the other "head." All patients were invited for clinical assessment for conjunctival bed status and the presence of pterygium recurrence in the current study. Results. There was no significant difference between the size, morphology, and type of pterygium among the two treatment groups. The recurrence rate of CAU group and MMC group 12 years after excision was 6.3% and 28.1%, respectively (P = 0.020). Among eyes without recurrence, the conjunctival bed was graded higher in the MMC group than the CAU group (P = 0.024). Conclusion. The use of conjunctival autograft has a significantly lower long-term recurrence rate than mitomycin C in double-head pterygium surgery.Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the original study 12 years ago were recruited for clinical assessment. Seven out of the 36 patients were lost. In the original study, each eye with double-head pterygium was randomized to have pterygium excision with CAU on one "head" (temporal or nasal) and MMC on the other "head." All patients were invited for clinical assessment for conjunctival bed status and the presence of pterygium recurrence in the current study. Results. There was no significant difference between the size, morphology, and type of pterygium among the two treatment groups. The recurrence rate of CAU group and MMC group 12 years after excision was 6.3% and 28.1%, respectively (P = 0.020). Among eyes without recurrence, the conjunctival bed was graded higher in the MMC group than the CAU group (P = 0.024). Conclusion. The use of conjunctival autograft has a significantly lower long-term recurrence rate than mitomycin C in double-head pterygium surgery. Purpose . The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods . This is a follow-up study of a comparative interventional trial. Thirty-nine eyes of the 36 patients with double-head pterygium excision in the original study 12 years ago were recruited for clinical assessment. Seven out of the 36 patients were lost. In the original study, each eye with double-head pterygium was randomized to have pterygium excision with CAU on one “head” (temporal or nasal) and MMC on the other “head.” All patients were invited for clinical assessment for conjunctival bed status and the presence of pterygium recurrence in the current study. Results . There was no significant difference between the size, morphology, and type of pterygium among the two treatment groups. The recurrence rate of CAU group and MMC group 12 years after excision was 6.3% and 28.1%, respectively ( P = 0.020 ). Among eyes without recurrence, the conjunctival bed was graded higher in the MMC group than the CAU group ( P = 0.024 ). Conclusion . The use of conjunctival autograft has a significantly lower long-term recurrence rate than mitomycin C in double-head pterygium surgery. |
| Audience | Academic |
| Author | Yuen, Hunter K. L. Wong, Ian Y. H. Li, Emmy Y. M. Wong, Raymond L. M. Chan, Tommy C. Y. Jhanji, Vishal Yeung, Emily F. Y. |
| AuthorAffiliation | 3 Department of Ophthalmology, The University of Hong Kong, Hong Kong 2 Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong 1 Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong |
| AuthorAffiliation_xml | – name: 2 Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong – name: 3 Department of Ophthalmology, The University of Hong Kong, Hong Kong – name: 1 Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong |
| Author_xml | – sequence: 1 fullname: Wong, Ian Y. H. – sequence: 2 fullname: Yeung, Emily F. Y. – sequence: 3 fullname: Yuen, Hunter K. L. – sequence: 4 fullname: Li, Emmy Y. M. – sequence: 5 fullname: Wong, Raymond L. M. – sequence: 6 fullname: Chan, Tommy C. Y. – sequence: 7 fullname: Jhanji, Vishal |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/25810921$$D View this record in MEDLINE/PubMed |
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| CitedBy_id | crossref_primary_10_1155_2018_9341846 crossref_primary_10_1097_MPG_0000000000002466 crossref_primary_10_3389_fphar_2021_671405 crossref_primary_10_1097_ICO_0000000000002545 crossref_primary_10_1080_02713683_2016_1236965 crossref_primary_10_4103_ijo_IJO_1079_19 crossref_primary_10_4103_ijo_IJO_235_20 crossref_primary_10_1097_ICO_0000000000001036 crossref_primary_10_1097_IJG_0000000000001438 |
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| Copyright | Copyright © 2015 Tommy C. Y. Chan et al. COPYRIGHT 2015 John Wiley & Sons, Inc. Copyright © 2015 Tommy C. Y. Chan et al. This work is licensed under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Copyright © 2015 Tommy C. Y. Chan et al. 2015 |
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| Snippet | Purpose. The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods. This... Purpose . The study aims to compare the long-term outcome of conjunctival autograft (CAU) and mitomycin C (MMC) in double-head pterygium surgery. Methods .... |
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| SubjectTerms | Clinical Study Complications and side effects Cornea Dosage and administration Hospitals Mitomycin Morphology Patients Physiological aspects Surgeons Surgery Transplantation |
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| Title | Twelve-Year Outcomes of Pterygium Excision with Conjunctival Autograft versus Intraoperative Mitomycin C in Double-Head Pterygium Surgery |
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