Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model

Chronic stress and depressive-like behaviors in basic neuroscience research have been associated with impairments of neuroplasticity, such as neuronal atrophy and synaptic loss in the medial prefrontal cortex (mPFC) and hippocampus. The current review presents a novel integrative model of neuroplast...

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Bibliographic Details
Published in:	Molecular psychiatry Vol. 25; no. 3; pp. 530 - 543
Main Authors:	Price, Rebecca B, Duman, Ronald
Format:	Journal Article
Language:	English
Published:	England Nature Publishing Group 01.03.2020
Subjects:	Animal models Animals Anxiety Atrophy Behavior Brain - physiopathology Brain research Brain-derived neurotrophic factor Clinical psychology Cognition - physiology Cognition Disorders - physiopathology Cognitive ability Cognitive Dysfunction - physiopathology Depression - physiopathology Depressive Disorder - physiopathology Emotions Executive function Functional morphology Functional plasticity Gene expression Hippocampus - physiopathology Humans Information processing Ketamine Memory Memory - physiology Mental depression Nerve Net - physiopathology Nervous system Neural networks Neuroimaging Neuronal Plasticity - physiology Neurons Neuroplasticity Neurosciences Prefrontal cortex Prefrontal Cortex - physiopathology Psychiatry Stress Stress, Psychological - psychology Synaptic plasticity
ISSN:	1359-4184, 1476-5578, 1476-5578
Online Access:	Get full text
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