Oscillatory Regulation of Hes1: Discrete Stochastic Delay Modelling and Simulation

Discrete stochastic simulations are a powerful tool for understanding the dynamics of chemical kinetics when there are small-to-moderate numbers of certain molecular species. In this paper we introduce delays into the stochastic simulation algorithm, thus mimicking delays associated with transcripti...

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Vydáno v:	PLoS computational biology Ročník 2; číslo 9; s. e117
Hlavní autoři:	Barrio, Manuel, Burrage, Kevin, Leier, André, Tian, Tianhai
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	United States Public Library of Science 01.09.2006 Public Library of Science (PLoS)
Témata:	Algorithms Bioinformatics - Computational Biology Chemical kinetics Colleges & universities Computational Biology Computer Simulation Experiments Gene Expression Regulation Genetic algorithms Genetic regulation Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Introduced species Mathematical models Messenger RNA Models, Biological Molecular Sequence Data Mus (Mouse) Noise Ordinary differential equations Proteins RNA, Messenger - genetics Sensitivity analysis Sensitivity and Specificity Simulation Stochastic analysis Stochastic Processes Systems Biology Stochastic Processes Homeodomain Proteins Models, Biological Sensitivity & Specificity Computer Simulation Computational Biology Gene Expression Regulation Molecular Sequence Data RNA, Messenger
ISSN:	1553-7358, 1553-734X, 1553-7358
On-line přístup:	Získat plný text
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