Serum biomarkers of treatment response within a randomized clinical trial for pulmonary tuberculosis

Biomarkers for monitoring response to anti-tuberculosis treatment are needed. We explored immune markers previously published as having predictive capability for 8 week culture status in 39 adults enrolled in a clinical trial in Kampala, Uganda. We consecutively selected 20 HIV-negative pulmonary TB...

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Bibliographic Details
Published in:	Tuberculosis (Edinburgh, Scotland) Vol. 95; no. 4; pp. 415 - 420
Main Authors:	Jayakumar, A., Vittinghoff, E., Segal, M.R., MacKenzie, W.R., Johnson, J.L., Gitta, P., Saukkonen, J., Anderson, J., Weiner, M., Engle, M., Yoon, C., Kato-Maeda, M., Nahid, P.
Format:	Journal Article
Language:	English
Published:	Scotland Elsevier Ltd 01.07.2015
Subjects:	Adult Age Factors Antitubercular Agents - therapeutic use Biomarkers Biomarkers - blood C-Reactive Protein - metabolism Cytokines - blood Enzyme-Linked Immunosorbent Assay Female Host-Pathogen Interactions Humans Infectious Disease Logistic Models Male Multivariate Analysis Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - immunology Mycobacterium tuberculosis - pathogenicity Predictive Value of Tests Pulmonary Pulmonary/Respiratory Receptors, Cytokine - blood Receptors, Tumor Necrosis Factor, Type I - blood Time Factors Treatment Outcome Treatment response Tuberculosis Tuberculosis, Pulmonary - blood Tuberculosis, Pulmonary - diagnosis Tuberculosis, Pulmonary - drug therapy Tuberculosis, Pulmonary - immunology Tuberculosis, Pulmonary - microbiology Uganda Young Adult Uganda Biomarkers Treatment response Tuberculosis Pulmonary
ISSN:	1472-9792, 1873-281X, 1873-281X
Online Access:	Get full text
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