BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation

BRCA1-associated protein 1 (BAP1) regulates calcium flux in the endoplasmic reticulum to facilitate the execution of apoptosis, unveiling a new facet of the role of BAP1 as an environmental tumour suppressor. A new role for BAP1 in tumour suppression BAP1 is a tumour suppressor associated with germl...

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Bibliographic Details
Published in:	Nature (London) Vol. 546; no. 7659; pp. 549 - 553
Main Authors:	Bononi, Angela, Giorgi, Carlotta, Patergnani, Simone, Larson, David, Verbruggen, Kaitlyn, Tanji, Mika, Pellegrini, Laura, Signorato, Valentina, Olivetto, Federica, Pastorino, Sandra, Nasu, Masaki, Napolitano, Andrea, Gaudino, Giovanni, Morris, Paul, Sakamoto, Greg, Ferris, Laura K., Danese, Alberto, Raimondi, Andrea, Tacchetti, Carlo, Kuchay, Shafi, Pass, Harvey I., Affar, El Bachir, Yang, Haining, Pinton, Paolo, Carbone, Michele
Format:	Journal Article
Language:	English
Published:	London Nature Publishing Group UK 22.06.2017 Nature Publishing Group
Subjects:	13/1 13/106 13/109 13/89 13/95 14/1 14/19 14/28 14/33 14/35 14/63 38/109 38/88 38/89 631/67/1641 631/67/68 631/80/86/1999 82 82/29 82/83 96/2 96/31 Cell interactions Humanities and Social Sciences letter multidisciplinary Observations Physiological aspects Science Tumor suppressor genes
ISSN:	0028-0836, 1476-4687, 1476-4687
Online Access:	Get full text
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