Multidrug-Resistant Tuberculosis 
Outbreak among US-bound Hmong 
Refugees, Thailand, 2005

In January 2005, tuberculosis (TB), including multidrug-resistant TB (MDR TB), was reported among Hmong refugees who were living in or had recently immigrated to the United States from a camp in Thailand. We investigated TB and drug resistance, enhanced TB screenings, and expanded treatment capacity...

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Bibliographic Details
Published in:Emerging infectious diseases Vol. 14; no. 11; pp. 1715 - 1721
Main Authors: Oeltmann, John E., Varma, Jay K., Ortega, Luis, Liu, Yecai, O’Rourke, Thomas, Cano, Maria, Harrington, Theresa, Toney, Sean, Jones, Warren, Karuchit, Samart, Diem, Lois, Rienthong, Dhanida, Tappero, Jordan W., Ijaz, Kashef, Maloney, Susan A.
Format: Journal Article
Language:English
Published: United States U.S. National Center for Infectious Diseases 01.11.2008
Centers for Disease Control and Prevention
Subjects:
Antitubercular Agents - pharmacology
Antitubercular Agents - therapeutic use
Bacterial Typing Techniques
Care and treatment
Disease Outbreaks
DNA, Bacterial - analysis
Drug resistance in microorganisms
Drug Resistance, Multiple, Bacterial
Humans
Mass Screening
multidrug-resistant tuberculosis
Mycobacterium tuberculosis - classification
Mycobacterium tuberculosis - drug effects
Mycobacterium tuberculosis - isolation & purification
outbreak
Refugees
Sputum - microbiology
Thailand
Thailand - ethnology
Tuberculosis
tuberculosis screening
Tuberculosis, Multidrug-Resistant - drug therapy
Tuberculosis, Multidrug-Resistant - epidemiology
Tuberculosis, Multidrug-Resistant - microbiology
United States - epidemiology
Thailand
United States
ISSN:1080-6040, 1080-6059, 1080-6059
Online Access:Get full text
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Summary:In January 2005, tuberculosis (TB), including multidrug-resistant TB (MDR TB), was reported among Hmong refugees who were living in or had recently immigrated to the United States from a camp in Thailand. We investigated TB and drug resistance, enhanced TB screenings, and expanded treatment capacity in the camp. In February 2005, 272 patients with TB (24 MDR TB) remained in the camp. Among 17 MDR TB patients interviewed, 13 were found to be linked socially. Of 23 MDR TB isolates genotyped, 20 were similar according to 3 molecular typing methods. Before enhanced screening was implemented, 46 TB cases (6 MDR TB) were diagnosed in the United States among 9,455 resettled refugees. After enhanced screening had begun, only 4 TB cases (1 MDR TB), were found among 5,705 resettled refugees. An MDR TB outbreak among US-bound refugees led to importation of disease; enhanced pre-immigration TB screening and treatment decreased subsequent importation.
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ISSN:1080-6040
1080-6059
1080-6059
DOI:10.3201/eid1411.071629