Zinc, magnesium and NMDA receptor alterations in the hippocampus of suicide victims

There is evidence for an association between suicidal behavior and depression. Accumulating data suggests that depression is related to a dysfunction of the brain's glutamatergic system, and that the N-methyl-d-aspartate (NMDA) receptor plays an important role in antidepressant activity. Zinc a...

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Bibliographic Details
Published in:	Journal of affective disorders Vol. 151; no. 3; pp. 924 - 931
Main Authors:	Sowa-Kućma, Magdalena, Szewczyk, Bernadeta, Sadlik, Krystyna, Piekoszewski, Wojciech, Trela, Franciszek, Opoka, Włodzimierz, Poleszak, Ewa, Pilc, Andrzej, Nowak, Gabriel
Format:	Journal Article
Language:	English
Published:	Oxford Elsevier B.V 01.12.2013 Elsevier
Subjects:	Adolescent Adult Adult and adolescent clinical studies Aged Antidepressant drugs Antidepressive Agents - metabolism Biological and medical sciences Depression Dizocilpine Maleate - antagonists & inhibitors Dizocilpine Maleate - metabolism Female Hippocampus Hippocampus - metabolism Humans Magnesium Magnesium - metabolism Male Medical sciences Middle Aged Miscellaneous Mood disorders N-Methylaspartate - metabolism NMDA receptor Pathophysiological aspects Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Radioligand Assay Receptors, N-Methyl-D-Aspartate - metabolism Suicide Young Adult Zinc Zinc - metabolism Depression Magnesium NMDA receptor Suicide Zinc Hippocampus Mood disorder Central nervous system Glutamate receptor Inorganic element Encephalon Victim
ISSN:	0165-0327, 1573-2517, 1573-2517
Online Access:	Get full text
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