Genetic variability in the regulation of gene expression in ten regions of the human brain

Expression quantitative trait loci (eQTLs) are genomic regions that regulate gene expression. Here the authors provide a publicly available data set of exon-level eQTLs across the human brain. This includes many genome-wide association study (GWAS) hits for neurological and psychiatric disorders. Ge...

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Veröffentlicht in:	Nature neuroscience Jg. 17; H. 10; S. 1418 - 1428
Hauptverfasser:	Ramasamy, Adaikalavan, Trabzuni, Daniah, Guelfi, Sebastian, Varghese, Vibin, Smith, Colin, Walker, Robert, De, Tisham, Coin, Lachlan, de Silva, Rohan, Cookson, Mark R, Singleton, Andrew B, Hardy, John, Ryten, Mina, Weale, Michael E
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	New York Nature Publishing Group US 01.10.2014 Nature Publishing Group
Schlagworte:	38/61 631/1647/2217/2218 631/208/205/2138 631/208/212/2019 631/378/2583 Adolescent Adult Aged Aged, 80 and over Animal Genetics and Genomics Behavioral Sciences Biological Techniques Biomedicine Brain - anatomy & histology Brain - metabolism Brain mapping Brain research Datasets Female Gene expression Gene Expression Profiling Gene Expression Regulation Genetic aspects Genetic Association Studies Genetic Predisposition to Disease Genetic research Genomes Health risk assessment Humans Identification and classification Male Middle Aged Nervous System Diseases - genetics Nervous System Diseases - pathology Neurobiology Neurological disorders Neurosciences Oligonucleotide Array Sequence Analysis Polymorphism, Single Nucleotide Quality control Quantitative Trait Loci resource Young Adult United Kingdom > UK
ISSN:	1097-6256, 1546-1726, 1546-1726
Online-Zugang:	Volltext
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