Biological in-vivo measurement of dose distribution in patients' lymphocytes by gamma-H2AX immunofluorescence staining: 3D conformal- vs. step-and-shoot IMRT of the prostate gland

Background Different radiation-techniques in treating local staged prostate cancer differ in their dose- distribution. Physical phantom measurements indicate that for 3D, less healthy tissue is exposed to a relatively higher dose compared to SSIMRT. The purpose is to substantiate a dose distribution...

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Veröffentlicht in:	Radiation oncology (London, England) Jg. 6; H. 1; S. 62
Hauptverfasser:	Zwicker, Felix, Swartman, Benedict, Sterzing, Florian, Major, Gerald, Weber, Klaus-Josef, Huber, Peter E, Thieke, Christian, Debus, Jürgen, Herfarth, Klaus
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London BioMed Central 07.06.2011 BioMed Central Ltd BMC
Schlagworte:	Aged Aged, 80 and over Biomedical and Life Sciences Biomedicine Cancer Research Cell Nucleus - radiation effects Dose-Response Relationship, Radiation Equipment and supplies Fluorescent antibody technique Histones - metabolism Humans Imaging Imaging, Three-Dimensional - methods Immunofluorescence Leukocytes - radiation effects Lymphocytes Lymphocytes - radiation effects Male Medical examination Methods Microscopy, Fluorescence - methods Middle Aged Oncology Physiological aspects Prostate Prostatic Neoplasms - radiotherapy Radiology Radiotherapy Radiotherapy, Conformal - methods Regression Analysis Stains and staining (Microscopy) Germany Linear Regression Curve Prostate Cancer Treatment Applied Dose Dose Distribution Total Body Volume
ISSN:	1748-717X, 1748-717X
Online-Zugang:	Volltext
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