Jane: a new tool for the cophylogeny reconstruction problem
Background This paper describes the theory and implementation of a new software tool, called Jane , for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (asso...
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| Veröffentlicht in: | Algorithms for molecular biology Jg. 5; H. 1; S. 16 |
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| Hauptverfasser: | , , , |
| Format: | Journal Article |
| Sprache: | Englisch |
| Veröffentlicht: |
London
BioMed Central
03.02.2010
BioMed Central Ltd BMC |
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| ISSN: | 1748-7188, 1748-7188 |
| Online-Zugang: | Volltext |
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| Abstract | Background
This paper describes the theory and implementation of a new software tool, called
Jane
, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new
Jane
tool described here provides functionality that complements existing tools.
Results
The
Jane
software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions.
Jane
also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program.
Conclusions
Jane
is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography. |
|---|---|
| AbstractList | This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools.
The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program.
Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography. This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools.BACKGROUNDThis paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools.The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program.RESULTSThe Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program.Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography.CONCLUSIONSJane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography. This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools. The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program. Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography. Abstract Background This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools. Results The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program. Conclusions Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography. Background This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools. Results The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program. Conclusions Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography. Background This paper describes the theory and implementation of a new software tool, called Jane , for the study of historical associations. This problem arises in parasitology (associations of hosts and parasites), molecular systematics (associations of orderings and genes), and biogeography (associations of regions and orderings). The underlying problem is that of reconciling pairs of trees subject to biologically plausible events and costs associated with these events. Existing software tools for this problem have strengths and limitations, and the new Jane tool described here provides functionality that complements existing tools. Results The Jane software tool uses a polynomial time dynamic programming algorithm in conjunction with a genetic algorithm to find very good, and often optimal, solutions even for relatively large pairs of trees. The tool allows the user to provide rich timing information on both the host and parasite trees. In addition the user can limit host switch distance and specify multiple host switch costs by specifying regions in the host tree and costs for host switches between pairs of regions. Jane also provides a graphical user interface that allows the user to interactively experiment with modifications to the solutions found by the program. Conclusions Jane is shown to be a useful tool for cophylogenetic reconstruction. Its functionality complements existing tools and it is therefore likely to be of use to researchers in the areas of parasitology, molecular systematics, and biogeography. |
| ArticleNumber | 16 |
| Audience | Academic |
| Author | Ovadia, Yaniv Libeskind-Hadas, Ran Fielder, Daniel Conow, Chris |
| AuthorAffiliation | 2 Department of Computer Science, California State Polytechnic University, Pomona, CA, USA 1 Department of Computer Science, Harvey Mudd College, Claremont CA, USA |
| AuthorAffiliation_xml | – name: 1 Department of Computer Science, Harvey Mudd College, Claremont CA, USA – name: 2 Department of Computer Science, California State Polytechnic University, Pomona, CA, USA |
| Author_xml | – sequence: 1 givenname: Chris surname: Conow fullname: Conow, Chris organization: Department of Computer Science, California State Polytechnic University – sequence: 2 givenname: Daniel surname: Fielder fullname: Fielder, Daniel organization: Department of Computer Science, Harvey Mudd College – sequence: 3 givenname: Yaniv surname: Ovadia fullname: Ovadia, Yaniv organization: Department of Computer Science, Harvey Mudd College – sequence: 4 givenname: Ran surname: Libeskind-Hadas fullname: Libeskind-Hadas, Ran email: hadas@cs.hmc.edu organization: Department of Computer Science, Harvey Mudd College |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/20181081$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/S0025-5564(97)10012-8 10.1080/10635150701311370 10.1111/j.0014-3820.2004.tb00479.x 10.1080/10635150490264996 10.1017/S0031182003002993 10.1017/S1464793104006463 10.1089/cmb.2008.0084 10.1038/332258a0 10.1080/10635159950127303 10.1016/S1055-7903(03)00227-6 10.1016/j.thbio.2005.01.003 10.1111/j.1420-9101.2007.01340.x 10.1080/10635150490265021 10.1046/j.1365-294X.2002.01529.x |
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| References | D Merkle (89_CR7) 2005; 123 M Charleston (89_CR5) 1998; 149 AM Paterson (89_CR15) 2000; 49 DM Percy (89_CR20) 2004; 53 MS Hafner (89_CR14) 1988; 332 AP Jackson (89_CR16) 2004; 79 J Hughes (89_CR21) 2007; 56 AP Jackson (89_CR11) 2004; 55 G Refrégier (89_CR18) 2008 GD Weiblen (89_CR17) 2002; 11 RD Page (89_CR22) 2004; 30 89_CR9 89_CR13 R Libeskind-Hadas (89_CR1) 2009; 16 89_CR8 89_CR6 MD Sorenson (89_CR19) 2004; 53 89_CR3 89_CR4 R Poulin (89_CR12) 2003; 126 89_CR2 DM De Vienne (89_CR10) 2007; 20 15012944 - Mol Phylogenet Evol. 2004 Mar;30(3):633-52 12116418 - Syst Biol. 2000 Sep;49(3):383-99 9621683 - Math Biosci. 1998 May;149(2):191-223 17584237 - J Evol Biol. 2007 Jul;20(4):1428-38 15521451 - Evolution. 2004 Sep;58(9):1909-23 15682869 - Biol Rev Camb Philos Soc. 2004 Nov;79(4):751-68 12144676 - Mol Ecol. 2002 Aug;11(8):1573-8 17464880 - Syst Biol. 2007 Apr;56(2):232-51 12793652 - Parasitology. 2003 May;126(Pt 5):473-80 14965909 - Syst Biol. 2004 Feb;53(1):140-53 18202869 - Theory Biosci. 2005 Apr;123(4):277-99 3347269 - Nature. 1988 Mar 17;332(6161):258-9 18371215 - BMC Evol Biol. 2008 Mar 27;8:100 14965907 - Syst Biol. 2004 Feb;53(1):120-7 19119995 - J Comput Biol. 2009 Jan;16(1):105-17 |
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This paper describes the theory and implementation of a new software tool, called
Jane
, for the study of historical associations. This problem... This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem arises in... Background This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This problem... Abstract Background This paper describes the theory and implementation of a new software tool, called Jane, for the study of historical associations. This... |
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| SubjectTerms | Algorithms Bioinformatics Biomedical and Life Sciences Cellular and Medical Topics Computational Biology/Bioinformatics Genetic algorithms Genetic aspects Life Sciences Methods Natural history Parasites Phylogenetic trees Physiological Software Article |
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| Title | Jane: a new tool for the cophylogeny reconstruction problem |
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