Long-term cardiovascular disorders in the STOX1 mouse model of preeclampsia

Adverse long-term cardiovascular (CV) consequences of PE are well established in women. However, the mechanism responsible for that risk remains unknown. Here, we mated wild-type female mice of the FVB/N strain to STOX1A-overexpressing mice to mimic severe PE and investigated the long-term consequen...

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Veröffentlicht in:	Scientific reports Jg. 9; H. 1; S. 11918 - 13
Hauptverfasser:	Miralles, Francisco, Collinot, Hélène, Boumerdassi, Yasmine, Ducat, Aurélien, Duché, Angéline, Renault, Gilles, Marchiol, Carmen, Lagoutte, Isabelle, Bertholle, Céline, Andrieu, Muriel, Jacques, Sébastien, Méhats, Céline, Vaiman, Daniel
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	London Nature Publishing Group UK 15.08.2019 Nature Publishing Group
Schlagworte:	45/61 59 631/443/592/1540 631/443/592/75/243/793 64/60 Animals Body Weight Cardiovascular Diseases - blood Cardiovascular Diseases - diagnostic imaging Cardiovascular Diseases - etiology Cardiovascular Diseases - genetics Cardiovascular system Carrier Proteins - metabolism Cellular stress response Chemokines CXCL11 protein CXCL13 protein CXCL16 protein Cytokines - metabolism Deregulation Disease Models, Animal Doppler effect Endothelial cells Endothelial Cells - metabolism Female Females Fibrosis Gene Expression Regulation Heart Histology Humanities and Social Sciences Hypertrophy Interleukin 10 Interleukin 16 Interleukin 2 Interleukin 4 Interleukin 6 Life Sciences multidisciplinary Myocardium - pathology Organ Size Pre-eclampsia Pre-Eclampsia - blood Pre-Eclampsia - pathology Preeclampsia Pregnancy Reproductive Biology Rodents Science Science (multidisciplinary) Transcription, Genetic Ultrasonic imaging Ultrasound Ventricle
ISSN:	2045-2322, 2045-2322
Online-Zugang:	Volltext
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