Presurgical diffusion metrics of the thalamus and thalamic nuclei in postoperative delirium: A prospective two-centre cohort study in older patients

•The neuronal basis of postoperative delirium is a subject of ongoing research.•This study used diffusion kurtosis imaging to elucidate the role of the structural integrity of the thalamus prior to surgery.•Thalamic mean diffusivity was found to be associated with postoperative delirium.•Thalamic nu...

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Bibliographic Details
Published in:	NeuroImage clinical Vol. 36; p. 103208
Main Authors:	Fislage, Marinus, Winzeck, Stefan, Stamatakis, Emmanuel, Correia, Marta M., Preller, Jacobus, Feinkohl, Insa, Spies, Claudia D., Hendrikse, Jeroen, J.C Slooter, Arjen, Winterer, Georg, Pischon, Tobias, Menon, David K., Zacharias, Norman
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Inc 01.01.2022 Elsevier
Subjects:	Aged Cohort Studies Diffusion kurtosis imaging Diffusion magnetic resonance imaging Diffusion Tensor Imaging - methods Emergence Delirium Humans Neuroscience and Neuroanaesthesia Postoperative delirium Prospective Studies Radiology Regular Thalamic function Thalamic Nuclei Thalamus - diagnostic imaging 3T Diffusion magnetic resonance imaging MRI Diffusion kurtosis imaging STROBE Nu-DESC FW QC MMSE SNR MD IDPs Neuroscience and Neuroanaesthesia Thalamic function MK CAM-ICU DKI POD RASS BioCog ROI CAM AP TE Postoperative delirium FA T1w TR ZNCC 3 Tesla Fractional Anisotropy Echo Time Richmond Agitation Sedation Scale Repitition Time Mini–Mental State Examination image derived phenotypes zero-normalised cross-correlation quality control Mean Kurtosis T1-weighted Free Water Magnetic Resonance Imaging signal to noise ratio Mean Diffusivity Confusion Assessment Method Confusion Assessment Method for the Intensive Care Unit anisotropic power STrengthening the Reporting of OBservational studies in Epidemiology Biomarker Development for Postoperative Cognitive Impairment in the Elderly region of interest Nursing Delirium Screening
ISSN:	2213-1582, 2213-1582
Online Access:	Get full text
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