Premature deaths attributable to blood pressure in China: a prospective cohort study

Hypertension is a major global-health challenge because of its high prevalence and concomitant risks of cardiovascular disease. We estimated premature deaths attributable to increased blood pressure in China. We did a prospective cohort study in a nationally representative sample of 169 871 Chinese...

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Vydáno v:	The Lancet (British edition) Ročník 374; číslo 9703; s. 1765 - 1772
Hlavní autoři:	He, Jiang, Gu, Dongfeng, Chen, Jing, Wu, Xigui, Kelly, Tanika N, Huang, Jian-feng, Chen, Ji-chun, Chen, Chung-Shiuan, Bazzano, Lydia A, Reynolds, Kristi, Whelton, Paul K, Klag, Michael J
Médium:	Journal Article
Jazyk:	angličtina
Vydáno:	Kidlington Elsevier Ltd 21.11.2009 Elsevier Elsevier Limited
Témata:	Adult Adults Aged Biological and medical sciences Blood pressure Cardiovascular disease Cardiovascular diseases Cause of Death China - epidemiology Cohort Studies Deaths Developing countries Disease prevention Estimates Female General aspects Health risks Health services Hospitals Humans Hypertension Hypertension - complications Hypertension - mortality Internal Medicine LDCs Life Expectancy Male Medical records Medical sciences Middle Aged Miscellaneous Mortality Physical examinations Population number Pressure measurement Prevalence Provinces Public health Public health. Hygiene Public health. Hygiene-occupational medicine Risk Factors Sex Factors Smoking Womens health Asia China USA China, People's Rep Medicine Prospective Premature Cohort study Mortality Death Arterial pressure Blood pressure Hemodynamics Public health
ISSN:	0140-6736, 1474-547X, 1474-547X
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Shrnutí:	Hypertension is a major global-health challenge because of its high prevalence and concomitant risks of cardiovascular disease. We estimated premature deaths attributable to increased blood pressure in China. We did a prospective cohort study in a nationally representative sample of 169 871 Chinese adults aged 40 years and older. Blood pressure and other risk factors were measured at a baseline examination in 1991 and follow-up assessment was done in 1999–2000. Premature death was defined as mortality before age 72 years in men and 75 years in women, which were the average life expectancies in China in 2005. We calculated the numbers of total and premature deaths attributable to blood pressure using population-attributable risk, mortality, and the population size of China in 2005. Hypertension and prehypertension were significantly associated with increased all-cause and cardiovascular mortality (p<0·0001). We estimated that in 2005, 2·33 million (95% CI 2·21–2·45) cardiovascular deaths were attributable to increased blood pressure in China: 2·11 million (2·03–2·20) in adults with hypertension and 0·22 million (0·19–0·25) in adults with prehypertension. Additionally, 1·27 million (1·18–1·36) premature cardiovascular deaths were attributable to raised blood pressure in China: 1·15 million (1·08–1·22) in adults with hypertension and 0·12 million (0·10–0·14) in adults with prehypertension. Most blood pressure-related deaths were caused by cerebrovascular diseases: 1·86 million (1·76–1·96) total deaths and 1·08 million (1·00–1·15) premature deaths. Increased blood pressure is the leading preventable risk factor for premature mortality in the Chinese general population. Prevention and control of this condition should receive top public-health priority in China. American Heart Association (USA); National Heart, Lung, and Blood Institute, National Institutes of Health (USA); Ministry of Health (China); and Ministry of Science and Technology (China).
Bibliografie:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23
ISSN:	0140-6736 1474-547X 1474-547X
DOI:	10.1016/S0140-6736(09)61199-5