ADAM33 gene silencing by promoter hypermethylation as a molecular marker in breast invasive lobular carcinoma

Background ADAM33 protein is a member of the family of transmembrane glycoproteins composed of multidomains. ADAM family members have different activities, such as proteolysis and adhesion, making them good candidates to mediate the extracellular matrix remodelling and changes in cellular adhesion t...

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Bibliographic Details
Published in:	BMC cancer Vol. 9; no. 1; p. 80
Main Authors:	Seniski, Gerusa G, Camargo, Anamaria A, Ierardi, Daniela F, Ramos, Edneia AS, Grochoski, Mariana, Ribeiro, Enilze SF, Cavalli, Iglenir J, Pedrosa, Fabio O, de Souza, Emanuel M, Zanata, Silvio M, Costa, Fabrício F, Klassen, Giseli
Format:	Journal Article
Language:	English
Published:	London BioMed Central 06.03.2009 BioMed Central Ltd BMC
Subjects:	ADAM Proteins - genetics Adult Aged Aged, 80 and over Biomarkers, Tumor - genetics Biomedical and Life Sciences Biomedicine Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Research Carcinoma, Ductal, Breast - genetics Carcinoma, Lobular - genetics Carcinoma, Lobular - pathology Cell Line, Tumor Control Development and progression DNA Methylation Female Gene Expression - genetics Gene Silencing Genetic aspects Glycoproteins Health aspects Health Promotion and Disease Prevention Humans Medicine/Public Health Methods Middle Aged Oncology Promoter Regions, Genetic - genetics Research Article Surgical Oncology Tumor markers Brazil Invasive Lobular Carcinoma Invasive Ductal Carcinoma Breast Tumour Cell Line Methylation Frequency ADAM33 Expression
ISSN:	1471-2407, 1471-2407
Online Access:	Get full text
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