Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis

Melioidosis, caused by bioterror treat agent Burkholderia pseudomallei, is an important cause of community-acquired Gram-negative sepsis in Southeast Asia and Northern Australia. New insights into the pathogenesis of melioidosis may help improve treatment and decrease mortality rates from this dread...

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Bibliographic Details
Published in:	PLoS neglected tropical diseases Vol. 11; no. 3; p. e0005468
Main Authors:	Birnie, Emma, Koh, Gavin C. K. W., Löwenberg, Ester C., Meijers, Joost C. M., Maude, Rapeephan R., Day, Nicholas P. J., Peacock, Sharon J., Poll, Tom van der, Wiersinga, W. Joost
Format:	Journal Article
Language:	English
Published:	United States Public Library of Science 15.03.2017 Public Library of Science (PLoS)
Subjects:	ADAMTS13 Protein - analysis Adolescent Adult Aged Antibiotics Antigens Biology and Life Sciences Blood platelets Burkholderia pseudomallei Burkholderia pseudomallei - isolation & purification Correlation Cytokines Diagnosis Endotoxins Female Health aspects Hospitals Humans Immunology Infections Infectious diseases Inflammation Intensive care Male Measurement Medicine Medicine and Health Sciences Melioidosis - mortality Melioidosis - pathology Middle Aged Mortality Pathogenesis People and Places Pseudomonas infections Public health Sepsis Stimulation Survival Analysis Thailand Thrombin Thrombocytopenia Thrombocytopenia - pathology Thrombosis Tropical diseases Vaccines Von Willebrand factor von Willebrand Factor - analysis Young Adult Southeast Asia Netherlands Thailand Australia Bangkok Thailand
ISSN:	1935-2735, 1935-2727, 1935-2735
Online Access:	Get full text
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