The effect of stromal components on the modulation of the phenotype of human bronchial epithelial cells in 3D culture

The stroma plays an important role in the development and progression of human diseases. Pulmonary diseases such as asthma, fibrosis and cancer are thought to be the result of altered communications between the epithelial and stromal tissue compartments. In order to study these epithelial–mesenchyma...

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Bibliographic Details
Published in:	Biomaterials Vol. 32; no. 29; pp. 7169 - 7180
Main Authors:	Pageau, Steven C., Sazonova, Olga V., Wong, Joyce Y., Soto, Ana M., Sonnenschein, Carlos
Format:	Journal Article
Language:	English
Published:	Netherlands Elsevier Ltd 01.10.2011
Subjects:	adults Advanced Basic Science Animals apoptosis asthma biomechanics Bronchi - cytology Bronchi - pathology Bronchi - physiology Cell Culture Techniques cell viability Cells, Cultured Co-culture Coculture Techniques Collagen Collagen - metabolism Connective Tissue - anatomy & histology Connective Tissue - metabolism Dentistry ECM (extracellular matrix) epithelial cells Epithelial Cells - cytology Epithelial Cells - physiology epithelium extracellular matrix Extracellular Matrix - chemistry Extracellular Matrix - metabolism Fibroblast fibroblasts Fibroblasts - cytology Fibroblasts - physiology fibrosis gels Gene Expression genes human diseases Humans immune response Lung Lung Neoplasms - pathology mitosis Phenotype Stromal Cells - cytology Stromal Cells - physiology ECM (extracellular matrix) Co-culture Fibroblast Collagen Lung
ISSN:	0142-9612, 1878-5905, 1878-5905
Online Access:	Get full text
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