Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

Heart failure (HF) is a morbid and heritable disorder for which the biological mechanisms are incompletely understood. We therefore examined genetic associations with HF in a large national biobank, and assessed whether refined phenotypic classification would facilitate genetic discovery. We defined...

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Bibliographic Details

Published in:	Circulation (New York, N.Y.) Vol. 139; no. 4; p. 489
Main Authors:	Aragam, Krishna G, Chaffin, Mark, Levinson, Rebecca T, McDermott, Gregory, Choi, Seung Hoan, Shoemaker, M Benjamin, Haas, Mary E, Weng, Lu-Chen, Lindsay, Mark E, Smith, J Gustav, Newton-Cheh, Christopher, Roden, Dan M, London, Barry, Wells, Quinn S, Ellinor, Patrick T, Kathiresan, Sekar, Lubitz, Steven A
Format:	Journal Article
Language:	English
Published:	United States 22.01.2019
Subjects:	heart failure cardiomyopathy, dilated cardiomyopathies genome-wide association study
ISSN:	1524-4539, 1524-4539
Online Access:	Get more information
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