Phenotypic Refinement of Heart Failure in a National Biobank Facilitates Genetic Discovery

Heart failure (HF) is a morbid and heritable disorder for which the biological mechanisms are incompletely understood. We therefore examined genetic associations with HF in a large national biobank, and assessed whether refined phenotypic classification would facilitate genetic discovery. We defined...

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Veröffentlicht in:	Circulation (New York, N.Y.) Jg. 139; H. 4; S. 489
Hauptverfasser:	Aragam, Krishna G, Chaffin, Mark, Levinson, Rebecca T, McDermott, Gregory, Choi, Seung Hoan, Shoemaker, M Benjamin, Haas, Mary E, Weng, Lu-Chen, Lindsay, Mark E, Smith, J Gustav, Newton-Cheh, Christopher, Roden, Dan M, London, Barry, Wells, Quinn S, Ellinor, Patrick T, Kathiresan, Sekar, Lubitz, Steven A
Format:	Journal Article
Sprache:	Englisch
Veröffentlicht:	United States 22.01.2019
Schlagworte:	heart failure cardiomyopathy, dilated cardiomyopathies genome-wide association study
ISSN:	1524-4539, 1524-4539
Online-Zugang:	Weitere Angaben
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