Quantitative theory of entropic forces acting on constrained nucleotide sequences applied to viruses

We outline a theory to quantify the interplay of entropic and selective forces on nucleotide organization and apply it to the genomes of single-stranded RNA viruses. We quantify these forces as intensive variables that can easily be compared between sequences, outline a computationally efficient tra...

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Bibliographic Details

Published in:	Proceedings of the National Academy of Sciences - PNAS Vol. 111; no. 13; p. 5054
Main Authors:	Greenbaum, Benjamin D, Cocco, Simona, Levine, Arnold J, Monasson, Rémi
Format:	Journal Article
Language:	English
Published:	United States 01.04.2014
Subjects:	Base Sequence Codon - genetics Computer Simulation Dinucleoside Phosphates - genetics Entropy Humans Influenza A Virus, H1N1 Subtype - genetics Models, Biological Molecular Mimicry Nucleotide Motifs Viruses - genetics
ISSN:	1091-6490, 1091-6490
Online Access:	Get more information
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